(62 nodes) Carbon-carbon lyase activity network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102221516	tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). (745 aa)
	LOC102231048	Malic enzyme. (622 aa)
	clybl	Citrate lyase beta like. (354 aa)
	hdc	Histidine decarboxylase. (670 aa)
	ppcdc	Phosphopantothenoylcysteine decarboxylase. (208 aa)
	LOC102223792	Antizyme inhibitor 1b; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (435 aa)
	LOC102235676	CD99 molecule. (213 aa)
	ddc	Dopa decarboxylase. (480 aa)
	LOC102221767	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (522 aa)
	hmgcl	3-hydroxy-3-methylglutaryl-CoA lyase. (337 aa)
	fahd1	Fumarylacetoacetate hydrolase domain containing 1. (221 aa)
	pisd	Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (466 aa)
	me2	Malic enzyme. (582 aa)
	sgpl1	Sphingosine-1-phosphate lyase 1. (565 aa)
	LOC102219194	Immunoresponsive gene 1, like. (494 aa)
	acmsd	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (373 aa)
	uxs1	UDP-glucuronate decarboxylase 1. (441 aa)
	ECHDC1	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (312 aa)
	gad1	Glutamate decarboxylase 1a. (595 aa)
	got1	Aspartate aminotransferase. (410 aa)
	odc1	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (460 aa)
	LOC102223115	Photolyase/cryptochrome alpha/beta domain-containing protein. (625 aa)
	LOC102236450	AIRC domain-containing protein. (1012 aa)
	LOC102225933	Threonine aldolase 1. (418 aa)
	hacl1	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (572 aa)
	LOC102225230	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	npl	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); Belongs to the DapA family. (305 aa)
	urad	Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase. (174 aa)
	LOC102236105	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	cd99l2	CD99 molecule-like 2. (229 aa)
	LOC102233507	Glutamate decarboxylase 1b. (653 aa)
	urod	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (368 aa)
	acod1	Aconitate decarboxylase 1. (433 aa)
	LOC102236270	Malate synthase-like. (549 aa)
	LOC102227534	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	pck1	Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
	mlycd	Malonyl-CoA decarboxylase. (504 aa)
	M4A4N3_XIPMA	Immunoresponsive gene 1, like. (509 aa)
	LOC102234506	Cryptochrome DASH. (521 aa)
	LOC102232942	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	gad2	Glutamate decarboxylase 2. (585 aa)
	me1	Malic enzyme. (588 aa)
	pck2	Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (635 aa)
	LOC102238057	Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (514 aa)
	GOT1	Aspartate aminotransferase. (410 aa)
	hoga1	4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (323 aa)
	amd1	S-adenosylmethionine decarboxylase proenzyme. (335 aa)
	dera	Deoxyribose-phosphate aldolase (putative). (417 aa)
	LOC102226393	Zgc:66475. (506 aa)
	armt1	Acidic residue methyltransferase 1. (450 aa)
	ggcx	Gamma-glutamyl carboxylase. (764 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
	M3ZKJ8_XIPMA	Uncharacterized protein. (508 aa)
	LOC102231251	Glutamate decarboxylase like 1. (502 aa)
	azin1	Antizyme inhibitor 1a; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (451 aa)
	umps	Uridine monophosphate synthetase. (487 aa)
	LOC102219615	Cryptochrome circadian regulator 1b. (574 aa)
	LOC102238419	Tantalus domain-containing protein. (1143 aa)
	pdxdc1	Pyridoxal-dependent decarboxylase domain containing 1. (792 aa)
	mocs1	Molybdenum cofactor synthesis 1. (397 aa)
	hmgcll1	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (337 aa)
	csad	Cysteine sulfinic acid decarboxylase. (494 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ECHDC1	LOC102236270	ENSXMAP00000028349	ENSXMAP00000010958	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Malate synthase-like.	0.840
ECHDC1	hmgcl	ENSXMAP00000028349	ENSXMAP00000019089	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.579
ECHDC1	hmgcll1	ENSXMAP00000028349	ENSXMAP00000033812	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.	0.579
GOT1	LOC102223792	ENSXMAP00000005691	ENSXMAP00000028014	Aspartate aminotransferase.	Antizyme inhibitor 1b; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.610
GOT1	LOC102231048	ENSXMAP00000005691	ENSXMAP00000039721	Aspartate aminotransferase.	Malic enzyme.	0.455
GOT1	LOC102231251	ENSXMAP00000005691	ENSXMAP00000002697	Aspartate aminotransferase.	Glutamate decarboxylase like 1.	0.825
GOT1	LOC102233507	ENSXMAP00000005691	ENSXMAP00000011531	Aspartate aminotransferase.	Glutamate decarboxylase 1b.	0.825
GOT1	LOC102236270	ENSXMAP00000005691	ENSXMAP00000010958	Aspartate aminotransferase.	Malate synthase-like.	0.593
GOT1	azin1	ENSXMAP00000005691	ENSXMAP00000002415	Aspartate aminotransferase.	Antizyme inhibitor 1a; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.610
GOT1	csad	ENSXMAP00000005691	ENSXMAP00000038601	Aspartate aminotransferase.	Cysteine sulfinic acid decarboxylase.	0.825
GOT1	ddc	ENSXMAP00000005691	ENSXMAP00000000779	Aspartate aminotransferase.	Dopa decarboxylase.	0.917
GOT1	fahd1	ENSXMAP00000005691	ENSXMAP00000019897	Aspartate aminotransferase.	Fumarylacetoacetate hydrolase domain containing 1.	0.401
GOT1	gad1	ENSXMAP00000005691	ENSXMAP00000028515	Aspartate aminotransferase.	Glutamate decarboxylase 1a.	0.825
GOT1	gad2	ENSXMAP00000005691	ENSXMAP00000008331	Aspartate aminotransferase.	Glutamate decarboxylase 2.	0.825
GOT1	got1	ENSXMAP00000005691	ENSXMAP00000028778	Aspartate aminotransferase.	Aspartate aminotransferase.	0.901
GOT1	hoga1	ENSXMAP00000005691	ENSXMAP00000005668	Aspartate aminotransferase.	4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.	0.909
GOT1	me1	ENSXMAP00000005691	ENSXMAP00000006909	Aspartate aminotransferase.	Malic enzyme.	0.455
GOT1	me2	ENSXMAP00000005691	ENSXMAP00000021847	Aspartate aminotransferase.	Malic enzyme.	0.455
GOT1	odc1	ENSXMAP00000005691	ENSXMAP00000018535	Aspartate aminotransferase.	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.610
GOT1	pck1	ENSXMAP00000005691	ENSXMAP00000010473	Aspartate aminotransferase.	Phosphoenolpyruvate carboxykinase 1 (soluble).	0.831