(99 nodes) Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102229533	Ribosomal protein L36A; Belongs to the eukaryotic ribosomal protein eL42 family. (106 aa)
	rpl14	Ribosomal protein L14. (136 aa)
	eif5b	Eukaryotic translation initiation factor 5B. (885 aa)
	Rps25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (96 aa)
	rps7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
	rpl18a	60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family. (176 aa)
	RPL5	Ribosomal protein L5b. (281 aa)
	LOC102231060	NAD(P)-bd_dom domain-containing protein. (214 aa)
	rpl13	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (211 aa)
	LOC102224586	40S ribosomal protein S27. (86 aa)
	Uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (355 aa)
	LOC102218016	Ribosomal protein L5. (298 aa)
	LOC102235575	Ribosomal protein L22. (130 aa)
	rpl10	Ribosomal protein L10. (179 aa)
	LOC102228859	High mobility group nucleosome binding domain 6. (97 aa)
	rps15a	Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family. (164 aa)
	rpl37	Ribosomal protein L37; Binds to the 23S rRNA. (97 aa)
	RPL27A	Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family. (148 aa)
	rpl28	Ribosomal protein L28. (137 aa)
	rps6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (256 aa)
	rps14	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)
	rpl23	Uncharacterized protein; Belongs to the universal ribosomal protein uL14 family. (140 aa)
	rpl36	60S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (141 aa)
	rps3a	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (266 aa)
	LOC102236045	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (197 aa)
	rpl7l1	Ribosomal protein L7-like 1. (247 aa)
	rps11	Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (161 aa)
	LOC102219960	Ribosomal protein L26. (190 aa)
	rpl7	Ribosomal protein L7. (245 aa)
	LOC102231214	Ribosomal protein, large P2; Belongs to the eukaryotic ribosomal protein P1/P2 family. (116 aa)
	rpl22l1	Ribosomal protein L22-like 1. (129 aa)
	rps9	Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
	rps13	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	rpl31	Ribosomal protein L31. (124 aa)
	rsad1	Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (439 aa)
	Rpl39	Ribosomal protein L39. (58 aa)
	rps15	40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa)
	M4AHM8_XIPMA	Ribosomal protein S28. (53 aa)
	rpl3	Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family. (403 aa)
	ifi35	Interferon-induced protein 35. (372 aa)
	rpl35a	Ribosomal protein L35a. (110 aa)
	rps5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (203 aa)
	rps4x	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	rps2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (279 aa)
	rps8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (204 aa)
	RPS19	Ribosomal protein S19. (154 aa)
	rplp1	Ribosomal protein, large, P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa)
	LOC102232912	40S ribosomal protein S27. (191 aa)
	rpl11	Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa)
	rpl15	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
	wdr31	WD repeat domain 31. (358 aa)
	rpl8	Ribosomal protein L8. (257 aa)
	rplp0	Ribosomal protein, large, P0. (252 aa)
	M4AZB2_XIPMA	Uncharacterized protein. (56 aa)
	rps26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (126 aa)
	rpl21	Ribosomal protein L21. (182 aa)
	rack1	Receptor for activated C kinase 1. (317 aa)
	LOC102235702	Ribosomal protein S17. (174 aa)
	rpl24	Ribosomal protein L24. (157 aa)
	rpl37a	Ribosomal protein L37a. (92 aa)
	rpl17	Ribosomal protein L17; Belongs to the universal ribosomal protein uL22 family. (220 aa)
	rpl23a	Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family. (176 aa)
	rpl30	Ribosomal protein L30. (121 aa)
	rps10	Ribosomal protein S10. (166 aa)
	rps3	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (245 aa)
	rpl10a	Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. (216 aa)
	rps18	Ribosomal protein S18; Belongs to the universal ribosomal protein uS13 family. (152 aa)
	rpsa	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (310 aa)
	LOC102237476	Eukaryotic translation initiation factor 5A. (159 aa)
