67 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102225223	Uncharacterized protein. (948 aa)
	dcst1	DC-STAMP domain containing 1. (639 aa)
	LOC102237766	Poly [ADP-ribose] polymerase. (1776 aa)
	LOC102222153	Uncharacterized protein. (868 aa)
	c1qtnf4	C1q and TNF related 4. (424 aa)
	LOC102230552	Coiled-coil domain containing 3b. (289 aa)
	LOC102237370	Colony stimulating factor 1b (macrophage). (271 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (584 aa)
	ENSXMAP00000038106	Parkin RBR E3 ubiquitin protein ligase. (257 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (952 aa)
	LOC102229303	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
	tnfrsf1a	Tumor necrosis factor receptor superfamily, member 1a. (365 aa)
	sigirr	Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain. (518 aa)
	otud4	OTU domain-containing protein. (1243 aa)
	spata2	Spermatogenesis associated 2. (566 aa)
	LOC102220665	LSM14A mRNA processing body assembly factor a. (459 aa)
	sharpin	SHANK-associated RH domain interacting protein. (435 aa)
	LOC102218487-2	Uncharacterized protein. (422 aa)
	ENSXMAP00000032446	Ubiquitin-like domain-containing protein. (138 aa)
	ttll12	Tubulin tyrosine ligase-like family, member 12. (627 aa)
	ube2k	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
	LOC102228854	Interferon regulatory factor 3. (465 aa)
	pias4	Protein inhibitor of activated STAT, 4a. (507 aa)
	sh2b3	SH2B adaptor protein 3. (708 aa)
	trim44	Tripartite motif containing 44. (357 aa)
	LOC102221531	Poly [ADP-ribose] polymerase. (1801 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1745 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	ENSXMAP00000025020	Uncharacterized protein. (125 aa)
	ccdc3	Coiled-coil domain containing 3a. (297 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (584 aa)
	gas6	Uncharacterized protein. (650 aa)
	il1r2	Interleukin 1 receptor type 2. (420 aa)
	ythdf2	YTH N(6)-methyladenosine RNA binding protein 2. (638 aa)
	LOC102237454	RAB guanine nucleotide exchange factor (GEF) 1, like. (510 aa)
	lsm14a	LSM14A mRNA processing body assembly factor b. (441 aa)
	edn1	Endothelin 1. (197 aa)
	rnf185	Ring finger protein 185. (200 aa)
	M4AE11_XIPMA	Nuclear receptor subfamily 1, group H, member 5. (494 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	adar	Adenosine deaminase RNA specific. (1359 aa)
	LOC106699956	Uncharacterized protein. (383 aa)
	adam17	ADAM metallopeptidase domain 17b. (841 aa)
	ythdf3	YTH N(6)-methyladenosine RNA binding protein 3. (603 aa)
	LOC102231502	Cylindromatosis (turban tumor syndrome), b. (712 aa)
	rnf113a	Ring finger protein 113A. (322 aa)
	il6st	Uncharacterized protein. (885 aa)
	samhd1	SAM domain and HD domain 1. (627 aa)
	LOC102218487	HD domain-containing protein. (473 aa)
	LOC102217501	Poly [ADP-ribose] polymerase. (1803 aa)
	ecm1	Uncharacterized protein. (473 aa)
	rabgef1	RAB guanine nucleotide exchange factor (GEF) 1. (474 aa)
	LOC102233658	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family. (766 aa)
	trim32	Tripartite motif containing 32. (622 aa)
	supt5h	Transcription elongation factor SPT5. (1062 aa)
	LOC102228722	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (735 aa)
	irak1	Interleukin-1 receptor-associated kinase 1. (652 aa)
	LOC102232663	Uncharacterized protein. (429 aa)
	tbk1	TANK-binding kinase 1. (721 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1325 aa)
	traip	TRAF-interacting protein. (448 aa)
	OTOP1	Otopetrin 1. (582 aa)
	otulin	OTU deubiquitinase with linear linkage specificity a. (682 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	fadd	Uncharacterized protein. (196 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000032446	LOC102229303	ENSXMAP00000032446	ENSXMAP00000037698	Ubiquitin-like domain-containing protein.	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.503
ENSXMAP00000032446	mul1	ENSXMAP00000032446	ENSXMAP00000012442	Ubiquitin-like domain-containing protein.	Mitochondrial E3 ubiquitin protein ligase 1b.	0.697
ENSXMAP00000032446	ripk2	ENSXMAP00000032446	ENSXMAP00000038180	Ubiquitin-like domain-containing protein.	Receptor-interacting serine-threonine kinase 2.	0.412
ENSXMAP00000032446	ube2k	ENSXMAP00000032446	ENSXMAP00000030453	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.503
ENSXMAP00000038106	LOC102229303	ENSXMAP00000038106	ENSXMAP00000037698	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.503
ENSXMAP00000038106	ripk2	ENSXMAP00000038106	ENSXMAP00000038180	Parkin RBR E3 ubiquitin protein ligase.	Receptor-interacting serine-threonine kinase 2.	0.412
ENSXMAP00000038106	ube2k	ENSXMAP00000038106	ENSXMAP00000030453	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.503
LOC102222153	adam17	ENSXMAP00000040823	ENSXMAP00000009871	Uncharacterized protein.	ADAM metallopeptidase domain 17b.	0.902
LOC102225223	LOC102228722	ENSXMAP00000001310	ENSXMAP00000003791	Uncharacterized protein.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.957
LOC102225223	fadd	ENSXMAP00000001310	ENSXMAP00000000793	Uncharacterized protein.	Uncharacterized protein.	0.598
LOC102225223	ripk2	ENSXMAP00000001310	ENSXMAP00000038180	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 2.	0.492
LOC102225223	sharpin	ENSXMAP00000001310	ENSXMAP00000033742	Uncharacterized protein.	SHANK-associated RH domain interacting protein.	0.601
LOC102225223	spata2	ENSXMAP00000001310	ENSXMAP00000035829	Uncharacterized protein.	Spermatogenesis associated 2.	0.950
LOC102225223	tbk1	ENSXMAP00000001310	ENSXMAP00000002779	Uncharacterized protein.	TANK-binding kinase 1.	0.596
LOC102225223	tnfrsf1a	ENSXMAP00000001310	ENSXMAP00000037629	Uncharacterized protein.	Tumor necrosis factor receptor superfamily, member 1a.	0.895
LOC102225266	cav3	ENSXMAP00000001534	ENSXMAP00000038231	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.593
LOC102228722	LOC102225223	ENSXMAP00000003791	ENSXMAP00000001310	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Uncharacterized protein.	0.957
LOC102228722	LOC102228854	ENSXMAP00000003791	ENSXMAP00000030119	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Interferon regulatory factor 3.	0.990
LOC102228722	LOC102231502	ENSXMAP00000003791	ENSXMAP00000009654	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Cylindromatosis (turban tumor syndrome), b.	0.958
LOC102228722	LOC102233658	ENSXMAP00000003791	ENSXMAP00000006433	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family.	0.958