STRINGSTRING
acss2 acss2 acot8 acot8 LOC102216725 LOC102216725 mlycd mlycd LOC102228484 LOC102228484 elovl5 elovl5 dlat dlat LOC102235415 LOC102235415 GCDH GCDH pipox pipox LOC102219420 LOC102219420 LOC102232461 LOC102232461 LOC102223039 LOC102223039 LOC102231820 LOC102231820 LOC102231519 LOC102231519 LOC102219234 LOC102219234 pdhx pdhx LOC102218120 LOC102218120 fitm2 fitm2 aadat aadat LOC102234334 LOC102234334 LOC102216454 LOC102216454 LOC102216473 LOC102216473 elovl7 elovl7 gpam gpam acsl5 acsl5 LOC102232569 LOC102232569 oxsm oxsm LOC102221879 LOC102221879 LOC102219711 LOC102219711 coasy coasy dcakd dcakd pdha1 pdha1 LOC102217542 LOC102217542 nudt7 nudt7 acot9 acot9 elovl6 elovl6 LOC106699759 LOC106699759 nudt8 nudt8 LOC102220842 LOC102220842 LOC102226141 LOC102226141 LOC102229336 LOC102229336 LOC102236855 LOC102236855 mcee mcee hddc3 hddc3 LOC102234273 LOC102234273 LOC102218182 LOC102218182 aass aass mpc2 mpc2 LOC102231386 LOC102231386 LOC102226402 LOC102226402 LOC102235712 LOC102235712 suclg2 suclg2 acot7 acot7 DLST DLST ppcs ppcs LOC106700092 LOC106700092 LOC102220845 LOC102220845 pmvk pmvk pank4 pank4 LOC102233727 LOC102233727 nudt19 nudt19 LOC111606273 LOC111606273 ENSXMAP00000030548 ENSXMAP00000030548 LOC102233504 LOC102233504 hsd17b4 hsd17b4 ppcdc ppcdc papss1 papss1 LOC102217325 LOC102217325 LOC111609657 LOC111609657 LOC102226920 LOC102226920 tdo2 tdo2 mccc2 mccc2 mvd mvd ACSL1 ACSL1 LOC102229254 LOC102229254 LOC102231902 LOC102231902 LOC102233983 LOC102233983 acsl1 acsl1 LOC102231993 LOC102231993 hmgcr hmgcr crot crot acsl4 acsl4 LOC102231536 LOC102231536 acacb acacb mvk mvk acsl3 acsl3 pdhb pdhb ACLY ACLY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acss2Acyl-CoA synthetase short chain family member 2. (695 aa)
acot8Acyl-CoA thioesterase 8. (337 aa)
LOC102216725Acyl-CoA thioesterase 11b. (576 aa)
mlycdMalonyl-CoA decarboxylase. (504 aa)
LOC102228484ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1101 aa)
elovl5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (645 aa)
LOC102235415Elongation of very long chain fatty acids protein. (272 aa)
GCDHGlutaryl-CoA dehydrogenase b. (440 aa)
pipoxPipecolic acid oxidase. (388 aa)
LOC102219420AMP-binding domain-containing protein. (722 aa)
LOC1022324613'-phosphoadenosine 5'-phosphosulfate synthase 2a. (615 aa)
LOC102223039Uncharacterized protein. (609 aa)
LOC102231820Elongation of very long chain fatty acids protein. (263 aa)
LOC102231519Si:ch211-198n5.11. (565 aa)
LOC102219234Acetyl-CoA carboxylase alpha. (2322 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
LOC102218120Acyl-CoA synthetase long chain family member 2. (699 aa)
fitm2Fat storage inducing transmembrane protein 2. (255 aa)
aadatAminoadipate aminotransferase. (425 aa)
LOC102234334Acyl-CoA synthetase long chain family member 3b. (709 aa)
LOC102216454Pantothenate kinase 1a. (463 aa)
LOC102216473Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (517 aa)
elovl7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (294 aa)
gpamGlycerol-3-phosphate acyltransferase 1, mitochondrial. (818 aa)
acsl5Acyl-CoA synthetase long chain family member 5. (683 aa)
LOC102232569Acyl-CoA thioesterase 16. (421 aa)
oxsm3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (465 aa)
LOC102221879Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (266 aa)
LOC102219711Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (312 aa)
coasyCoA synthase. (557 aa)
dcakdDephospho-CoA kinase domain containing. (229 aa)
pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (455 aa)
LOC102217542Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (304 aa)
nudt7Nudix (nucleoside diphosphate linked moiety X)-type motif 7. (231 aa)
acot9Acyl-CoA thioesterase 9, tandem duplicate 2. (493 aa)
elovl6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (269 aa)
LOC106699759Uncharacterized protein. (152 aa)
nudt8Nudix hydrolase domain-containing protein. (398 aa)
LOC102220842Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (320 aa)
LOC102226141Acetyl-coenzyme A synthetase. (708 aa)
LOC1022293363-hydroxy-3-methylglutaryl coenzyme A reductase. (859 aa)
LOC102236855Pantothenate kinase 2. (431 aa)
mceeMethylmalonyl CoA epimerase. (173 aa)
hddc3HD domain containing 3. (179 aa)
LOC102234273Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
LOC102218182Acetyl-coenzyme A synthetase. (679 aa)
aassAminoadipate-semialdehyde synthase. (930 aa)
mpc2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (120 aa)
LOC102231386Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (269 aa)
LOC102226402Uncharacterized protein. (548 aa)
LOC102235712Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (334 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
acot7Acyl-CoA thioesterase 7. (377 aa)
DLSTDihydrolipoamide S-succinyltransferase. (430 aa)
ppcsPhosphopantothenoylcysteine synthetase. (322 aa)
LOC106700092Uncharacterized protein. (436 aa)
LOC102220845Dihydrolipoamide S-succinyltransferase. (539 aa)
pmvkPhosphomevalonate kinase. (202 aa)
pank4Pantothenate kinase. (774 aa)
LOC102233727Uncharacterized protein. (420 aa)
nudt19Nudix (nucleoside diphosphate linked moiety X)-type motif 19. (393 aa)
LOC111606273Acyl-CoA thioesterase 19. (467 aa)
ENSXMAP00000030548Uncharacterized protein. (165 aa)
LOC102233504Uncharacterized protein. (208 aa)
hsd17b4Hydroxysteroid (17-beta) dehydrogenase 4. (737 aa)
ppcdcPhosphopantothenoylcysteine decarboxylase. (208 aa)
papss13'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa)
LOC102217325Uncharacterized protein. (415 aa)
LOC111609657Uncharacterized protein. (207 aa)
LOC102226920Uncharacterized protein. (193 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (405 aa)
mccc2Methylcrotonoyl-CoA carboxylase 2 (beta). (564 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (686 aa)
LOC102229254Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (517 aa)
LOC102231902Uncharacterized protein. (610 aa)
LOC102233983Uncharacterized protein. (414 aa)
acsl1Acyl-CoA synthetase long chain family member 1a. (698 aa)
LOC1022319933-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (515 aa)
hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa)
crotCarnitine O-octanoyltransferase. (612 aa)
acsl4Acyl-CoA synthetase long chain family member 4a. (665 aa)
LOC102231536Uncharacterized protein. (128 aa)
acacbAcetyl-CoA carboxylase beta. (2263 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
acsl3Uncharacterized protein. (719 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1091 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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