(61 nodes) Glycerolipid metabolism network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103462875	acidPPc domain-containing protein. (328 aa)
	LOC103464949	Zgc:123305. (969 aa)
	LOC103470380	Aldo-keto reductase family 1, member A1a (aldehyde reductase). (323 aa)
	dgke	Diacylglycerol kinase. (593 aa)
	LOC103460557	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (562 aa)
	LOC103478976	acidPPc domain-containing protein. (271 aa)
	ENSPREP00000005506	Uncharacterized protein. (172 aa)
	mboat2	Membrane bound O-acyltransferase domain containing 2a; Belongs to the membrane-bound acyltransferase family. (496 aa)
	LOC103468776	Phosphatidic acid phosphatase type 2D. (330 aa)
	LOC103479006	Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family. (518 aa)
	glyctk	Glycerate kinase. (524 aa)
	ENSPREP00000007505	PNPLA domain-containing protein. (262 aa)
	lclat1	Lysocardiolipin acyltransferase 1. (376 aa)
	GPAT4	Glycerol-3-phosphate acyltransferase 4. (490 aa)
	LOC103475651	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
	ENSPREP00000013161	FGGY_N domain-containing protein. (144 aa)
	lipg	Lipase, endothelial. (446 aa)
	dgkk	Diacylglycerol kinase. (1090 aa)
	mogat2	Monoacylglycerol O-acyltransferase 2. (252 aa)
	dgat2	Diacylglycerol O-acyltransferase 2. (365 aa)
	LOC103470001	1-acylglycerol-3-phosphate O-acyltransferase 9, like. (446 aa)
	plpp2	Phospholipid phosphatase 2a. (287 aa)
	LOC103459462	Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (316 aa)
	DGKQ	Diacylglycerol kinase. (895 aa)
	LOC103473716	Glycerol-3-phosphate acyltransferase 4. (457 aa)
	LOC103470045	Phospholipid phosphatase 5. (266 aa)
	LOC103463553	Phospholipid phosphatase 2b. (289 aa)
	pnpla2	Patatin-like phospholipase domain containing 2. (489 aa)
	lpin1	Si:ch73-21k16.1. (902 aa)
	DGAT1	O-acyltransferase. (523 aa)
	LOC103462762	Lipin 1. (954 aa)
	LOC103470060	Glycerol-3-phosphate acyltransferase 2, mitochondrial. (800 aa)
	aldh16a1	Aldehyde dehydrogenase 16 family, member A1. (797 aa)
	lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (517 aa)
	LOC103463532	PLAT domain-containing protein. (507 aa)
	mgll	Monoglyceride lipase. (345 aa)
	gla	Alpha-galactosidase. (419 aa)
	akr1a1	Aldo-keto reductase family 1, member A1b (aldehyde reductase). (352 aa)
	dgka	Diacylglycerol kinase. (720 aa)
	aldh9a1	Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family. (505 aa)
	agpat3	1-acylglycerol-3-phosphate O-acyltransferase 3. (376 aa)
	LOC103470110	acidPPc domain-containing protein. (279 aa)
	aldh7a1	Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. (542 aa)
	LOC103474340	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
	LOC103479825	Lipin 2. (906 aa)
	tkfc	Triokinase/FMN cyclase. (583 aa)
	LOC103459750	Patatin-like phospholipase domain containing 3. (473 aa)
	aldh2	Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. (522 aa)
	gk	Uncharacterized protein; Belongs to the FGGY kinase family. (577 aa)
	LOC103467428	PNPLA domain-containing protein. (435 aa)
	agk	Acylglycerol kinase. (423 aa)
	dgkb	Diacylglycerol kinase. (777 aa)
	LOC103473378	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (271 aa)
	plpp3	Phospholipid phosphatase 3. (313 aa)
	LOC103473964	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (506 aa)
	DGKD-2	SAM domain-containing protein. (403 aa)
	agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon). (365 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (818 aa)
	LOC103475773	Monoacylglycerol O-acyltransferase 3b. (326 aa)
	agpat4	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta). (394 aa)
	lipc	Lipase, hepatic a. (501 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGAT1	DGKD-2	ENSPREP00000017869	ENSPREP00000032071	O-acyltransferase.	SAM domain-containing protein.	0.900
DGAT1	DGKQ	ENSPREP00000017869	ENSPREP00000016303	O-acyltransferase.	Diacylglycerol kinase.	0.913
DGAT1	ENSPREP00000007505	ENSPREP00000017869	ENSPREP00000007505	O-acyltransferase.	PNPLA domain-containing protein.	0.695
DGAT1	LOC103459750	ENSPREP00000017869	ENSPREP00000026453	O-acyltransferase.	Patatin-like phospholipase domain containing 3.	0.698
DGAT1	LOC103460557	ENSPREP00000017869	ENSPREP00000004169	O-acyltransferase.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.658
DGAT1	LOC103462762	ENSPREP00000017869	ENSPREP00000017913	O-acyltransferase.	Lipin 1.	0.766
DGAT1	LOC103462875	ENSPREP00000017869	ENSPREP00000000426	O-acyltransferase.	acidPPc domain-containing protein.	0.754
DGAT1	LOC103463553	ENSPREP00000017869	ENSPREP00000017478	O-acyltransferase.	Phospholipid phosphatase 2b.	0.809
DGAT1	LOC103464949	ENSPREP00000017869	ENSPREP00000002058	O-acyltransferase.	Zgc:123305.	0.766
DGAT1	LOC103467428	ENSPREP00000017869	ENSPREP00000029147	O-acyltransferase.	PNPLA domain-containing protein.	0.704
DGAT1	LOC103468776	ENSPREP00000017869	ENSPREP00000006581	O-acyltransferase.	Phosphatidic acid phosphatase type 2D.	0.809
DGAT1	LOC103470045	ENSPREP00000017869	ENSPREP00000017395	O-acyltransferase.	Phospholipid phosphatase 5.	0.935
DGAT1	LOC103470110	ENSPREP00000017869	ENSPREP00000022151	O-acyltransferase.	acidPPc domain-containing protein.	0.809
DGAT1	LOC103473378	ENSPREP00000017869	ENSPREP00000031208	O-acyltransferase.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.474
DGAT1	LOC103473964	ENSPREP00000017869	ENSPREP00000031991	O-acyltransferase.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.658
DGAT1	LOC103475773	ENSPREP00000017869	ENSPREP00000032942	O-acyltransferase.	Monoacylglycerol O-acyltransferase 3b.	0.966
DGAT1	LOC103478976	ENSPREP00000017869	ENSPREP00000005185	O-acyltransferase.	acidPPc domain-containing protein.	0.752
DGAT1	LOC103479825	ENSPREP00000017869	ENSPREP00000023307	O-acyltransferase.	Lipin 2.	0.766
DGAT1	dgat2	ENSPREP00000017869	ENSPREP00000014576	O-acyltransferase.	Diacylglycerol O-acyltransferase 2.	0.971
DGAT1	dgka	ENSPREP00000017869	ENSPREP00000019937	O-acyltransferase.	Diacylglycerol kinase.	0.912