(19 nodes) Translesion synthesis network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (528 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	LOC102234371	Zgc:136908; Belongs to the AAA ATPase family. (810 aa)
	polk	Polymerase (DNA directed) kappa. (935 aa)
	rev1	REV1 DNA directed polymerase. (1363 aa)
	pold1	DNA polymerase. (1105 aa)
	rev3l	REV3 like, DNA directed polymerase zeta catalytic subunit. (3006 aa)
	pclaf	PCNA clamp associated factor. (117 aa)
	ENSXMAP00000024309	Poly [ADP-ribose] polymerase. (651 aa)
	poli	Polymerase (DNA directed) iota. (708 aa)
	sprtn	SprT-like N-terminal domain. (534 aa)
	LOC106699909	Zinc finger and BTB domain containing 1. (703 aa)
	dtl	Denticleless E3 ubiquitin protein ligase homolog (Drosophila). (649 aa)
	polh	Polymerase (DNA directed), eta. (720 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
	primpol	Primase and polymerase (DNA-directed). (525 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102234371	pcna	ENSXMAP00000012347	ENSXMAP00000014924	Zgc:136908; Belongs to the AAA ATPase family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.654
LOC102234371	polh	ENSXMAP00000012347	ENSXMAP00000010617	Zgc:136908; Belongs to the AAA ATPase family.	Polymerase (DNA directed), eta.	0.582
LOC102234371	poli	ENSXMAP00000012347	ENSXMAP00000024273	Zgc:136908; Belongs to the AAA ATPase family.	Polymerase (DNA directed) iota.	0.488
LOC102234371	sprtn	ENSXMAP00000012347	ENSXMAP00000033136	Zgc:136908; Belongs to the AAA ATPase family.	SprT-like N-terminal domain.	0.852
LOC102234371	vcp	ENSXMAP00000012347	ENSXMAP00000007519	Zgc:136908; Belongs to the AAA ATPase family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.900
dtl	pclaf	ENSXMAP00000017536	ENSXMAP00000032017	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	PCNA clamp associated factor.	0.599
dtl	pcna	ENSXMAP00000017536	ENSXMAP00000014924	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.972
dtl	pold1	ENSXMAP00000017536	ENSXMAP00000011793	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	DNA polymerase.	0.744
dtl	pold2	ENSXMAP00000017536	ENSXMAP00000015386	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Polymerase (DNA directed), delta 2, regulatory subunit.	0.696
dtl	pole2	ENSXMAP00000017536	ENSXMAP00000008217	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.781
dtl	rev3l	ENSXMAP00000017536	ENSXMAP00000025535	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.628
pclaf	dtl	ENSXMAP00000032017	ENSXMAP00000017536	PCNA clamp associated factor.	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	0.599
pclaf	pcna	ENSXMAP00000032017	ENSXMAP00000014924	PCNA clamp associated factor.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.958
pclaf	pold1	ENSXMAP00000032017	ENSXMAP00000011793	PCNA clamp associated factor.	DNA polymerase.	0.488
pclaf	pold2	ENSXMAP00000032017	ENSXMAP00000015386	PCNA clamp associated factor.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.614
pclaf	pole2	ENSXMAP00000032017	ENSXMAP00000008217	PCNA clamp associated factor.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.619
pclaf	rev3l	ENSXMAP00000032017	ENSXMAP00000025535	PCNA clamp associated factor.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.402
pcna	LOC102234371	ENSXMAP00000014924	ENSXMAP00000012347	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Zgc:136908; Belongs to the AAA ATPase family.	0.654
pcna	dtl	ENSXMAP00000014924	ENSXMAP00000017536	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	0.972
pcna	pclaf	ENSXMAP00000014924	ENSXMAP00000032017	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	PCNA clamp associated factor.	0.958