40 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102238093	GTP_cyclohydroI domain-containing protein. (164 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC102221555	Adrenoceptor alpha 1Ab. (467 aa)
	LOC102222598	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (469 aa)
	adra1d	Adrenoceptor alpha 1D. (514 aa)
	LOC102234633	Uncharacterized protein. (169 aa)
	LOC102232317	G_PROTEIN_RECEP_F1_2 domain-containing protein. (490 aa)
	kcne4	Potassium voltage-gated channel, Isk-related family, member 4. (228 aa)
	sri	Uncharacterized protein. (260 aa)
	LOC102217901	Adrenoceptor alpha 1Bb. (585 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (444 aa)
	gch1	GTP cyclohydrolase 1. (255 aa)
	LOC102230071	Uncharacterized protein. (282 aa)
	scn4b	Sodium channel, voltage-gated, type IV, beta a. (233 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (691 aa)
	LOC102223594	Nitric oxide synthase 1 (neuronal) adaptor protein b. (517 aa)
	LOC102234293	Grancalcin. (237 aa)
	rnls	Renalase, FAD-dependent amine oxidase. (349 aa)
	LOC111609824	GTP cyclohydrolase 2. (236 aa)
	edn1	Endothelin 1. (197 aa)
	LOC102230049	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (420 aa)
	tmem161b	Transmembrane protein 161B. (492 aa)
	nos1ap	PID domain-containing protein. (753 aa)
	LOC102224234	Sodium channel, voltage-gated, type I, beta a. (216 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	scn3b	Sodium channel, voltage-gated, type III, beta. (219 aa)
	adm	Uncharacterized protein. (207 aa)
	LOC102227674	Si:dkey-34e4.1. (663 aa)
	LOC102219201	Uncharacterized protein; Belongs to the potassium channel family. (742 aa)
	LOC102216442	Sodium channel, voltage-gated, type I, beta b. (223 aa)
	LOC102226870	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (417 aa)
	scn2b	Sodium channel, voltage-gated, type II, beta. (219 aa)
	ENSXMAP00000034786	Uncharacterized protein. (134 aa)
	LOC102221221	Adrenoceptor alpha 1Aa. (480 aa)
	ENSXMAP00000036377	Endothelin 2. (163 aa)
	ENSXMAP00000036757	Uncharacterized protein. (165 aa)
	pln	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (53 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC102226016	Junction plakoglobin a. (721 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDNRA	ENSXMAP00000036377	ENSXMAP00000027944	ENSXMAP00000036377	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 2.	0.598
EDNRA	LOC102222598	ENSXMAP00000027944	ENSXMAP00000004532	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.575
EDNRA	LOC102226870	ENSXMAP00000027944	ENSXMAP00000032282	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.573
EDNRA	LOC102230049	ENSXMAP00000027944	ENSXMAP00000017600	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.571
EDNRA	edn1	ENSXMAP00000027944	ENSXMAP00000016173	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.996
EDNRA	ednra	ENSXMAP00000027944	ENSXMAP00000009624	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.903
ENSXMAP00000034786	LOC102219201	ENSXMAP00000034786	ENSXMAP00000030623	Uncharacterized protein.	Uncharacterized protein; Belongs to the potassium channel family.	0.979
ENSXMAP00000034786	LOC102223594	ENSXMAP00000034786	ENSXMAP00000012640	Uncharacterized protein.	Nitric oxide synthase 1 (neuronal) adaptor protein b.	0.414
ENSXMAP00000034786	LOC102227674	ENSXMAP00000034786	ENSXMAP00000030269	Uncharacterized protein.	Si:dkey-34e4.1.	0.414
ENSXMAP00000034786	kcne4	ENSXMAP00000034786	ENSXMAP00000008285	Uncharacterized protein.	Potassium voltage-gated channel, Isk-related family, member 4.	0.479
ENSXMAP00000034786	kcnq1	ENSXMAP00000034786	ENSXMAP00000011784	Uncharacterized protein.	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	0.979
ENSXMAP00000034786	nos1ap	ENSXMAP00000034786	ENSXMAP00000023037	Uncharacterized protein.	PID domain-containing protein.	0.414
ENSXMAP00000034786	scn4b	ENSXMAP00000034786	ENSXMAP00000010761	Uncharacterized protein.	Sodium channel, voltage-gated, type IV, beta a.	0.400
ENSXMAP00000036377	EDNRA	ENSXMAP00000036377	ENSXMAP00000027944	Endothelin 2.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.598
ENSXMAP00000036377	LOC102222598	ENSXMAP00000036377	ENSXMAP00000004532	Endothelin 2.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.521
ENSXMAP00000036377	LOC102226870	ENSXMAP00000036377	ENSXMAP00000032282	Endothelin 2.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.521
ENSXMAP00000036377	LOC102230049	ENSXMAP00000036377	ENSXMAP00000017600	Endothelin 2.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.521
ENSXMAP00000036377	edn1	ENSXMAP00000036377	ENSXMAP00000016173	Endothelin 2.	Endothelin 1.	0.610
ENSXMAP00000036377	ednra	ENSXMAP00000036377	ENSXMAP00000009624	Endothelin 2.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.598
ENSXMAP00000036757	LOC102234633	ENSXMAP00000036757	ENSXMAP00000005142	Uncharacterized protein.	Uncharacterized protein.	0.744