(23 nodes) Protein import into peroxisome matrix, and Peptidase S1C network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pex1	Peroxisomal biogenesis factor 1. (1239 aa)
	scp2	Sterol carrier protein 2b. (137 aa)
	LOC102223508	Peroxisomal biogenesis factor 5-like b. (498 aa)
	pex7	Peroxisomal biogenesis factor 7. (349 aa)
	pex10	Peroxisomal biogenesis factor 10. (323 aa)
	lonp2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (841 aa)
	pex13	Peroxisomal biogenesis factor 13. (426 aa)
	fam185a	Family with sequence similarity 185 member A. (389 aa)
	LOC102226285	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (541 aa)
	pex12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (347 aa)
	htra2	Si:dkey-33c12.12. (445 aa)
	htra1	HtrA serine peptidase 1b. (476 aa)
	pex5l	Peroxisomal biogenesis factor 5-like a. (621 aa)
	LOC102218195	HtrA serine peptidase 1a. (475 aa)
	tysnd1	Trypsin domain containing 1. (516 aa)
	eci2	Enoyl-CoA delta isomerase 2. (397 aa)
	hsdl2	Hydroxysteroid dehydrogenase like 2. (417 aa)
	pex6	Uncharacterized protein. (1102 aa)
	pex2	Peroxisomal biogenesis factor 2. (332 aa)
	pex14	Peroxisomal biogenesis factor 14. (374 aa)
	pex5	Peroxisomal biogenesis factor 5. (677 aa)
	amacr	Alpha-methylacyl-CoA racemase. (382 aa)
	phyh	Phytanoyl-CoA 2-hydroxylase. (336 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102218195	LOC102223508	ENSXMAP00000018387	ENSXMAP00000004281	HtrA serine peptidase 1a.	Peroxisomal biogenesis factor 5-like b.	0.529
LOC102218195	LOC102226285	ENSXMAP00000018387	ENSXMAP00000010580	HtrA serine peptidase 1a.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.960
LOC102218195	eci2	ENSXMAP00000018387	ENSXMAP00000022229	HtrA serine peptidase 1a.	Enoyl-CoA delta isomerase 2.	0.693
LOC102218195	fam185a	ENSXMAP00000018387	ENSXMAP00000009135	HtrA serine peptidase 1a.	Family with sequence similarity 185 member A.	0.475
LOC102218195	hsdl2	ENSXMAP00000018387	ENSXMAP00000025364	HtrA serine peptidase 1a.	Hydroxysteroid dehydrogenase like 2.	0.681
LOC102218195	lonp2	ENSXMAP00000018387	ENSXMAP00000006426	HtrA serine peptidase 1a.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.493
LOC102218195	pex10	ENSXMAP00000018387	ENSXMAP00000004882	HtrA serine peptidase 1a.	Peroxisomal biogenesis factor 10.	0.557
LOC102218195	pex12	ENSXMAP00000018387	ENSXMAP00000010875	HtrA serine peptidase 1a.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.482
LOC102218195	pex13	ENSXMAP00000018387	ENSXMAP00000007397	HtrA serine peptidase 1a.	Peroxisomal biogenesis factor 13.	0.497
LOC102218195	pex14	ENSXMAP00000018387	ENSXMAP00000027838	HtrA serine peptidase 1a.	Peroxisomal biogenesis factor 14.	0.475
LOC102218195	pex5	ENSXMAP00000018387	ENSXMAP00000032083	HtrA serine peptidase 1a.	Peroxisomal biogenesis factor 5.	0.529
LOC102218195	pex5l	ENSXMAP00000018387	ENSXMAP00000018367	HtrA serine peptidase 1a.	Peroxisomal biogenesis factor 5-like a.	0.529
LOC102218195	scp2	ENSXMAP00000018387	ENSXMAP00000003119	HtrA serine peptidase 1a.	Sterol carrier protein 2b.	0.960
LOC102223508	LOC102218195	ENSXMAP00000004281	ENSXMAP00000018387	Peroxisomal biogenesis factor 5-like b.	HtrA serine peptidase 1a.	0.529
LOC102223508	LOC102226285	ENSXMAP00000004281	ENSXMAP00000010580	Peroxisomal biogenesis factor 5-like b.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.997
LOC102223508	amacr	ENSXMAP00000004281	ENSXMAP00000032977	Peroxisomal biogenesis factor 5-like b.	Alpha-methylacyl-CoA racemase.	0.562
LOC102223508	eci2	ENSXMAP00000004281	ENSXMAP00000022229	Peroxisomal biogenesis factor 5-like b.	Enoyl-CoA delta isomerase 2.	0.973
LOC102223508	fam185a	ENSXMAP00000004281	ENSXMAP00000009135	Peroxisomal biogenesis factor 5-like b.	Family with sequence similarity 185 member A.	0.866
LOC102223508	hsdl2	ENSXMAP00000004281	ENSXMAP00000025364	Peroxisomal biogenesis factor 5-like b.	Hydroxysteroid dehydrogenase like 2.	0.872
LOC102223508	htra1	ENSXMAP00000004281	ENSXMAP00000014303	Peroxisomal biogenesis factor 5-like b.	HtrA serine peptidase 1b.	0.529