STRINGSTRING
fbxw7 fbxw7 SMURF2 SMURF2 LOC103477972 LOC103477972 anapc13 anapc13 LOC103466235 LOC103466235 LOC103466236 LOC103466236 itch itch herc3 herc3 fbxw11 fbxw11 LOC103477708 LOC103477708 LOC103459105 LOC103459105 ube2j2 ube2j2 LOC103471315 LOC103471315 prpf19 prpf19 LOC103477709 LOC103477709 aire aire anapc10 anapc10 cdc20 cdc20 anapc11 anapc11 traf6 traf6 syvn1 syvn1 LOC103464541 LOC103464541 socs3 socs3 LOC103471054 LOC103471054 ddb1 ddb1 UBA3 UBA3 LOC103470451 LOC103470451 LOC103462696 LOC103462696 skp1 skp1 ube2b ube2b fbxw8 fbxw8 anapc2 anapc2 cdc16 cdc16 LOC103461355 LOC103461355 cul2 cul2 uba6 uba6 rhobtb2 rhobtb2 ube2z ube2z wwp1 wwp1 LOC103470542 LOC103470542 mgrn1 mgrn1 ube2s ube2s ube2g1 ube2g1 pias4 pias4 ube3c ube3c MID1 MID1 Herc1 Herc1 fancl fancl LOC103458467 LOC103458467 LOC103468942 LOC103468942 UBE2D1 UBE2D1 LOC103466533 LOC103466533 ube2l3 ube2l3 cul1 cul1 LOC103460179 LOC103460179 LOC103471799 LOC103471799 ddb2 ddb2 uba52 uba52 cul4b cul4b ube2n ube2n LOC103463544 LOC103463544 ube2m ube2m ube2a ube2a LOC103465255 LOC103465255 rps27a rps27a cdc27 cdc27 ppil2 ppil2 eloc eloc ube2e1 ube2e1 LOC103471961 LOC103471961 keap1 keap1 LOC103477907 LOC103477907 LOC103476312 LOC103476312 LOC103468522 LOC103468522 LOC103473220 LOC103473220 LOC103464828 LOC103464828 LOC103469522 LOC103469522 anapc7 anapc7 trim37 trim37 ubr5 ubr5 LOC103479391 LOC103479391 birc2 birc2 ube3a ube3a uba2 uba2 LOC103466080 LOC103466080 herc2 herc2 CUL5 CUL5 rchy1 rchy1 ube2ql1 ube2ql1 ercc8 ercc8 ube2w ube2w ube2i ube2i UBE3A UBE3A FZR1 FZR1 rbx1 rbx1 nedd4l nedd4l LOC103465417 LOC103465417 LOC103466094 LOC103466094 LOC103465053 LOC103465053 trip12 trip12 rnf7 rnf7 Birc6 Birc6 smurf1 smurf1 LOC103468487 LOC103468487 stub1 stub1 anapc4 anapc4 LOC103474461 LOC103474461 LOC103467931 LOC103467931 sae1 sae1 siah1 siah1 UBE2O UBE2O anapc5 anapc5 ube2r2 ube2r2 NHLRC1 NHLRC1 det1 det1 huwe1 huwe1 ube4a ube4a brca1 brca1 ube3b ube3b LOC103459783 LOC103459783 LOC103475825 LOC103475825 ELOB ELOB cdc23 cdc23
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbxw7F-box and WD repeat domain containing 7. (847 aa)
SMURF2E3 ubiquitin-protein ligase. (776 aa)
LOC103477972Si:rp71-68n21.9. (727 aa)
anapc13Anaphase promoting complex subunit 13. (74 aa)
LOC103466235HECT domain-containing protein. (976 aa)
LOC103466236HECT domain-containing protein. (1004 aa)
itchE3 ubiquitin-protein ligase. (840 aa)
herc3HECT and RLD domain containing E3 ubiquitin protein ligase 3. (1049 aa)
fbxw11F-box and WD repeat domain containing 11a. (562 aa)
LOC103477708UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
LOC103459105Midline 1. (689 aa)
ube2j2Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast). (277 aa)
LOC103471315Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (204 aa)
prpf19Pre-mRNA processing factor 19. (458 aa)
LOC103477709Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
aireAutoimmune regulator. (496 aa)
anapc10Anaphase promoting complex subunit 10. (184 aa)
cdc20Cell division cycle 20 homolog. (555 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
syvn1Synovial apoptosis inhibitor 1, synoviolin. (435 aa)
LOC103464541Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1012 aa)
socs3Suppressor of cytokine signaling 3. (208 aa)
LOC103471054Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ddb1Damage-specific DNA binding protein 1. (1102 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (462 aa)
LOC103470451Rho related BTB domain containing 4. (734 aa)
LOC103462696Ubiquitin-conjugating enzyme E2Q family member 1. (374 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (107 aa)
ube2bUbiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
fbxw8F-box and WD repeat domain containing 8. (655 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (742 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
LOC103461355Suppressor of cytokine signaling 3a. (165 aa)
cul2Cullin 2; Belongs to the cullin family. (745 aa)
uba6Ubiquitin like modifier activating enzyme 6. (1044 aa)
rhobtb2Rho related BTB domain containing 2a. (720 aa)
ube2zUbiquitin-conjugating enzyme E2Z. (405 aa)
wwp1WW domain containing E3 ubiquitin protein ligase 1. (963 aa)
LOC103470542Ubiquitin-conjugating enzyme E2D 4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
mgrn1Mahogunin, ring finger 1b. (548 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
