STRINGSTRING
mcm2 mcm2 MCMDC2 MCMDC2 gins2 gins2 timeless timeless cdc7 cdc7 mcm5 mcm5 orc5 orc5 dbf4 dbf4 orc3 orc3 mcm10 mcm10 wdhd1 wdhd1 orc4 orc4 cdc6 cdc6 cdc45 cdc45 gins3 gins3 mcm7 mcm7 CLSPN CLSPN mcm6 mcm6 gins1 gins1 pola1 pola1 gins4 gins4 ENSXMAP00000024871 ENSXMAP00000024871 mcm8 mcm8 Mcm9 Mcm9 tipin tipin orc2 orc2 mcm3 mcm3 cdt1 cdt1 orc1 orc1 mcm4 mcm4 LOC111609834 LOC111609834
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mcm2DNA helicase; Belongs to the MCM family. (886 aa)
MCMDC2Minichromosome maintenance domain containing 2. (649 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
timelessTimeless circadian clock. (1260 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (606 aa)
mcm5DNA helicase; Belongs to the MCM family. (695 aa)
orc5Origin recognition complex, subunit 5. (442 aa)
dbf4DBF4 zinc finger. (593 aa)
orc3Origin recognition complex, subunit 3. (722 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (870 aa)
wdhd1WD repeat and HMG-box DNA binding protein 1. (1102 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (579 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
gins3GINS complex subunit 3. (211 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (724 aa)
CLSPNClaspin. (1202 aa)
mcm6DNA helicase; Belongs to the MCM family. (816 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (189 aa)
pola1DNA polymerase. (1488 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa)
ENSXMAP00000024871MCM domain-containing protein; Belongs to the MCM family. (351 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (846 aa)
Mcm9Uncharacterized protein. (158 aa)
tipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (290 aa)
orc2Origin recognition complex, subunit 2. (594 aa)
mcm3DNA helicase; Belongs to the MCM family. (836 aa)
cdt1Chromatin licensing and DNA replication factor 1. (761 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (890 aa)
mcm4DNA helicase; Belongs to the MCM family. (868 aa)
LOC111609834DBF4-type domain-containing protein. (692 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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