57 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102234568	Fragile X mental retardation 1. (602 aa)
	LOC102235407	Anoctamin. (775 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC102228842	PRA1 family protein. (190 aa)
	LOC102233266	PRA1 family protein. (160 aa)
	slc26a5	Solute carrier family 26 member 5. (736 aa)
	LOC102222205	Anoctamin. (771 aa)
	serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (442 aa)
	kcne4	Potassium voltage-gated channel, Isk-related family, member 4. (228 aa)
	sri	Uncharacterized protein. (260 aa)
	pxk	PX domain containing serine/threonine kinase. (569 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (455 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9. (671 aa)
	LOC106699612	Kell metallo-endopeptidase (Kell blood group). (788 aa)
	stk39	Serine threonine kinase 39. (504 aa)
	LOC102227899	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (406 aa)
	gem	GTP binding protein overexpressed in skeletal muscle. (306 aa)
	LOC102234293	Grancalcin. (237 aa)
	LOC102233552	Uncharacterized protein. (1491 aa)
	arl6ip5	PRA1 family protein. (192 aa)
	vip	Vasoactive intestinal peptide. (151 aa)
	Trh	Thyrotropin-releasing hormone. (370 aa)
	cntd1	Cyclin N-terminal domain containing 1. (226 aa)
	LOC102227358	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (386 aa)
	rrad	Ras-related associated with diabetes. (309 aa)
	gopc	Golgi-associated PDZ and coiled-coil motif containing. (445 aa)
	LOC102218345	Uncharacterized protein. (997 aa)
	ENSXMAP00000024215	HECT domain-containing protein. (334 aa)
	LOC102229269	Protein kinase domain-containing protein. (1886 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	Nedd4	HECT domain-containing protein. (106 aa)
	LOC102238336	Oxidative stress responsive kinase 1a. (550 aa)
	LOC102218378	WNK lysine deficient protein kinase 2. (2687 aa)
	ENSXMAP00000028456	Protein kinase domain-containing protein. (535 aa)
	wnk3	Protein kinase domain-containing protein. (3248 aa)
	ENSXMAP00000028941	Uncharacterized protein. (393 aa)
	pawr	PRKC, apoptosis, WT1, regulator. (341 aa)
	LOC102217960	Protein kinase domain-containing protein. (1380 aa)
	ENSXMAP00000032436	C2 domain-containing protein. (320 aa)
	slc30a1	Solute carrier family 30 member 1a. (477 aa)
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	ENSXMAP00000034786	Uncharacterized protein. (134 aa)
	LOC102230771	CACN subunit beta associated regulatory protein b. (899 aa)
	LOC111611948	Uncharacterized protein. (551 aa)
	wnk4	WNK lysine deficient protein kinase 4b. (1466 aa)
	nedd4l	NEDD4 like E3 ubiquitin protein ligase. (1014 aa)
	pln	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (53 aa)
	hecw1	Uncharacterized protein. (1626 aa)
	commd1	Copper metabolism (Murr1) domain containing 1. (190 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	REM1	RRAD and GEM like GTPase 1. (307 aa)
	LOC102235775	WNK lysine deficient protein kinase 1b. (2616 aa)
	nedd4	NEDD4 E3 ubiquitin protein ligase a. (522 aa)
	oxsr1	Oxidative stress responsive kinase 1b. (535 aa)
	LOC102218632	Stanniocalcin 1. (279 aa)
	clic2	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (243 aa)
	ENSXMAP00000041362	Uncharacterized protein. (54 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000024215	ENSXMAP00000032436	ENSXMAP00000024215	ENSXMAP00000032436	HECT domain-containing protein.	C2 domain-containing protein.	0.434
ENSXMAP00000028456	ENSXMAP00000028941	ENSXMAP00000028456	ENSXMAP00000028941	Protein kinase domain-containing protein.	Uncharacterized protein.	0.888
ENSXMAP00000028941	ENSXMAP00000028456	ENSXMAP00000028941	ENSXMAP00000028456	Uncharacterized protein.	Protein kinase domain-containing protein.	0.888
ENSXMAP00000028941	LOC102238336	ENSXMAP00000028941	ENSXMAP00000027430	Uncharacterized protein.	Oxidative stress responsive kinase 1a.	0.479
ENSXMAP00000028941	oxsr1	ENSXMAP00000028941	ENSXMAP00000040529	Uncharacterized protein.	Oxidative stress responsive kinase 1b.	0.479
ENSXMAP00000028941	stk39	ENSXMAP00000028941	ENSXMAP00000011810	Uncharacterized protein.	Serine threonine kinase 39.	0.479
ENSXMAP00000032436	ENSXMAP00000024215	ENSXMAP00000032436	ENSXMAP00000024215	C2 domain-containing protein.	HECT domain-containing protein.	0.434
ENSXMAP00000034786	kcne4	ENSXMAP00000034786	ENSXMAP00000008285	Uncharacterized protein.	Potassium voltage-gated channel, Isk-related family, member 4.	0.479
LOC102217960	LOC102238336	ENSXMAP00000030757	ENSXMAP00000027430	Protein kinase domain-containing protein.	Oxidative stress responsive kinase 1a.	0.479
LOC102217960	oxsr1	ENSXMAP00000030757	ENSXMAP00000040529	Protein kinase domain-containing protein.	Oxidative stress responsive kinase 1b.	0.479
LOC102217960	stk39	ENSXMAP00000030757	ENSXMAP00000011810	Protein kinase domain-containing protein.	Serine threonine kinase 39.	0.479
LOC102225266	cav3	ENSXMAP00000001534	ENSXMAP00000038231	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.593
LOC102227358	drd3	ENSXMAP00000018417	ENSXMAP00000010128	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.645
LOC102227899	drd3	ENSXMAP00000013074	ENSXMAP00000010128	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.645
LOC102229269	LOC102238336	ENSXMAP00000024890	ENSXMAP00000027430	Protein kinase domain-containing protein.	Oxidative stress responsive kinase 1a.	0.479
LOC102229269	oxsr1	ENSXMAP00000024890	ENSXMAP00000040529	Protein kinase domain-containing protein.	Oxidative stress responsive kinase 1b.	0.479
LOC102229269	stk39	ENSXMAP00000024890	ENSXMAP00000011810	Protein kinase domain-containing protein.	Serine threonine kinase 39.	0.479
LOC102235775	LOC102238336	ENSXMAP00000039971	ENSXMAP00000027430	WNK lysine deficient protein kinase 1b.	Oxidative stress responsive kinase 1a.	0.479
LOC102235775	oxsr1	ENSXMAP00000039971	ENSXMAP00000040529	WNK lysine deficient protein kinase 1b.	Oxidative stress responsive kinase 1b.	0.479
LOC102235775	stk39	ENSXMAP00000039971	ENSXMAP00000011810	WNK lysine deficient protein kinase 1b.	Serine threonine kinase 39.	0.479