STRINGSTRING
asah1 asah1 LOC103481937 LOC103481937 Litaf Litaf LOC103481270 LOC103481270 man2b1 man2b1 LOC103464672 LOC103464672 acp5 acp5 LOC103469312 LOC103469312 LOC103466227 LOC103466227 LOC103464615 LOC103464615 LOC103464614 LOC103464614 slc17a5 slc17a5 lipa lipa LOC103462555 LOC103462555 ppt2 ppt2 atp6ap1 atp6ap1 neu1 neu1 ENSPREP00000003282 ENSPREP00000003282 LOC103472818 LOC103472818 ap4m1 ap4m1 LOC103464892 LOC103464892 LOC103480134 LOC103480134 LOC103477738 LOC103477738 ap4s1 ap4s1 LOC103473483 LOC103473483 LOC103477201 LOC103477201 LOC103482186 LOC103482186 naglu naglu LOC103473528 LOC103473528 LOC103474743 LOC103474743 LOC103471043 LOC103471043 LOC103480104 LOC103480104 hyal1 hyal1 HYAL2 HYAL2 glb1 glb1 LOC103459337 LOC103459337 gaa gaa entpd4 entpd4 cln5 cln5 gns gns laptm4a laptm4a LOC103471866 LOC103471866 gusb gusb cln3 cln3 manba manba ctsh ctsh LOC103468700 LOC103468700 scarb2 scarb2 LOC103472996 LOC103472996 LOC103472433 LOC103472433 ap3s2 ap3s2 HYAL2-2 HYAL2-2 HYAL2-4 HYAL2-4 cltc cltc LOC103460859 LOC103460859 LOC103460860 LOC103460860 LOC103461671 LOC103461671 LOC103473662 LOC103473662 LOC103480138 LOC103480138 LOC103469401 LOC103469401 npc2 npc2 ctso ctso m6pr m6pr LOC103466557 LOC103466557 ppt1 ppt1 hgsnat hgsnat LOC103462835 LOC103462835 ap1s3 ap1s3 LOC103473697 LOC103473697 cltcl1 cltcl1 LOC103472454 LOC103472454 galc galc naga naga LOC103479779 LOC103479779 gla gla LOC103467131 LOC103467131 SLC11A2 SLC11A2 LOC103465990 LOC103465990 ctsz ctsz mcoln1 mcoln1 ap1m2 ap1m2 Ap4e1 Ap4e1 LOC103464156 LOC103464156 smpd1 smpd1 LOC103464155 LOC103464155 sort1 sort1 Gm2a Gm2a arsa arsa abcb9 abcb9 LOC103469107 LOC103469107 sumf1 sumf1 LOC103473209 LOC103473209 LOC103470744 LOC103470744 tpp1 tpp1 atp6v1h atp6v1h LOC103460420 LOC103460420 LOC103460418 LOC103460418 LOC103470745 LOC103470745 gga3 gga3 ctsl ctsl atp6v0b atp6v0b mfsd8 mfsd8 GGA1 GGA1 LOC103479392 LOC103479392 LOC103478192 LOC103478192 LOC103462981 LOC103462981 fuca2 fuca2 npc1 npc1 LOC103479906 LOC103479906 Gba Gba gnptg gnptg LOC103477584 LOC103477584 LOC103467683 LOC103467683 LOC103462946 LOC103462946 nagpa nagpa LOC103468494 LOC103468494 lgmn lgmn LOC103481105 LOC103481105 ap3b1 ap3b1 ARSB ARSB AP1S2 AP1S2 LOC103477640 LOC103477640 LOC103477641 LOC103477641 fuca1 fuca1 arsg arsg idua idua LOC103467973 LOC103467973 ctsb ctsb ctns ctns LOC103468625 LOC103468625 ctsc ctsc LOC103463810 LOC103463810 LOC103467860 LOC103467860 LOC103463064 LOC103463064 lamp1 lamp1 LOC103470281 LOC103470281 ap1b1 ap1b1 LOC103476979 LOC103476979 atp6v0a2 atp6v0a2 LOC103478890 LOC103478890 lamp3 lamp3 gnptab gnptab ap1g1 ap1g1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
asah1N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family. (427 aa)
LOC103481937Uncharacterized protein. (617 aa)
LitafLITAF domain-containing protein. (171 aa)
LOC103481270Si:ch73-12o23.1; Belongs to the glycosyl hydrolase 31 family. (972 aa)
man2b1Alpha-mannosidase. (1029 aa)
LOC103464672Uncharacterized protein. (647 aa)
acp5Tartrate-resistant acid phosphatase type 5. (333 aa)
LOC103469312LITAF domain-containing protein. (198 aa)
LOC103466227Phospholipase A2, group XV. (416 aa)
LOC103464615Hyaluronidase. (498 aa)
LOC103464614Hyaluronidase. (508 aa)
slc17a5Solute carrier family 17 member 5. (484 aa)
lipaLipase; Belongs to the AB hydrolase superfamily. Lipase family. (401 aa)
LOC103462555Carboxypeptidase; Belongs to the peptidase S10 family. (466 aa)
ppt2Palmitoyl-protein thioesterase 2. (301 aa)
atp6ap1ATPase H+ transporting accessory protein 1a. (489 aa)
neu1Neuraminidase 1. (387 aa)
