30 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (539 aa)
	dhrs3	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (748 aa)
	SMAD4	Mothers against decapentaplegic homolog. (512 aa)
	LOC102221328	T-box transcription factor 3b. (498 aa)
	LOC102231514	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (598 aa)
	LOC102226276	Neuropeptide Y receptor Y2, like; Belongs to the G-protein coupled receptor 1 family. (405 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	LOC102229158	Uncharacterized protein. (341 aa)
	zfpm2	Zinc finger protein, FOG family member 2a. (1171 aa)
	ENSXMAP00000023172	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (288 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC102225323	Mothers against decapentaplegic homolog. (563 aa)
	LOC102233559	Neuropeptide Y receptor Y7; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	LOC102217453	Neuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	LOC102231522	Uncharacterized protein. (452 aa)
	edn1	Endothelin 1. (197 aa)
	LOC102237203	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (506 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (988 aa)
	LOC102230588	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1144 aa)
	nkx2-5	NK2 homeobox 5. (319 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (444 aa)
	LOC102225576	Prolactin releasing hormone receptor 2a. (365 aa)
	tbx3	T-box transcription factor 3a. (708 aa)
	LOC102228719	Mothers against decapentaplegic homolog. (503 aa)
	ILK	Integrin linked kinase. (452 aa)
	LOC102216648	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
	LOC102226271	JunE proto-oncogene, AP-1 transcription factor subunit. (324 aa)
	LOC102235215	Neuropilin 2b. (1026 aa)
	LOC102225057	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (403 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDNRA	edn1	ENSXMAP00000027944	ENSXMAP00000016173	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.996
EDNRA	ednra	ENSXMAP00000027944	ENSXMAP00000009624	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.903
ILK	LOC102231522	ENSXMAP00000005043	ENSXMAP00000017808	Integrin linked kinase.	Uncharacterized protein.	0.900
LOC102216648	nkx2-5	ENSXMAP00000004086	ENSXMAP00000010285	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	NK2 homeobox 5.	0.412
LOC102221328	nkx2-5	ENSXMAP00000031046	ENSXMAP00000010285	T-box transcription factor 3b.	NK2 homeobox 5.	0.461
LOC102225057	nkx2-5	ENSXMAP00000000961	ENSXMAP00000010285	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	NK2 homeobox 5.	0.412
LOC102225323	LOC102230588	ENSXMAP00000021000	ENSXMAP00000013728	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.651
LOC102225323	LOC102231514	ENSXMAP00000021000	ENSXMAP00000029495	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.626
LOC102225323	TGFBR2	ENSXMAP00000021000	ENSXMAP00000014396	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.626
LOC102225323	bmpr2	ENSXMAP00000021000	ENSXMAP00000013762	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.651
LOC102228719	LOC102230588	ENSXMAP00000005074	ENSXMAP00000013728	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.651
LOC102228719	LOC102231514	ENSXMAP00000005074	ENSXMAP00000029495	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.626
LOC102228719	SMAD4	ENSXMAP00000005074	ENSXMAP00000031130	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.900
LOC102228719	TGFBR2	ENSXMAP00000005074	ENSXMAP00000014396	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.626
LOC102228719	bmpr2	ENSXMAP00000005074	ENSXMAP00000013762	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.651
LOC102230588	LOC102225323	ENSXMAP00000013728	ENSXMAP00000021000	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.651
LOC102230588	LOC102228719	ENSXMAP00000013728	ENSXMAP00000005074	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.651
LOC102230588	SMAD4	ENSXMAP00000013728	ENSXMAP00000031130	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.651
LOC102231514	LOC102225323	ENSXMAP00000029495	ENSXMAP00000021000	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.626
LOC102231514	LOC102228719	ENSXMAP00000029495	ENSXMAP00000005074	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.626