(16 nodes) SMN-Sm protein complex network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gemin4	Gem (nuclear organelle) associated protein 4. (1121 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	ddx20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (766 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	gemin2	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (258 aa)
	gemin6	Gem (nuclear organelle) associated protein 6. (191 aa)
	Snrpf	Small nuclear ribonucleoprotein polypeptide F. (85 aa)
	gemin7	Gem (nuclear organelle) associated protein 7. (128 aa)
	ENSXMAP00000022713	Small nuclear ribonucleoprotein-associated protein. (234 aa)
	gemin5	Gem (nuclear organelle) associated protein 5. (1445 aa)
	gemin8	Gem (nuclear organelle) associated protein 8. (194 aa)
	strap	Serine/threonine kinase receptor associated protein. (329 aa)
	LOC102216861	Survival of motor neuron 1, telomeric. (283 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000022713	LOC102216861	ENSXMAP00000022713	ENSXMAP00000037183	Small nuclear ribonucleoprotein-associated protein.	Survival of motor neuron 1, telomeric.	0.579
ENSXMAP00000022713	Snrpf	ENSXMAP00000022713	ENSXMAP00000015470	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein polypeptide F.	0.927
ENSXMAP00000022713	ddx20	ENSXMAP00000022713	ENSXMAP00000007598	Small nuclear ribonucleoprotein-associated protein.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.474
ENSXMAP00000022713	gemin2	ENSXMAP00000022713	ENSXMAP00000009560	Small nuclear ribonucleoprotein-associated protein.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.401
ENSXMAP00000022713	gemin4	ENSXMAP00000022713	ENSXMAP00000040514	Small nuclear ribonucleoprotein-associated protein.	Gem (nuclear organelle) associated protein 4.	0.451
ENSXMAP00000022713	gemin5	ENSXMAP00000022713	ENSXMAP00000023967	Small nuclear ribonucleoprotein-associated protein.	Gem (nuclear organelle) associated protein 5.	0.526
ENSXMAP00000022713	gemin7	ENSXMAP00000022713	ENSXMAP00000019603	Small nuclear ribonucleoprotein-associated protein.	Gem (nuclear organelle) associated protein 7.	0.488
ENSXMAP00000022713	gemin8	ENSXMAP00000022713	ENSXMAP00000027460	Small nuclear ribonucleoprotein-associated protein.	Gem (nuclear organelle) associated protein 8.	0.475
ENSXMAP00000022713	snrpd1	ENSXMAP00000022713	ENSXMAP00000003379	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.973
ENSXMAP00000022713	snrpd2	ENSXMAP00000022713	ENSXMAP00000001004	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D2.	0.934
ENSXMAP00000022713	snrpd3	ENSXMAP00000022713	ENSXMAP00000001128	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D3.	0.976
ENSXMAP00000022713	snrpe	ENSXMAP00000022713	ENSXMAP00000008868	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.926
ENSXMAP00000022713	snrpg	ENSXMAP00000022713	ENSXMAP00000004358	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein G.	0.898
LOC102216861	ENSXMAP00000022713	ENSXMAP00000037183	ENSXMAP00000022713	Survival of motor neuron 1, telomeric.	Small nuclear ribonucleoprotein-associated protein.	0.579
LOC102216861	Snrpf	ENSXMAP00000037183	ENSXMAP00000015470	Survival of motor neuron 1, telomeric.	Small nuclear ribonucleoprotein polypeptide F.	0.943
LOC102216861	ddx20	ENSXMAP00000037183	ENSXMAP00000007598	Survival of motor neuron 1, telomeric.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.997
LOC102216861	gemin2	ENSXMAP00000037183	ENSXMAP00000009560	Survival of motor neuron 1, telomeric.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.979
LOC102216861	gemin4	ENSXMAP00000037183	ENSXMAP00000040514	Survival of motor neuron 1, telomeric.	Gem (nuclear organelle) associated protein 4.	0.908
LOC102216861	gemin5	ENSXMAP00000037183	ENSXMAP00000023967	Survival of motor neuron 1, telomeric.	Gem (nuclear organelle) associated protein 5.	0.938
LOC102216861	gemin6	ENSXMAP00000037183	ENSXMAP00000014210	Survival of motor neuron 1, telomeric.	Gem (nuclear organelle) associated protein 6.	0.702