STRINGSTRING
rad51 rad51 LOC102224037 LOC102224037 mre11 mre11 rbbp8 rbbp8 nbn nbn atr atr brca1 brca1 exo1 exo1 recql4 recql4 atm atm tp53bp1 tp53bp1 ankrd11 ankrd11 dna2 dna2 rad52 rad52 rad50 rad50
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
LOC102224037Checkpoint kinase 2. (442 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (743 aa)
rbbp8Uncharacterized protein. (638 aa)
nbnNibrin. (831 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2443 aa)
brca1Uncharacterized protein. (1370 aa)
exo1Exonuclease 1. (777 aa)
recql4RecQ helicase-like 4. (1385 aa)
atmATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2875 aa)
tp53bp1Tumor protein p53 binding protein, 1. (1252 aa)
ankrd11Ankyrin repeat domain 11. (2826 aa)
dna2Uncharacterized protein. (1324 aa)
rad52RAD52 homolog, DNA repair protein. (445 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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