	rpl13a	Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family. (205 aa)
	rsrc1	Arginine and serine rich coiled-coil 1. (320 aa)
	rpl27	Ribosomal protein L27. (143 aa)
	RPL19	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (223 aa)
	RPS29	Ribosomal protein S29. (72 aa)
	LOC102225777	Ribosomal protein S19. (146 aa)
	LOC102225077	40S ribosomal protein S27. (197 aa)
	aknad1	Uncharacterized protein. (1232 aa)
	LOC102224127	Tr-type G domain-containing protein. (858 aa)
	rpl6	Ribosomal protein L6. (259 aa)
	rpl9	Ribosomal protein L9. (193 aa)
	rpl12	Ribosomal protein L12; Belongs to the universal ribosomal protein uL11 family. (165 aa)
	rps21	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (83 aa)
	RPS20	Ribosomal protein S20. (119 aa)
	rpl4	Ribosomal protein L4. (368 aa)
	LOC102226026	Ribosomal protein L22. (172 aa)
	RPS17	Ribosomal protein S17. (134 aa)
	RPL3L	Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family. (257 aa)
	Mrnip	Uncharacterized protein. (65 aa)
	rps24	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (201 aa)
	RPL7A	Ribosomal protein L7a. (266 aa)
	rps16	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	rpl38	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (124 aa)
	rpl29	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (64 aa)
	rpl32	Ribosomal protein L32. (135 aa)
	LOC102221193	Eukaryotic translation elongation factor 2b. (884 aa)
	rps23	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	rps12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (154 aa)
	rpl18	Ribosomal protein L18. (188 aa)
	rpl35	Ribosomal protein L35. (124 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102218016	LOC102219960	ENSXMAP00000004109	ENSXMAP00000010307	Ribosomal protein L5.	Ribosomal protein L26.	0.996
LOC102218016	LOC102221193	ENSXMAP00000004109	ENSXMAP00000037333	Ribosomal protein L5.	Eukaryotic translation elongation factor 2b.	0.941
LOC102218016	LOC102224127	ENSXMAP00000004109	ENSXMAP00000030988	Ribosomal protein L5.	Tr-type G domain-containing protein.	0.941
LOC102218016	LOC102224586	ENSXMAP00000004109	ENSXMAP00000003396	Ribosomal protein L5.	40S ribosomal protein S27.	0.897
LOC102218016	LOC102225077	ENSXMAP00000004109	ENSXMAP00000030543	Ribosomal protein L5.	40S ribosomal protein S27.	0.951
LOC102218016	LOC102225777	ENSXMAP00000004109	ENSXMAP00000030182	Ribosomal protein L5.	Ribosomal protein S19.	0.963
LOC102218016	LOC102226026	ENSXMAP00000004109	ENSXMAP00000033844	Ribosomal protein L5.	Ribosomal protein L22.	0.935
LOC102218016	LOC102228859	ENSXMAP00000004109	ENSXMAP00000004843	Ribosomal protein L5.	High mobility group nucleosome binding domain 6.	0.971
LOC102218016	LOC102229533	ENSXMAP00000004109	ENSXMAP00000000303	Ribosomal protein L5.	Ribosomal protein L36A; Belongs to the eukaryotic ribosomal protein eL42 family.	0.994
LOC102218016	LOC102231060	ENSXMAP00000004109	ENSXMAP00000003161	Ribosomal protein L5.	NAD(P)-bd_dom domain-containing protein.	0.860
LOC102218016	LOC102231214	ENSXMAP00000004109	ENSXMAP00000011047	Ribosomal protein L5.	Ribosomal protein, large P2; Belongs to the eukaryotic ribosomal protein P1/P2 family.	0.994
LOC102218016	LOC102232912	ENSXMAP00000004109	ENSXMAP00000016111	Ribosomal protein L5.	40S ribosomal protein S27.	0.951
LOC102218016	LOC102235575	ENSXMAP00000004109	ENSXMAP00000004595	Ribosomal protein L5.	Ribosomal protein L22.	0.935
LOC102218016	LOC102235702	ENSXMAP00000004109	ENSXMAP00000022395	Ribosomal protein L5.	Ribosomal protein S17.	0.923
LOC102218016	LOC102236045	ENSXMAP00000004109	ENSXMAP00000008491	Ribosomal protein L5.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.983
LOC102218016	LOC102237476	ENSXMAP00000004109	ENSXMAP00000027281	Ribosomal protein L5.	Eukaryotic translation initiation factor 5A.	0.900
LOC102218016	M4AHM8_XIPMA	ENSXMAP00000004109	ENSXMAP00000013972	Ribosomal protein L5.	Ribosomal protein S28.	0.990
LOC102218016	M4AZB2_XIPMA	ENSXMAP00000004109	ENSXMAP00000019807	Ribosomal protein L5.	Uncharacterized protein.	0.963
LOC102218016	Mrnip	ENSXMAP00000004109	ENSXMAP00000034636	Ribosomal protein L5.	Uncharacterized protein.	0.962
LOC102218016	RPL19	ENSXMAP00000004109	ENSXMAP00000028635	Ribosomal protein L5.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.983