STRINGSTRING
LOC102224681 LOC102224681 LOC102234277 LOC102234277 LOC102218889 LOC102218889 sae1 sae1 senp6 senp6 LOC102230500 LOC102230500 LOC102223095 LOC102223095 LOC102218172 LOC102218172 LOC102235471 LOC102235471 top2a top2a LOC102217601 LOC102217601 sumo2 sumo2 kctd2 kctd2 zmiz1 zmiz1 LOC102218184 LOC102218184 uba2 uba2 top2b top2b ube2i ube2i LOC102237688 LOC102237688 aqp11 aqp11 kctd9 kctd9 zmiz2 zmiz2 pias4 pias4 LOC102221529 LOC102221529 ENSXMAP00000036223 ENSXMAP00000036223 LOC102225145 LOC102225145 sumo1 sumo1 LOC102234345 LOC102234345
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102224681UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC102234277SUMO specific peptidase 5. (260 aa)
LOC102218889Protein inhibitor of activated STAT, 1b. (656 aa)
sae1SUMO1 activating enzyme subunit 1. (345 aa)
senp6ULP_PROTEASE domain-containing protein. (1053 aa)
LOC102230500Zinc finger MIZ-type containing 2. (925 aa)
LOC102223095DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (503 aa)
LOC102218172Small ubiquitin-related modifier. (96 aa)
LOC102235471SUMO specific peptidase 2. (598 aa)
top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1536 aa)
LOC102217601Si:dkey-21c19.3. (729 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
kctd2Potassium channel tetramerization domain containing 2. (209 aa)
zmiz1Zinc finger MIZ-type containing 1. (1068 aa)
LOC102218184Ubiquitin-like domain-containing protein. (147 aa)
uba2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (650 aa)
top2bDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1589 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC102237688SP-RING-type domain-containing protein. (1111 aa)
aqp11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
kctd9Potassium channel tetramerization domain containing 9a. (389 aa)
zmiz2SP-RING-type domain-containing protein. (885 aa)
pias4Protein inhibitor of activated STAT, 4a. (507 aa)
LOC102221529Uncharacterized protein. (559 aa)
ENSXMAP00000036223Rad60-SLD domain-containing protein. (107 aa)
LOC102225145SUMO specific peptidase 7. (1032 aa)
sumo1Small ubiquitin like modifier 1. (150 aa)
LOC102234345Small ubiquitin-related modifier. (94 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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