ENSPREP00000003282Si:dkey-192p21.6. (324 aa)
LOC103472818Uncharacterized protein. (366 aa)
ap4m1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (442 aa)
LOC103464892Sortilin. (808 aa)
LOC103480134AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
LOC103477738Zgc:66024. (300 aa)
ap4s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (144 aa)
LOC103473483Uncharacterized protein; Belongs to the CD36 family. (516 aa)
LOC103477201Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (538 aa)
LOC103482186V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
nagluN-acetylglucosaminidase, alpha. (796 aa)
LOC103473528Hyaluronidase. (445 aa)
LOC103474743Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
LOC103471043Cathepsin F; Belongs to the peptidase C1 family. (471 aa)
LOC103480104Si:ch211-212k18.7. (245 aa)
hyal1Hyaluronidase. (457 aa)
HYAL2Hyaluronidase. (528 aa)
glb1Beta-galactosidase. (652 aa)
LOC103459337Nothepsin; Belongs to the peptidase A1 family. (407 aa)
gaaGlucosidase, alpha; acid (Pompe disease, glycogen storage disease type II); Belongs to the glycosyl hydrolase 31 family. (932 aa)
entpd4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (618 aa)
cln5CLN5 intracellular trafficking protein. (335 aa)
gnsN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (528 aa)
laptm4aLysosomal protein transmembrane 4 alpha. (239 aa)
LOC103471866Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (308 aa)
gusbBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (653 aa)
cln3Battenin. (480 aa)
manbaMannosidase, beta A, lysosomal. (890 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (325 aa)
LOC103468700LITAF domain-containing protein. (199 aa)
scarb2Scavenger receptor class B, member 2a; Belongs to the CD36 family. (530 aa)
LOC103472996Si:ch1073-513e17.1. (503 aa)
LOC103472433Lysosomal protein transmembrane 4 beta. (225 aa)
ap3s2Adaptor related protein complex 3 subunit sigma 2. (192 aa)
HYAL2-2Hyaluronidase. (499 aa)
HYAL2-4Hyaluronidase. (495 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1700 aa)
LOC103460859Hyaluronidase. (494 aa)
LOC103460860Hyaluronidase. (446 aa)
LOC103461671Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family. (634 aa)
LOC103473662Scavenger receptor class B, member 2c; Belongs to the CD36 family. (481 aa)
LOC103480138Lysosomal associated membrane protein 1. (253 aa)
LOC103469401V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (826 aa)
npc2Niemann-Pick disease, type C2. (158 aa)
ctsoCathepsin O; Belongs to the peptidase C1 family. (327 aa)
m6prMannose-6-phosphate receptor (cation dependent). (281 aa)
LOC103466557Beta-hexosaminidase. (532 aa)
ppt1Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (388 aa)
hgsnatHeparan-alpha-glucosaminide N-acetyltransferase. (654 aa)
LOC103462835Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (193 aa)
ap1s3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (152 aa)
LOC103473697V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (846 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1696 aa)
LOC103472454Cathepsin S, ortholog 1; Belongs to the peptidase C1 family. (328 aa)
galcGalactosylceramidase b. (668 aa)
nagaAlpha-galactosidase. (430 aa)
LOC103479779AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (447 aa)
glaAlpha-galactosidase. (419 aa)
LOC103467131Hyaluronidase. (537 aa)
SLC11A2Solute carrier family 11 member 2. (588 aa)
LOC103465990Hyaluronidase. (491 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (306 aa)
mcoln1Mucolipin 1b. (567 aa)
ap1m2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (443 aa)
