70 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102232653	Uncharacterized protein. (732 aa)
	LOC102233784	Kelch-like family member 40a. (613 aa)
	M3ZGC4_XIPMA	Axin 2 (conductin, axil). (885 aa)
	LOC102236343	RBR-type E3 ubiquitin transferase. (274 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	rnf14	RBR-type E3 ubiquitin transferase. (482 aa)
	bbs7	Bardet-Biedl syndrome 7. (713 aa)
	dda1	DET1 and DDB1 associated 1. (102 aa)
	fbxw8	F-box and WD repeat domain containing 8. (651 aa)
	LOC111609723	RBR-type E3 ubiquitin transferase. (452 aa)
	LOC102222342	Tribbles pseudokinase 1. (361 aa)
	csnk1d	Casein kinase 1, delta b; Belongs to the protein kinase superfamily. (405 aa)
	LOC102229058	RBR-type E3 ubiquitin transferase. (837 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (423 aa)
	LOC102226231	RBR-type E3 ubiquitin transferase. (649 aa)
	dab2	DAB adaptor protein 2. (758 aa)
	det1	DET1 partner of COP1 E3 ubiquitin ligase. (551 aa)
	LOC102231273	Tribbles pseudokinase 3. (351 aa)
	psmd10	Proteasome 26S subunit, non-ATPase 10. (226 aa)
	rnf217	RBR-type E3 ubiquitin transferase. (584 aa)
	LOC102233342	Clusterin; Belongs to the clusterin family. (459 aa)
	LOC102216892	Uncharacterized protein. (836 aa)
	klhl40	Kelch-like family member 40b. (612 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	hspbp1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1. (335 aa)
	sh3rf1	SH3 domain containing ring finger 1. (850 aa)
	nub1	Negative regulator of ubiquitin-like proteins 1. (588 aa)
	ankib1	RBR-type E3 ubiquitin transferase. (1109 aa)
	arih1	RBR-type E3 ubiquitin transferase. (530 aa)
	rnf180	Ring finger protein 180. (484 aa)
	LOC102235963	Casein kinase 1, epsilon; Belongs to the protein kinase superfamily. (439 aa)
	LOC102234612	SH3 domain containing ring finger 3. (843 aa)
	rnf19b	RBR-type E3 ubiquitin transferase. (714 aa)
	LOC102236245	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (433 aa)
	cop1	COP1 E3 ubiquitin ligase. (696 aa)
	FZR1	Fizzy/cell division cycle 20 related 1a. (497 aa)
	arih2	RBR-type E3 ubiquitin transferase. (511 aa)
	LOC102233248	Suppressor of cytokine signaling 9. (548 aa)
	socs5	Suppressor of cytokine signaling 5b. (556 aa)
	axin1	Axin 1. (850 aa)
	fbxo22	F-box protein 22. (384 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2328 aa)
	LOC102225050	Fizzy/cell division cycle 20 related 1b. (487 aa)
	LOC102237237	Mitogen-activated protein kinase. (420 aa)
	rchy1	Ring finger and CHY zinc finger domain containing 1. (272 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC111611018	Uncharacterized protein. (278 aa)
	zyg11b	Zyg-11 homolog (C. elegans). (809 aa)
	gsk3a	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	cdc20	Cell division cycle 20 homolog. (551 aa)
	LOC102223622	RBR-type E3 ubiquitin transferase. (1262 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (413 aa)
	LOC102228538	Clusterin; Belongs to the clusterin family. (464 aa)
	LOC102227874	Uncharacterized protein. (271 aa)
	LOC111611023	Uncharacterized protein. (291 aa)
	ENSXMAP00000032446	Ubiquitin-like domain-containing protein. (138 aa)
	clul1	Clusterin; Belongs to the clusterin family. (415 aa)