ube2g1Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
pias4Protein inhibitor of activated STAT, 4a. (509 aa)
ube3cUbiquitin protein ligase E3C. (1078 aa)
MID1Uncharacterized protein. (687 aa)
Herc1Uncharacterized protein. (534 aa)
fanclFA complementation group L. (371 aa)
LOC103458467Kelch-like ECH-associated protein 1a. (590 aa)
LOC103468942Elongin B. (117 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
LOC103466533Protein inhibitor of activated STAT, 1b. (647 aa)
ube2l3Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
LOC103460179Uncharacterized protein. (545 aa)
LOC103471799UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ddb2Damage-specific DNA binding protein 2. (490 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
cul4bCullin 4B; Belongs to the cullin family. (872 aa)
ube2nUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
LOC103463544UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (262 aa)
ube2mUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
ube2aUbiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
LOC103465255Von Hippel-Lindau tumor suppressor. (166 aa)
rps27aRibosomal protein S27a. (156 aa)
cdc27Cell division cycle 27. (803 aa)
ppil2Peptidylprolyl isomerase (cyclophilin)-like 2. (525 aa)
elocElongin C paralog a; Belongs to the SKP1 family. (112 aa)
ube2e1Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (195 aa)
LOC103471961UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa)
keap1Kelch-like ECH-associated protein 1b. (613 aa)
LOC103477907Cbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
LOC103476312Uncharacterized protein. (857 aa)
LOC103468522E3 ubiquitin-protein ligase. (770 aa)
LOC103473220UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC103464828E3 ubiquitin-protein ligase. (869 aa)
LOC103469522UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
trim37Tripartite motif containing 37. (957 aa)
ubr5Ubiquitin protein ligase E3 component n-recognin 5. (2851 aa)
LOC103479391CULLIN_2 domain-containing protein; Belongs to the cullin family. (766 aa)
birc2Baculoviral IAP repeat containing 2. (642 aa)
ube3aUbiquitin protein ligase E3A. (823 aa)
uba2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (599 aa)
LOC103466080UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
herc2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4520 aa)
CUL5Cullin 5; Belongs to the cullin family. (662 aa)
rchy1Uncharacterized protein. (276 aa)
ube2ql1Ubiquitin-conjugating enzyme E2Q family-like 1. (286 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
ube2wUBIQUITIN_CONJUGAT_2 domain-containing protein. (158 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (944 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (470 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1268 aa)
LOC103465417Zgc:175088. (191 aa)
LOC103466094Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (209 aa)
LOC103465053Ubiquitin-like modifier activating enzyme 3. (442 aa)
trip12Thyroid hormone receptor interactor 12. (2062 aa)
rnf7Ring finger protein 7. (111 aa)
Birc6UBIQUITIN_CONJUGAT_2 domain-containing protein. (141 aa)
smurf1E3 ubiquitin-protein ligase. (729 aa)
LOC103468487UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
stub1STIP1 homology and U-Box containing protein 1. (286 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (802 aa)
LOC103474461Cullin 3; Belongs to the cullin family. (767 aa)
LOC103467931Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (768 aa)
sae1SUMO1 activating enzyme subunit 1. (344 aa)
siah1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1351 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
ube2r2Ubiquitin-conjugating enzyme E2R 2; Belongs to the ubiquitin-conjugating enzyme family. (262 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (399 aa)
det1DET1 partner of COP1 E3 ubiquitin ligase. (551 aa)
huwe1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4580 aa)
ube4aUbiquitination factor E4A (UFD2 homolog, yeast). (1027 aa)
brca1Uncharacterized protein. (1344 aa)
ube3bUbiquitin protein ligase E3B. (1029 aa)
LOC103459783Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC103475825Kelch-like family member 13. (679 aa)
ELOBElongin B. (119 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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