Ap4e1Adaptor related protein complex 4 subunit epsilon 1. (361 aa)
LOC103464156Deoxyribonuclease II beta. (352 aa)
smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (602 aa)
LOC103464155Uncharacterized protein. (245 aa)
sort1Sortilin. (822 aa)
Gm2aGM2 ganglioside activator. (198 aa)
arsaArylsulfatase A. (499 aa)
abcb9ATP-binding cassette, sub-family B (MDR/TAP), member 9. (801 aa)
LOC103469107V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
sumf1Sulfatase modifying factor 1. (355 aa)
LOC103473209N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (518 aa)
LOC103470744Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa)
tpp1Tripeptidyl peptidase I. (557 aa)
atp6v1hV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (451 aa)
LOC103460420Hyaluronidase. (514 aa)
LOC103460418Hyaluronidase. (441 aa)
LOC103470745Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa)
gga3Golgi associated, gamma adaptin ear containing, ARF binding protein 3a. (742 aa)
ctslSi:dkey-26g8.5; Belongs to the peptidase C1 family. (335 aa)
atp6v0bATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
mfsd8Major facilitator superfamily domain containing 8. (507 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (642 aa)
LOC103479392AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (153 aa)
LOC103478192Lysosomal protein transmembrane 4 beta. (220 aa)
LOC103462981Cathepsin D; Belongs to the peptidase A1 family. (399 aa)
fuca2Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (454 aa)
npc1Niemann-Pick disease, type C1. (1277 aa)
LOC103479906Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (407 aa)
GbaGlucosylceramidase. (291 aa)
gnptgN-acetylglucosamine-1-phosphate transferase subunit gamma. (316 aa)
LOC103477584Deoxyribonuclease II, lysosomal. (376 aa)
LOC103467683Mucolipin 1a. (585 aa)
LOC103462946V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
nagpaN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (594 aa)
LOC103468494Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (404 aa)
lgmnLegumain. (437 aa)
LOC103481105V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
ap3b1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1103 aa)
ARSBArylsulfatase B. (523 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (159 aa)
LOC103477640Cathepsin K; Belongs to the peptidase C1 family. (330 aa)
LOC103477641Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family. (337 aa)
fuca1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (447 aa)
arsgArylsulfatase G. (554 aa)
iduaIduronidase alpha-L-. (583 aa)
LOC103467973Solute carrier family 11 member 2. (559 aa)
ctsbCathepsin Bb; Belongs to the peptidase C1 family. (324 aa)
ctnsCystinosin, lysosomal cystine transporter. (419 aa)
LOC103468625LITAF domain-containing protein. (123 aa)
ctscCathepsin C; Belongs to the peptidase C1 family. (453 aa)
LOC103463810Cathepsin 12; Belongs to the peptidase C1 family. (352 aa)
LOC103467860ATPase H+ transporting accessory protein 1b. (446 aa)
LOC103463064Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family. (429 aa)
lamp1Lysosomal associated membrane protein 1a. (409 aa)
LOC103470281Surfactant protein Bb. (352 aa)
ap1b1AP complex subunit beta. (1003 aa)
LOC103476979AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
atp6v0a2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (846 aa)
LOC103478890AP-1 complex subunit gamma. (794 aa)
lamp3Uncharacterized protein. (226 aa)
gnptabN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1210 aa)
ap1g1AP-1 complex subunit gamma. (785 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (22%) [HD]