(72 nodes) Viral life cycle network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ddb1	Damage-specific DNA binding protein 1. (1081 aa)
	atg16l1	ATG16 autophagy related 16-like 1 (S. cerevisiae). (603 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	pdcd6ip	Programmed cell death 6 interacting protein. (765 aa)
	LOC102221567	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	LOC102236184	Zgc:171927. (214 aa)
	LOC102223583	Solute carrier family 3 member 2b. (566 aa)
	LOC102231865	Uncharacterized protein. (203 aa)
	LOC102225663	Si:ch211-288d18.1. (535 aa)
	tbc1d20	TBC1 domain family, member 20. (397 aa)
	LOC102237143	Two pore segment channel 3. (784 aa)
	siva1	SIVA1, apoptosis-inducing factor. (168 aa)
	LOC102232058	Ig-like domain-containing protein. (237 aa)
	tpcn1	Two pore segment channel 1. (832 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (925 aa)
	phb	Prohibitin. (271 aa)
	slc3a2	Uncharacterized protein. (492 aa)
	LOC111608121	Si:dkey-33i11.1. (643 aa)
	LOC111608122	Uncharacterized protein. (433 aa)
	LOC102236031	Multivesicular body subunit 12Bb. (244 aa)
	LOC102227389	Uncharacterized protein; Belongs to the AAA ATPase family. (435 aa)
	LOC106699654	Uncharacterized protein. (599 aa)
	jpt2	Jupiter microtubule associated homolog 2. (232 aa)
	mvb12a	Uncharacterized protein. (281 aa)
	M4AIP1_XIPMA	ATG16 autophagy related 16-like 2 (S. cerevisiae). (283 aa)
	tsg101	Tumor susceptibility 101a. (390 aa)
	LOC102235305	Peptidase S72 domain-containing protein. (908 aa)
	LOC102218920	Uncharacterized protein. (202 aa)
	LOC102221267	Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (171 aa)
	LOC102232293	Apolipoprotein Ea. (251 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (437 aa)
	lrsam1	Leucine rich repeat and sterile alpha motif containing 1. (732 aa)
	LOC102235681	USP6 N-terminal like. (696 aa)
	ist1	IST1 factor associated with ESCRT-III. (348 aa)
	LOC102216911	Apolipoprotein Eb. (265 aa)
	gas6	Uncharacterized protein. (650 aa)
	LOC102228541	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	agtr1	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	LOC111608551	Uncharacterized protein. (618 aa)
	ENSXMAP00000020770	Si:dkey-185p13.1. (95 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (326 aa)
	mvb12b	Multivesicular body subunit 12Ba. (293 aa)
	LOC102221597	Si:dkeyp-19e1.3. (829 aa)
	Pikfyve	PIPK domain-containing protein. (320 aa)
	ENSXMAP00000024152	Uncharacterized protein. (448 aa)
	cxadr	CXADR Ig-like cell adhesion molecule. (382 aa)
	ENSXMAP00000025221	Uncharacterized protein. (431 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	vps37b	Zgc:114173. (284 aa)
	vta1	Vesicle (multivesicular body) trafficking 1. (320 aa)
	ENSXMAP00000026401	Uncharacterized protein. (384 aa)
	pc	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
	tpcn2	Uncharacterized protein. (721 aa)
	LOC102236176	Uncharacterized protein. (752 aa)
	LOC106700207	Si:dkey-202g17.3. (483 aa)
	ENSXMAP00000032574	Uncharacterized protein. (311 aa)
	uvrag	UV radiation resistance associated gene. (730 aa)
	ENSXMAP00000033102	Uncharacterized protein. (435 aa)
	ENSXMAP00000033961	Uncharacterized protein. (153 aa)
	LOC102226374	Tripartite motif containing 62, tandem duplicate 1. (475 aa)
	ENSXMAP00000035483	Uncharacterized protein. (480 aa)
