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ACO2 ACO2 pdhx pdhx LOC102229547 LOC102229547 idh3b idh3b LOC102226896 LOC102226896 LOC102234452 LOC102234452 GOT1 GOT1 sdhc sdhc bckdhb bckdhb idh1 idh1 bckdha bckdha sucla2 sucla2 pdhb pdhb ACLY ACLY sdha sdha LOC102230038 LOC102230038 LOC102228484 LOC102228484 got2 got2 dbt dbt dlat dlat GCDH GCDH LOC102237188 LOC102237188 LOC102223039 LOC102223039 dld dld ddo ddo nit2 nit2 SDHB SDHB IDH2 IDH2 ogdh ogdh mdh2 mdh2 Fh Fh aco1 aco1 dhtkd1 dhtkd1 gpt gpt idh3g idh3g suclg1 suclg1 pdha1 pdha1 LOC102230331 LOC102230331 mdh1 mdh1 got1 got1 OGDH OGDH txnrd2 txnrd2 LOC102227603 LOC102227603 LOC102220845 LOC102220845 DLST DLST LOC102235446 LOC102235446 suclg2 suclg2 cs cs LOC102220855 LOC102220855 idh3a idh3a sdhd sdhd LOC102234273 LOC102234273
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
LOC102229547Aminotran_1_2 domain-containing protein. (502 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
LOC102226896Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
LOC102234452Malate dehydrogenase. (333 aa)
GOT1Aspartate aminotransferase. (410 aa)
sdhcSuccinate dehydrogenase complex, subunit C, integral membrane protein. (169 aa)
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (387 aa)
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (447 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (478 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1091 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
LOC102230038Thioredoxin reductase 3. (600 aa)
LOC102228484ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1101 aa)
got2Aspartate aminotransferase. (428 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (508 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (645 aa)
GCDHGlutaryl-CoA dehydrogenase b. (440 aa)
LOC102237188Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (279 aa)
LOC102223039Uncharacterized protein. (609 aa)
dldDihydrolipoyl dehydrogenase. (508 aa)
ddoZgc:172341. (337 aa)
nit2Nitrilase family, member 2. (280 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (283 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (454 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1022 aa)
mdh2Malate dehydrogenase. (337 aa)
FhFumarate hydratase. (494 aa)
aco1Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (894 aa)
dhtkd1Dehydrogenase E1 and transketolase domain containing 1. (924 aa)
gptSi:ch211-217a12.1. (491 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (396 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (455 aa)
LOC102230331Aminotran_1_2 domain-containing protein. (446 aa)
mdh1Malate dehydrogenase. (350 aa)
got1Aspartate aminotransferase. (410 aa)
OGDHOxoglutarate dehydrogenase. (1036 aa)
txnrd2Thioredoxin reductase 2, tandem duplicate 1. (512 aa)
LOC102227603Aminotran_1_2 domain-containing protein. (479 aa)
LOC102220845Dihydrolipoamide S-succinyltransferase. (539 aa)
DLSTDihydrolipoamide S-succinyltransferase. (430 aa)
LOC102235446Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
csCitrate synthase; Belongs to the citrate synthase family. (469 aa)
LOC102220855Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (562 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (157 aa)
LOC102234273Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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