(43 nodes) Organ growth network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lepr	Leptin receptor. (1116 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
	LOC102223598	Uncharacterized protein. (685 aa)
	LOC102223216	Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
	LOC102224067	Uncharacterized protein. (82 aa)
	tbx20	T-box transcription factor 20. (440 aa)
	gja1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (387 aa)
	LOC102225231	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
	LOC102218548	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
	LOC102235995	RAP1A, member of RAS oncogene family b. (185 aa)
	LOC102223832	Uncharacterized protein. (184 aa)
	arid2	AT rich interactive domain 2 (ARID, RFX-like). (1667 aa)
	ecm1	Uncharacterized protein. (473 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	LOC102229429	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	utp25	UTP25 small subunit processor component. (748 aa)
	anxa6	Annexin. (666 aa)
	nkx2-5	NK2 homeobox 5. (319 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (539 aa)
	ostn	Uncharacterized protein. (87 aa)
	sav1	Salvador family WW domain containing protein 1. (399 aa)
	M4ARB7_XIPMA	Mesoderm posterior ba. (237 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (395 aa)
	ift80	Intraflagellar transport 80 homolog (Chlamydomonas). (778 aa)
	LOC102235604	Sprouty RTK signaling antagonist 2. (349 aa)
	UBE3A	Ubiquitin protein ligase E3A. (1025 aa)
	LOC102216664	Immediate early response 3 interacting protein 1. (82 aa)
	ENSXMAP00000022372	Uncharacterized protein. (174 aa)
	LOC102226994	Uncharacterized protein. (185 aa)
	adprhl1	ADP-ribosylhydrolase like 1. (1012 aa)
	fxn	Frataxin. (213 aa)
	tsku	Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (370 aa)
	LOC102231514	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (598 aa)
	dipk2a	Divergent protein kinase domain 2Ab. (434 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (720 aa)
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	map2k4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (436 aa)
	ar	Androgen receptor. (754 aa)
	LOC102235488	Ubiquitin protein ligase E3A. (823 aa)
	LOC111611358	Uncharacterized protein. (272 aa)
	EVC	EvC ciliary complex subunit 1. (970 aa)
	LOC102218632	Stanniocalcin 1. (279 aa)
	ENSXMAP00000041784	DUF3496 domain-containing protein. (514 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000022372	LOC102218632	ENSXMAP00000022372	ENSXMAP00000040722	Uncharacterized protein.	Stanniocalcin 1.	0.408
ENSXMAP00000022372	LOC102223598	ENSXMAP00000022372	ENSXMAP00000002905	Uncharacterized protein.	Uncharacterized protein.	0.536
ENSXMAP00000022372	ar	ENSXMAP00000022372	ENSXMAP00000035568	Uncharacterized protein.	Androgen receptor.	0.429
ENSXMAP00000022372	bcl2	ENSXMAP00000022372	ENSXMAP00000034296	Uncharacterized protein.	BCL2 apoptosis regulator b.	0.560
ENSXMAP00000022372	lepr	ENSXMAP00000022372	ENSXMAP00000002254	Uncharacterized protein.	Leptin receptor.	0.890
LOC102218632	ENSXMAP00000022372	ENSXMAP00000040722	ENSXMAP00000022372	Stanniocalcin 1.	Uncharacterized protein.	0.408
LOC102223216	LOC102231514	ENSXMAP00000003201	ENSXMAP00000029495	Transforming growth factor beta; Belongs to the TGF-beta family.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.990
LOC102223216	TGFBR2	ENSXMAP00000003201	ENSXMAP00000014396	Transforming growth factor beta; Belongs to the TGF-beta family.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.990
LOC102223598	ENSXMAP00000022372	ENSXMAP00000002905	ENSXMAP00000022372	Uncharacterized protein.	Uncharacterized protein.	0.536
LOC102223598	ar	ENSXMAP00000002905	ENSXMAP00000035568	Uncharacterized protein.	Androgen receptor.	0.902
LOC102223832	LOC102226994	ENSXMAP00000006551	ENSXMAP00000026714	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC102223832	LOC102235995	ENSXMAP00000006551	ENSXMAP00000006006	Uncharacterized protein.	RAP1A, member of RAS oncogene family b.	0.900
LOC102225231	map2k4	ENSXMAP00000005275	ENSXMAP00000034735	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.900
LOC102226994	LOC102223832	ENSXMAP00000026714	ENSXMAP00000006551	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC102226994	LOC102235995	ENSXMAP00000026714	ENSXMAP00000006006	Uncharacterized protein.	RAP1A, member of RAS oncogene family b.	0.900
LOC102231514	LOC102223216	ENSXMAP00000029495	ENSXMAP00000003201	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.990
LOC102231514	TGFBR2	ENSXMAP00000029495	ENSXMAP00000014396	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.902
LOC102235488	UBE3A	ENSXMAP00000036228	ENSXMAP00000021050	Ubiquitin protein ligase E3A.	Ubiquitin protein ligase E3A.	0.901
LOC102235995	LOC102223832	ENSXMAP00000006006	ENSXMAP00000006551	RAP1A, member of RAS oncogene family b.	Uncharacterized protein.	0.900
LOC102235995	LOC102226994	ENSXMAP00000006006	ENSXMAP00000026714	RAP1A, member of RAS oncogene family b.	Uncharacterized protein.	0.900