(28 nodes) One carbon pool by folate, and De novo IMP biosynthetic process network (Xiphophorus maculatus)

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Your Input:
	atic	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (540 aa)
	tyms	Thymidylate synthetase. (321 aa)
	adsl	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (481 aa)
	gart	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1082 aa)
	mtfmt	Mitochondrial methionyl-tRNA formyltransferase. (382 aa)
	aldh1l2	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
	Ftcd	Formimidoyltransferase cyclodeaminase. (323 aa)
	LOC102217529	Serine hydroxymethyltransferase 2 (mitochondrial). (501 aa)
	M4A5C7_XIPMA	Uncharacterized protein. (213 aa)
	LOC102226379	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (348 aa)
	LOC102236450	AIRC domain-containing protein. (1012 aa)
	LOC102233976	Uncharacterized protein. (345 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (531 aa)
	LOC102237950	Zgc:153031. (198 aa)
	amt	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (415 aa)
	mthfs	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (199 aa)
	mthfd1l	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (974 aa)
	fam107b	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (175 aa)
	fpgs	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (576 aa)
	dalrd3	DALR anticodon binding domain containing 3. (666 aa)
	mthfd1	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (934 aa)
	LOC102235454	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (865 aa)
	iba57	Iron-sulfur cluster assembly factor IBA57. (366 aa)
	dhfr	Dihydrofolate reductase. (208 aa)
	LOC102224598	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (174 aa)
	gldc	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1062 aa)
	shmt1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (521 aa)
	ppat	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ftcd	LOC102217529	ENSXMAP00000005977	ENSXMAP00000006163	Formimidoyltransferase cyclodeaminase.	Serine hydroxymethyltransferase 2 (mitochondrial).	0.927
Ftcd	LOC102224598	ENSXMAP00000005977	ENSXMAP00000032777	Formimidoyltransferase cyclodeaminase.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.448
Ftcd	LOC102226379	ENSXMAP00000005977	ENSXMAP00000010289	Formimidoyltransferase cyclodeaminase.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.978
Ftcd	LOC102233976	ENSXMAP00000005977	ENSXMAP00000017777	Formimidoyltransferase cyclodeaminase.	Uncharacterized protein.	0.978
Ftcd	LOC102235454	ENSXMAP00000005977	ENSXMAP00000028547	Formimidoyltransferase cyclodeaminase.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.914
Ftcd	LOC102237950	ENSXMAP00000005977	ENSXMAP00000019334	Formimidoyltransferase cyclodeaminase.	Zgc:153031.	0.917
Ftcd	M4A5C7_XIPMA	ENSXMAP00000005977	ENSXMAP00000009671	Formimidoyltransferase cyclodeaminase.	Uncharacterized protein.	0.704
Ftcd	SHMT2	ENSXMAP00000005977	ENSXMAP00000019090	Formimidoyltransferase cyclodeaminase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.926
Ftcd	aldh1l2	ENSXMAP00000005977	ENSXMAP00000005318	Formimidoyltransferase cyclodeaminase.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.914
Ftcd	amt	ENSXMAP00000005977	ENSXMAP00000019368	Formimidoyltransferase cyclodeaminase.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.933
Ftcd	dhfr	ENSXMAP00000005977	ENSXMAP00000032115	Formimidoyltransferase cyclodeaminase.	Dihydrofolate reductase.	0.920
Ftcd	fam107b	ENSXMAP00000005977	ENSXMAP00000021491	Formimidoyltransferase cyclodeaminase.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.448
Ftcd	gart	ENSXMAP00000005977	ENSXMAP00000002890	Formimidoyltransferase cyclodeaminase.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.994
Ftcd	mtfmt	ENSXMAP00000005977	ENSXMAP00000003981	Formimidoyltransferase cyclodeaminase.	Mitochondrial methionyl-tRNA formyltransferase.	0.939
Ftcd	mthfd1	ENSXMAP00000005977	ENSXMAP00000027389	Formimidoyltransferase cyclodeaminase.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.	0.969
Ftcd	mthfd1l	ENSXMAP00000005977	ENSXMAP00000020818	Formimidoyltransferase cyclodeaminase.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.969
Ftcd	mthfs	ENSXMAP00000005977	ENSXMAP00000020056	Formimidoyltransferase cyclodeaminase.	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.978
Ftcd	shmt1	ENSXMAP00000005977	ENSXMAP00000037317	Formimidoyltransferase cyclodeaminase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.927
LOC102217529	Ftcd	ENSXMAP00000006163	ENSXMAP00000005977	Serine hydroxymethyltransferase 2 (mitochondrial).	Formimidoyltransferase cyclodeaminase.	0.927
LOC102217529	LOC102224598	ENSXMAP00000006163	ENSXMAP00000032777	Serine hydroxymethyltransferase 2 (mitochondrial).	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.980