	nop53	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (464 aa)
	AXIN2	Axin 2. (791 aa)
	trib2	Tribbles pseudokinase 2. (344 aa)
	rnf144a	RBR-type E3 ubiquitin transferase. (295 aa)
	LOC102227447	Uncharacterized protein. (273 aa)
	LOC102219183	RBR-type E3 ubiquitin transferase. (315 aa)
	csnk1e	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
	ENSXMAP00000038106	Parkin RBR E3 ubiquitin protein ligase. (257 aa)
	zer1	Zyg-11 related, cell cycle regulator. (784 aa)
	sirt6	Sirtuin 6. (390 aa)
	LOC102228925	Uncharacterized protein. (881 aa)
	DDA1	DET1 and DDB1 associated 1. (119 aa)
	rnf19a	RBR-type E3 ubiquitin transferase. (1004 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	LOC102228925	ENSXMAP00000033753	ENSXMAP00000039602	Axin 2.	Uncharacterized protein.	0.924
AXIN2	LOC102235963	ENSXMAP00000033753	ENSXMAP00000016082	Axin 2.	Casein kinase 1, epsilon; Belongs to the protein kinase superfamily.	0.949
AXIN2	LOC102236245	ENSXMAP00000033753	ENSXMAP00000016621	Axin 2.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.794
AXIN2	axin1	ENSXMAP00000033753	ENSXMAP00000020486	Axin 2.	Axin 1.	0.924
AXIN2	csnk1d	ENSXMAP00000033753	ENSXMAP00000003449	Axin 2.	Casein kinase 1, delta b; Belongs to the protein kinase superfamily.	0.515
AXIN2	csnk1e	ENSXMAP00000033753	ENSXMAP00000037889	Axin 2.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.949
AXIN2	gsk3a	ENSXMAP00000033753	ENSXMAP00000026075	Axin 2.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.794
AXIN2	gsk3b	ENSXMAP00000033753	ENSXMAP00000004053	Axin 2.	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.	0.982
DDA1	cop1	ENSXMAP00000041419	ENSXMAP00000018412	DET1 and DDB1 associated 1.	COP1 E3 ubiquitin ligase.	0.664
DDA1	det1	ENSXMAP00000041419	ENSXMAP00000005829	DET1 and DDB1 associated 1.	DET1 partner of COP1 E3 ubiquitin ligase.	0.703
ENSXMAP00000032446	lrrk2	ENSXMAP00000032446	ENSXMAP00000022786	Ubiquitin-like domain-containing protein.	Leucine-rich repeat kinase 2.	0.502
ENSXMAP00000038106	lrrk2	ENSXMAP00000038106	ENSXMAP00000022786	Parkin RBR E3 ubiquitin protein ligase.	Leucine-rich repeat kinase 2.	0.502
FZR1	LOC102225050	ENSXMAP00000019370	ENSXMAP00000023608	Fizzy/cell division cycle 20 related 1a.	Fizzy/cell division cycle 20 related 1b.	0.901
FZR1	cdc20	ENSXMAP00000019370	ENSXMAP00000026611	Fizzy/cell division cycle 20 related 1a.	Cell division cycle 20 homolog.	0.676
FZR1	psmd10	ENSXMAP00000019370	ENSXMAP00000006824	Fizzy/cell division cycle 20 related 1a.	Proteasome 26S subunit, non-ATPase 10.	0.430
LOC102219183	arih2	ENSXMAP00000037054	ENSXMAP00000019405	RBR-type E3 ubiquitin transferase.	RBR-type E3 ubiquitin transferase.	0.436
LOC102222342	cop1	ENSXMAP00000003325	ENSXMAP00000018412	Tribbles pseudokinase 1.	COP1 E3 ubiquitin ligase.	0.617
LOC102222342	det1	ENSXMAP00000003325	ENSXMAP00000005829	Tribbles pseudokinase 1.	DET1 partner of COP1 E3 ubiquitin ligase.	0.421
LOC102223622	arih2	ENSXMAP00000027106	ENSXMAP00000019405	RBR-type E3 ubiquitin transferase.	RBR-type E3 ubiquitin transferase.	0.436
LOC102225050	FZR1	ENSXMAP00000023608	ENSXMAP00000019370	Fizzy/cell division cycle 20 related 1b.	Fizzy/cell division cycle 20 related 1a.	0.901