STRINGSTRING
LOC103477731 LOC103477731 PRKCA PRKCA prkaca prkaca LOC103462977 LOC103462977 gnrh1 gnrh1 CACNA1D CACNA1D LOC103457562 LOC103457562 GNAS GNAS LOC103472837 LOC103472837 LOC103466877 LOC103466877 LOC103464907 LOC103464907 LOC103467718 LOC103467718 LOC103473464 LOC103473464 LOC103473465 LOC103473465 adcy5 adcy5 LOC103459892 LOC103459892 LOC103471253 LOC103471253 jun jun CDC42 CDC42 LOC103462200 LOC103462200 egr1 egr1 fshb fshb LOC103468785 LOC103468785 LOC103481524 LOC103481524 LOC103475992 LOC103475992 Itpr3 Itpr3 LOC103462176 LOC103462176 LOC103476626 LOC103476626 LOC103471128 LOC103471128 sos1 sos1 mmp2 mmp2 GNRHR GNRHR adcy6 adcy6 adcy7 adcy7 LOC103481589 LOC103481589 ADCY9 ADCY9 LOC103465120 LOC103465120 pla2g4c pla2g4c map2k2 map2k2 LOC103464384 LOC103464384 pla2g4a pla2g4a LOC103467000 LOC103467000 LOC103463403 LOC103463403 LOC103479663 LOC103479663 LOC103469495 LOC103469495 LOC103481184 LOC103481184 EGFR EGFR map2k1 map2k1 calm2 calm2 SRC SRC LOC103478370 LOC103478370 LOC103475221 LOC103475221 LOC103477991 LOC103477991 Elk1 Elk1 LOC103463549 LOC103463549 ENSPREP00000019402 ENSPREP00000019402 mapk1 mapk1 LOC103469088 LOC103469088 prkacb prkacb LOC103480952 LOC103480952 Map3k2 Map3k2 grb2 grb2 LOC103469111 LOC103469111 camk2b camk2b LOC103465353 LOC103465353 ENSPREP00000023275 ENSPREP00000023275 Plcb1 Plcb1 egfr egfr map2k4 map2k4 sos2 sos2 itpr2 itpr2 kras kras adcy3 adcy3 LOC103468496 LOC103468496 mapk10 mapk10 PRKCB PRKCB hras hras LOC103470235 LOC103470235 plcb3 plcb3 gnrh2 gnrh2 adcy8 adcy8 cga cga LOC103467856 LOC103467856 LOC103466203 LOC103466203 LOC103456566 LOC103456566 LOC103465516 LOC103465516 mapk8 mapk8 LOC103480087 LOC103480087 PLCB2 PLCB2 LOC103478877 LOC103478877 LOC103467316 LOC103467316 LOC103467285 LOC103467285 map3k4 map3k4 mapk7 mapk7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103477731Activating transcription factor 4a. (424 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
prkacaUncharacterized protein; Belongs to the protein kinase superfamily. (327 aa)
LOC103462977Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
gnrh1Uncharacterized protein. (94 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2236 aa)
LOC103457562Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1185 aa)
GNASGNAS complex locus. (379 aa)
LOC103472837Uncharacterized protein. (196 aa)
LOC103466877Mitogen-activated protein kinase. (364 aa)
LOC103464907Mitogen-activated protein kinase. (363 aa)
LOC103467718Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2073 aa)
LOC103473464Guanine nucleotide binding protein (G protein), alpha 14. (351 aa)
LOC103473465G protein subunit alpha q. (359 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LOC103459892Calcium/calmodulin-dependent protein kinase II alpha. (502 aa)
LOC103471253Mitogen-activated protein kinase. (420 aa)
junBZIP domain-containing protein; Belongs to the bZIP family. (322 aa)
CDC42Cell division cycle 42. (191 aa)
LOC103462200G_PROTEIN_RECEP_F1_2 domain-containing protein. (424 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (511 aa)
fshbCys_knot domain-containing protein. (113 aa)
LOC103468785Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
LOC103481524Protein kinase domain-containing protein. (616 aa)
LOC103475992Matrix metallopeptidase 14a (membrane-inserted). (562 aa)
Itpr3MIR domain-containing protein. (185 aa)
LOC103462176G_PROTEIN_RECEP_F1_2 domain-containing protein. (465 aa)
LOC103476626Luteinizing hormone, beta polypeptide. (147 aa)
LOC103471128Heparin-binding EGF-like growth factor a. (236 aa)
sos1Son of sevenless homolog 1 (Drosophila). (1138 aa)
mmp2Matrix metallopeptidase 2. (657 aa)
GNRHRGonadotropin releasing hormone receptor. (394 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1172 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
LOC103481589Mitogen-activated protein kinase kinase 6. (405 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1439 aa)
LOC103465120Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2102 aa)
pla2g4cZgc:101699. (580 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC103464384GNAS complex locus. (315 aa)
pla2g4aPhospholipase A2. (749 aa)
LOC103467000Mitogen-activated protein kinase. (366 aa)
LOC103463403Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1126 aa)
LOC103479663Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
LOC103469495Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2. (553 aa)
LOC103481184Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
EGFRReceptor protein-tyrosine kinase. (1135 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
calm2Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
SRCTyrosine-protein kinase. (569 aa)
LOC103478370Adenylate cyclase 2a; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (847 aa)
LOC103475221Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (942 aa)
LOC103477991Uncharacterized protein. (191 aa)
Elk1ETS domain-containing protein. (135 aa)
LOC103463549Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
ENSPREP00000019402Protein kinase domain-containing protein. (201 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
LOC103469088Zgc:55558. (191 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
LOC103480952Uncharacterized protein. (391 aa)
Map3k2Protein kinase domain-containing protein. (105 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC103469111Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (367 aa)
camk2bCalcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (539 aa)
LOC103465353Inositol 1,4,5-trisphosphate receptor, type 1a. (2685 aa)
ENSPREP00000023275G_PROTEIN_RECEP_F1_2 domain-containing protein. (90 aa)
Plcb1Uncharacterized protein. (33 aa)
egfrReceptor protein-tyrosine kinase. (1196 aa)
map2k4Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
sos2Son of sevenless homolog 2 (Drosophila). (645 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2699 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1121 aa)
LOC103468496Activating transcription factor 4b. (430 aa)
mapk10Mitogen-activated protein kinase. (426 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC103470235Uncharacterized protein. (359 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
gnrh2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (93 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1239 aa)
cgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (127 aa)
LOC103467856Tyrosine-protein kinase. (542 aa)
LOC103466203Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
LOC103456566Mitogen-activated protein kinase kinase kinase 22. (618 aa)
LOC103465516Inositol 1,4,5-trisphosphate receptor, type 1b. (2726 aa)
mapk8Mitogen-activated protein kinase. (426 aa)
LOC103480087Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1; Belongs to the protein kinase superfamily. (499 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1272 aa)
LOC103478877Matrix metallopeptidase 14b (membrane-inserted). (616 aa)
LOC103467316Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1179 aa)
LOC103467285Mitogen-activated protein kinase. (347 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1587 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1073 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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