STRINGSTRING
REXO5 REXO5 mdn1 mdn1 rpp30 rpp30 nmd3 nmd3 LOC103472902 LOC103472902 riok2 riok2 bms1 bms1 LOC103478541 LOC103478541 LOC103478532 LOC103478532 dkc1 dkc1 nol6 nol6 wdr43 wdr43 Nhp2 Nhp2 ENSPREP00000008270 ENSPREP00000008270 ENSPREP00000008710 ENSPREP00000008710 gnl2 gnl2 SPATA5 SPATA5 imp3 imp3 LOC103469911 LOC103469911 nob1 nob1 rcl1 rcl1 rexo1 rexo1 rpp40 rpp40 riok1 riok1 nop10 nop10 LOC103477318 LOC103477318 gar1 gar1 utp15 utp15 emg1 emg1 ak6 ak6 utp18 utp18 xrn2 xrn2 utp6 utp6 imp4 imp4 nop58 nop58 rbm28 rbm28 pop7 pop7 nxf1 nxf1 LOC103482453 LOC103482453 LOC103473717 LOC103473717 ENSPREP00000023617 ENSPREP00000023617 nat10 nat10 Heatr1 Heatr1 rexo2 rexo2 wdr36 wdr36 ran ran Rpp38 Rpp38 fbl fbl sbds sbds utp4 utp4 fcf1 fcf1 Wdr3 Wdr3 gtpbp4 gtpbp4 snu13 snu13 pop5 pop5 xpo1 xpo1 POP1 POP1 LOC103465502 LOC103465502 nop56 nop56 xrn1 xrn1 eif6 eif6 gnl3l gnl3l EFL1 EFL1 drosha drosha pop4 pop4 mphosph10 mphosph10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
REXO5RNA exonuclease 5. (806 aa)
mdn1Midasin AAA ATPase 1. (3952 aa)
rpp30Ribonuclease P/MRP 30 subunit. (287 aa)
nmd360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (517 aa)
LOC103472902Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (227 aa)
riok2RIO kinase 2 (yeast). (520 aa)
bms1BMS1 ribosome biogenesis factor. (1311 aa)
LOC103478541Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
LOC103478532Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
dkc1Dyskeratosis congenita 1, dyskerin. (553 aa)
nol6Nucleolar protein 6. (1145 aa)
wdr43WD repeat domain 43. (651 aa)
Nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (117 aa)
ENSPREP00000008270WD_REPEATS_REGION domain-containing protein. (129 aa)
ENSPREP00000008710Ribonuclease P and MRP subunit p25, b. (222 aa)
gnl2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (740 aa)
SPATA5Spermatogenesis associated 5. (904 aa)
imp3IMP U3 small nucleolar ribonucleoprotein 3. (183 aa)
LOC103469911Exonuclease domain-containing protein. (1096 aa)
nob1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (457 aa)
rcl1RNA terminal phosphate cyclase-like 1. (372 aa)
rexo1REX1, RNA exonuclease 1 homolog. (1238 aa)
rpp40Ribonuclease P/MRP 40 subunit. (348 aa)
riok1Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (526 aa)
nop10NOP10 ribonucleoprotein homolog (yeast). (64 aa)
LOC103477318Exportin 1 (CRM1 homolog, yeast) b. (1071 aa)
gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (234 aa)
utp15UTP15 small subunit processome component. (528 aa)
emg1EMG1 N1-specific pseudouridine methyltransferase. (289 aa)
ak6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (173 aa)
utp18WD_REPEATS_REGION domain-containing protein. (533 aa)
xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (943 aa)
utp6UTP6 small subunit processome component. (603 aa)
imp4IMP U3 small nucleolar ribonucleoprotein 4. (291 aa)
nop58NOP58 ribonucleoprotein homolog (yeast). (455 aa)
rbm28RNA binding motif protein 28. (760 aa)
pop7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. (151 aa)
nxf1Zgc:153681. (667 aa)
LOC103482453UTP14C small subunit processome component. (763 aa)
LOC103473717PWP2 small subunit processome component. (914 aa)
ENSPREP00000023617Alba domain-containing protein. (191 aa)
nat10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (955 aa)
Heatr1BP28CT domain-containing protein. (345 aa)
rexo2Small fragment nuclease. (280 aa)
wdr36WD repeat domain 36. (793 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (218 aa)
Rpp38Ribonuclease P/MRP 38 subunit. (278 aa)
fblFibrillarin. (310 aa)
sbdsSBDS ribosome maturation factor. (249 aa)
utp4UTP4 small subunit processome component. (684 aa)
fcf1FCF1 rRNA-processing protein. (197 aa)
Wdr3Uncharacterized protein. (97 aa)
gtpbp4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (604 aa)
snu13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
pop5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (167 aa)
xpo1Exportin 1 (CRM1 homolog, yeast) a. (1066 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (960 aa)
LOC103465502Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (332 aa)
nop56NOP56 ribonucleoprotein homolog. (530 aa)
xrn15'-3' exoribonuclease 1. (1705 aa)
eif6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (255 aa)
gnl3lGuanine nucleotide binding protein-like 3 (nucleolar)-like. (551 aa)
EFL1Elongation factor like GTPase 1. (1106 aa)
droshaDrosha ribonuclease III. (1312 aa)
pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (231 aa)
mphosph10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (665 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.