(8 nodes) Delta DNA polymerase complex, and XPG-I domain network (Xiphophorus maculatus)

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Your Input:
	LOC102220076	Zgc:110269. (347 aa)
	lig1	DNA ligase. (595 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa)
	fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	pold1	DNA polymerase. (1105 aa)
	pold4	Si:dkey-28b4.7. (108 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (528 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102220076	fen1	ENSXMAP00000004359	ENSXMAP00000006136	Zgc:110269.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.905
LOC102220076	lig1	ENSXMAP00000004359	ENSXMAP00000005879	Zgc:110269.	DNA ligase.	0.970
LOC102220076	pcna	ENSXMAP00000004359	ENSXMAP00000014924	Zgc:110269.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.989
LOC102220076	pold1	ENSXMAP00000004359	ENSXMAP00000011793	Zgc:110269.	DNA polymerase.	0.980
LOC102220076	pold2	ENSXMAP00000004359	ENSXMAP00000015386	Zgc:110269.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.931
LOC102220076	pold3	ENSXMAP00000004359	ENSXMAP00000006066	Zgc:110269.	Polymerase (DNA-directed), delta 3, accessory subunit.	0.735
LOC102220076	pold4	ENSXMAP00000004359	ENSXMAP00000013796	Zgc:110269.	Si:dkey-28b4.7.	0.687
fen1	LOC102220076	ENSXMAP00000006136	ENSXMAP00000004359	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Zgc:110269.	0.905
fen1	lig1	ENSXMAP00000006136	ENSXMAP00000005879	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA ligase.	0.970
fen1	pcna	ENSXMAP00000006136	ENSXMAP00000014924	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.989
fen1	pold1	ENSXMAP00000006136	ENSXMAP00000011793	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA polymerase.	0.980
fen1	pold2	ENSXMAP00000006136	ENSXMAP00000015386	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Polymerase (DNA directed), delta 2, regulatory subunit.	0.931
fen1	pold3	ENSXMAP00000006136	ENSXMAP00000006066	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Polymerase (DNA-directed), delta 3, accessory subunit.	0.735
fen1	pold4	ENSXMAP00000006136	ENSXMAP00000013796	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Si:dkey-28b4.7.	0.687
lig1	LOC102220076	ENSXMAP00000005879	ENSXMAP00000004359	DNA ligase.	Zgc:110269.	0.970
lig1	fen1	ENSXMAP00000005879	ENSXMAP00000006136	DNA ligase.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.970
lig1	pcna	ENSXMAP00000005879	ENSXMAP00000014924	DNA ligase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.998
lig1	pold1	ENSXMAP00000005879	ENSXMAP00000011793	DNA ligase.	DNA polymerase.	0.971
lig1	pold2	ENSXMAP00000005879	ENSXMAP00000015386	DNA ligase.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.851
lig1	pold3	ENSXMAP00000005879	ENSXMAP00000006066	DNA ligase.	Polymerase (DNA-directed), delta 3, accessory subunit.	0.569