(12 nodes) Mismatch repair complex network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pms1	PMS1 homolog 1, mismatch repair system component. (860 aa)
	msh5	MutS homolog 5. (787 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (937 aa)
	pms2	PMS1 homolog 2, mismatch repair system component. (826 aa)
	ENSXMAP00000025311	DNA_MISMATCH_REPAIR_2 domain-containing protein. (351 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (754 aa)
	msh4	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (912 aa)
	mlh3	MutL homolog 3 (E. coli). (1151 aa)
	ENSXMAP00000034387	DNA_MISMATCH_REPAIR_2 domain-containing protein. (228 aa)
	ENSXMAP00000034984	MutS_I domain-containing protein. (206 aa)
	MSH3	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1112 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1376 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000025311	ENSXMAP00000034984	ENSXMAP00000025311	ENSXMAP00000034984	DNA_MISMATCH_REPAIR_2 domain-containing protein.	MutS_I domain-containing protein.	0.872
ENSXMAP00000025311	MSH3	ENSXMAP00000025311	ENSXMAP00000038619	DNA_MISMATCH_REPAIR_2 domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.887
ENSXMAP00000025311	mlh1	ENSXMAP00000025311	ENSXMAP00000027751	DNA_MISMATCH_REPAIR_2 domain-containing protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.983
ENSXMAP00000025311	mlh3	ENSXMAP00000025311	ENSXMAP00000032233	DNA_MISMATCH_REPAIR_2 domain-containing protein.	MutL homolog 3 (E. coli).	0.915
ENSXMAP00000025311	msh4	ENSXMAP00000025311	ENSXMAP00000031743	DNA_MISMATCH_REPAIR_2 domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.679
ENSXMAP00000025311	msh6	ENSXMAP00000025311	ENSXMAP00000041235	DNA_MISMATCH_REPAIR_2 domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.981
ENSXMAP00000025311	pms1	ENSXMAP00000025311	ENSXMAP00000005916	DNA_MISMATCH_REPAIR_2 domain-containing protein.	PMS1 homolog 1, mismatch repair system component.	0.964
ENSXMAP00000025311	pms2	ENSXMAP00000025311	ENSXMAP00000014926	DNA_MISMATCH_REPAIR_2 domain-containing protein.	PMS1 homolog 2, mismatch repair system component.	0.974
ENSXMAP00000034387	ENSXMAP00000034984	ENSXMAP00000034387	ENSXMAP00000034984	DNA_MISMATCH_REPAIR_2 domain-containing protein.	MutS_I domain-containing protein.	0.872
ENSXMAP00000034387	MSH3	ENSXMAP00000034387	ENSXMAP00000038619	DNA_MISMATCH_REPAIR_2 domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.887
ENSXMAP00000034387	mlh1	ENSXMAP00000034387	ENSXMAP00000027751	DNA_MISMATCH_REPAIR_2 domain-containing protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.983
ENSXMAP00000034387	mlh3	ENSXMAP00000034387	ENSXMAP00000032233	DNA_MISMATCH_REPAIR_2 domain-containing protein.	MutL homolog 3 (E. coli).	0.915
ENSXMAP00000034387	msh4	ENSXMAP00000034387	ENSXMAP00000031743	DNA_MISMATCH_REPAIR_2 domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.682
ENSXMAP00000034387	msh6	ENSXMAP00000034387	ENSXMAP00000041235	DNA_MISMATCH_REPAIR_2 domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.981
ENSXMAP00000034387	pms1	ENSXMAP00000034387	ENSXMAP00000005916	DNA_MISMATCH_REPAIR_2 domain-containing protein.	PMS1 homolog 1, mismatch repair system component.	0.964
ENSXMAP00000034387	pms2	ENSXMAP00000034387	ENSXMAP00000014926	DNA_MISMATCH_REPAIR_2 domain-containing protein.	PMS1 homolog 2, mismatch repair system component.	0.974
ENSXMAP00000034984	ENSXMAP00000025311	ENSXMAP00000034984	ENSXMAP00000025311	MutS_I domain-containing protein.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.872
ENSXMAP00000034984	ENSXMAP00000034387	ENSXMAP00000034984	ENSXMAP00000034387	MutS_I domain-containing protein.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.872
ENSXMAP00000034984	mlh1	ENSXMAP00000034984	ENSXMAP00000027751	MutS_I domain-containing protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.918
ENSXMAP00000034984	mlh3	ENSXMAP00000034984	ENSXMAP00000032233	MutS_I domain-containing protein.	MutL homolog 3 (E. coli).	0.898