(11 nodes) Positive T cell selection network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102233430	Interleukin 6 receptor. (611 aa)
	LOC102227782	Uncharacterized protein. (232 aa)
	LOC111611912	Ig_4 domain-containing protein. (164 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1011 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1325 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
	themis2	Thymocyte selection associated family member 2. (702 aa)
	SRF	Serum response factor. (597 aa)
	tbx21	T-box transcription factor 21. (610 aa)
	batf	Basic leucine zipper transcription factor, ATF-like. (124 aa)
	LOC102229912	MADS-box domain-containing protein. (469 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102229912	SRF	ENSXMAP00000035017	ENSXMAP00000021858	MADS-box domain-containing protein.	Serum response factor.	0.903
LOC111611912	PTPRC	ENSXMAP00000002925	ENSXMAP00000002422	Ig_4 domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.739
Mtor	stk11	ENSXMAP00000001362	ENSXMAP00000019378	Serine/threonine-protein kinase TOR.	Serine/threonine kinase 11; Belongs to the protein kinase superfamily.	0.616
PTPRC	LOC111611912	ENSXMAP00000002422	ENSXMAP00000002925	Protein tyrosine phosphatase receptor type C.	Ig_4 domain-containing protein.	0.739
PTPRC	tbx21	ENSXMAP00000002422	ENSXMAP00000027377	Protein tyrosine phosphatase receptor type C.	T-box transcription factor 21.	0.410
SRF	LOC102229912	ENSXMAP00000021858	ENSXMAP00000035017	Serum response factor.	MADS-box domain-containing protein.	0.903
stk11	Mtor	ENSXMAP00000019378	ENSXMAP00000001362	Serine/threonine kinase 11; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase TOR.	0.616
tbx21	PTPRC	ENSXMAP00000027377	ENSXMAP00000002422	T-box transcription factor 21.	Protein tyrosine phosphatase receptor type C.	0.410