	LOC111608534	Uncharacterized protein. (817 aa)
	dag1	Dystroglycan 1. (893 aa)
	LOC102236931	ZRAB1B, member RAS oncogene family a. (201 aa)
	LOC102229676	Vesicle-associated membrane protein 8 (endobrevin). (122 aa)
	LOC102221191	Nectin cell adhesion molecule 4b. (583 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (631 aa)
	ENSXMAP00000039056	V-SNARE coiled-coil homology domain-containing protein. (103 aa)
	LOC102233214	Zgc:63863. (445 aa)
	vps4a	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (475 aa)
	ENSXMAP00000040979	Uncharacterized protein. (381 aa)
	nectin1	Nectin cell adhesion molecule 1b. (508 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000020770	ist1	ENSXMAP00000020770	ENSXMAP00000018353	Si:dkey-185p13.1.	IST1 factor associated with ESCRT-III.	0.915
ENSXMAP00000020770	pdcd6ip	ENSXMAP00000020770	ENSXMAP00000003027	Si:dkey-185p13.1.	Programmed cell death 6 interacting protein.	0.727
ENSXMAP00000020770	tsg101	ENSXMAP00000020770	ENSXMAP00000015189	Si:dkey-185p13.1.	Tumor susceptibility 101a.	0.512
ENSXMAP00000020770	vta1	ENSXMAP00000020770	ENSXMAP00000026369	Si:dkey-185p13.1.	Vesicle (multivesicular body) trafficking 1.	0.938
ENSXMAP00000033961	Pikfyve	ENSXMAP00000033961	ENSXMAP00000023388	Uncharacterized protein.	PIPK domain-containing protein.	0.809
ENSXMAP00000039056	LOC102229676	ENSXMAP00000039056	ENSXMAP00000038479	V-SNARE coiled-coil homology domain-containing protein.	Vesicle-associated membrane protein 8 (endobrevin).	0.902
LOC102216911	LOC102221567	ENSXMAP00000018640	ENSXMAP00000004451	Apolipoprotein Eb.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.493
LOC102216911	cav1	ENSXMAP00000018640	ENSXMAP00000025385	Apolipoprotein Eb.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.414
LOC102218920	LOC102231865	ENSXMAP00000015808	ENSXMAP00000005770	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC102218920	LOC102233214	ENSXMAP00000015808	ENSXMAP00000039765	Uncharacterized protein.	Zgc:63863.	0.767
LOC102218920	LOC102236184	ENSXMAP00000015808	ENSXMAP00000004695	Uncharacterized protein.	Zgc:171927.	0.901
LOC102218920	M4AIP1_XIPMA	ENSXMAP00000015808	ENSXMAP00000014335	Uncharacterized protein.	ATG16 autophagy related 16-like 2 (S. cerevisiae).	0.404
LOC102218920	atg16l1	ENSXMAP00000015808	ENSXMAP00000000839	Uncharacterized protein.	ATG16 autophagy related 16-like 1 (S. cerevisiae).	0.404
LOC102218920	tbc1d20	ENSXMAP00000015808	ENSXMAP00000005898	Uncharacterized protein.	TBC1 domain family, member 20.	0.767
LOC102221191	LOC106699654	ENSXMAP00000038610	ENSXMAP00000011598	Nectin cell adhesion molecule 4b.	Uncharacterized protein.	0.693
LOC102221191	nectin1	ENSXMAP00000038610	ENSXMAP00000041577	Nectin cell adhesion molecule 4b.	Nectin cell adhesion molecule 1b.	0.867
LOC102221267	agtr1	ENSXMAP00000016040	ENSXMAP00000020202	Arginine vasopressin; Belongs to the vasopressin/oxytocin family.	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.	0.515
LOC102221567	LOC102216911	ENSXMAP00000004451	ENSXMAP00000018640	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Apolipoprotein Eb.	0.493
LOC102221567	LOC102228541	ENSXMAP00000004451	ENSXMAP00000019504	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.729
LOC102223583	slc3a2	ENSXMAP00000004819	ENSXMAP00000008648	Solute carrier family 3 member 2b.	Uncharacterized protein.	0.903