STRINGSTRING
LOC103477155 LOC103477155 LOC103476211 LOC103476211 PRKCA PRKCA prkaca prkaca LOC103462977 LOC103462977 gja1 gja1 lpar1 lpar1 LOC103457562 LOC103457562 LOC103467752 LOC103467752 GNAS GNAS grm1 grm1 LOC103473464 LOC103473464 LOC103473465 LOC103473465 adcy5 adcy5 prkg2 prkg2 LOC103459902 LOC103459902 LOC103464538 LOC103464538 LOC103468788 LOC103468788 LOC103468785 LOC103468785 gucy1b1 gucy1b1 Itpr3 Itpr3 gucy1a1 gucy1a1 LOC103479562 LOC103479562 sos1 sos1 LOC103475379 LOC103475379 htr2b htr2b cdk1 cdk1 adcy6 adcy6 adcy7 adcy7 GJD2 GJD2 csnk1d csnk1d pdgfa pdgfa LOC103472951 LOC103472951 ADCY9 ADCY9 LOC103478059 LOC103478059 map2k2 map2k2 LOC103474861 LOC103474861 TUBB1 TUBB1 LOC103464384 LOC103464384 LOC103463403 LOC103463403 LOC103479663 LOC103479663 pdgfc pdgfc LOC103465228 LOC103465228 LOC103480397 LOC103480397 LOC103481184 LOC103481184 EGFR EGFR map2k1 map2k1 LOC103463573 LOC103463573 SRC SRC LOC103461629 LOC103461629 ENSPREP00000016407 ENSPREP00000016407 LOC103478370 LOC103478370 LOC103461628 LOC103461628 TUBA4A TUBA4A LOC103463549 LOC103463549 LOC103475526 LOC103475526 mapk1 mapk1 tubb4b tubb4b ENSPREP00000019921 ENSPREP00000019921 LOC103469088 LOC103469088 LOC103476798 LOC103476798 prkacb prkacb LOC103475018 LOC103475018 tuba4a tuba4a LOC103467178 LOC103467178 Map3k2 Map3k2 grb2 grb2 LOC103469111 LOC103469111 LOC103466442 LOC103466442 LOC103465353 LOC103465353 LOC103473792 LOC103473792 LOC103477881 LOC103477881 LOC103458356 LOC103458356 Plcb1 Plcb1 LOC103466076 LOC103466076 egfr egfr sos2 sos2 itpr2 itpr2 kras kras adcy3 adcy3 PRKCB PRKCB hras hras ENSPREP00000028731 ENSPREP00000028731 pdgfra pdgfra LOC103467923 LOC103467923 LOC103470235 LOC103470235 plcb3 plcb3 ENSPREP00000030008 ENSPREP00000030008 grm5 grm5 adcy8 adcy8 pdgfd pdgfd GUCY1A2 GUCY1A2 LOC103467856 LOC103467856 htr2a htr2a LOC103465516 LOC103465516 PLCB2 PLCB2 LOC103467316 LOC103467316 LOC103459297 LOC103459297 LOC103467815 LOC103467815 drd2 drd2 adrb1 adrb1 LOC103462420 LOC103462420 mapk7 mapk7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103477155Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (560 aa)
LOC103476211Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (229 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
prkacaUncharacterized protein; Belongs to the protein kinase superfamily. (327 aa)
LOC103462977Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (387 aa)
lpar1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa)
LOC103457562Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1185 aa)
LOC103467752Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (476 aa)
GNASGNAS complex locus. (379 aa)
grm1Glutamate receptor, metabotropic 1a. (1157 aa)
LOC103473464Guanine nucleotide binding protein (G protein), alpha 14. (351 aa)
LOC103473465G protein subunit alpha q. (359 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
prkg2cGMP-dependent protein kinase. (792 aa)
LOC103459902Uncharacterized protein. (1039 aa)
LOC103464538Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (355 aa)
LOC103468788Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
LOC103468785Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
gucy1b1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (621 aa)
Itpr3MIR domain-containing protein. (185 aa)
gucy1a1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (678 aa)
LOC103479562Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
sos1Son of sevenless homolog 1 (Drosophila). (1138 aa)
LOC103475379Dopamine receptor D1b; Belongs to the G-protein coupled receptor 1 family. (464 aa)
htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (466 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (308 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1172 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
GJD2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (304 aa)
csnk1dCasein kinase 1, delta b; Belongs to the protein kinase superfamily. (389 aa)
pdgfaPlatelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (228 aa)
LOC103472951Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1439 aa)
LOC103478059Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC103474861Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (306 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (358 aa)
LOC103464384GNAS complex locus. (315 aa)
LOC103463403Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1126 aa)
LOC103479663Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (361 aa)
LOC103465228Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
LOC1034803975-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1. (553 aa)
LOC103481184Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
EGFRReceptor protein-tyrosine kinase. (1135 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
LOC103463573Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
SRCTyrosine-protein kinase. (569 aa)
LOC103461629Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
ENSPREP00000016407Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (337 aa)
LOC103478370Adenylate cyclase 2a; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (847 aa)
LOC103461628Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (460 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (465 aa)
LOC103463549Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
LOC103475526Glutamate receptor, metabotropic 5a. (1192 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
tubb4bTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ENSPREP00000019921Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (495 aa)
LOC103469088Zgc:55558. (191 aa)
LOC103476798Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (460 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
LOC103475018Tubulin domain-containing protein. (113 aa)
tuba4aTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC103467178Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (303 aa)
Map3k2Protein kinase domain-containing protein. (105 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC103469111Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (367 aa)
LOC103466442Tight junction protein 1b; Belongs to the MAGUK family. (1954 aa)
LOC103465353Inositol 1,4,5-trisphosphate receptor, type 1a. (2685 aa)
LOC103473792Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC103477881Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (491 aa)
LOC103458356Glutamate receptor, metabotropic 1b. (1184 aa)
Plcb1Uncharacterized protein. (33 aa)
LOC103466076Uncharacterized protein. (354 aa)
egfrReceptor protein-tyrosine kinase. (1196 aa)
sos2Son of sevenless homolog 2 (Drosophila). (645 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2699 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1121 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
ENSPREP00000028731Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
pdgfraPlatelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1457 aa)
LOC103467923Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (290 aa)
LOC103470235Uncharacterized protein. (359 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
ENSPREP00000030008Si:dkey-121j17.5; Belongs to the protein kinase superfamily. (319 aa)
grm5Glutamate receptor, metabotropic 5b. (1254 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1239 aa)
pdgfdPlatelet derived growth factor d. (359 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (807 aa)
LOC103467856Tyrosine-protein kinase. (542 aa)
htr2a5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (496 aa)
LOC103465516Inositol 1,4,5-trisphosphate receptor, type 1b. (2726 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1272 aa)
LOC103467316Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1179 aa)
LOC103459297Uncharacterized protein. (285 aa)
LOC103467815Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
drd2Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family. (467 aa)
adrb1Adrenoceptor beta 1. (397 aa)
LOC103462420Tight junction protein 1a; Belongs to the MAGUK family. (1693 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1073 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (12%) [HD]