31 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102235604	Sprouty RTK signaling antagonist 2. (349 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC102217859	Progestin and adipoQ receptor family member IIIb. (315 aa)
	sorl1	Sortilin-related receptor, L(DLR class) A repeats containing. (2131 aa)
	hmgcr	3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa)
	dusp19	Dual specificity phosphatase 19a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (209 aa)
	nf1	Neurofibromin 1b. (2752 aa)
	LOC102227626	Dual specificity phosphatase 19. (203 aa)
	LOC102232293	Apolipoprotein Ea. (251 aa)
	aida	Axin interactor, dorsalization associated. (304 aa)
	LOC102216911	Apolipoprotein Eb. (265 aa)
	LOC102229336	3-hydroxy-3-methylglutaryl coenzyme A reductase. (859 aa)
	spry1	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (358 aa)
	SPRY3	Sprouty RTK signaling antagonist 3. (294 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (556 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	ptpn5	Protein tyrosine phosphatase non-receptor type 5. (570 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (461 aa)
	tmem130	PKD domain-containing protein. (417 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC102229158	Uncharacterized protein. (341 aa)
	sh2b3	SH2B adaptor protein 3. (708 aa)
	paqr3	Progestin and adipoQ receptor family member IIIa. (411 aa)
	dusp10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
	gba	Glucosylceramidase. (527 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	bmp4	Bone morphogenetic protein 4. (399 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (631 aa)
	ENSXMAP00000039114	Bone morphogenetic protein 16. (511 aa)
	LOC102226565	Si:dkey-175m17.7. (879 aa)
	spry4	Sprouty homolog 4 (Drosophila). (381 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102216911	agt	ENSXMAP00000018640	ENSXMAP00000022683	Apolipoprotein Eb.	Angiotensinogen; Belongs to the serpin family.	0.508
LOC102216911	cav1	ENSXMAP00000018640	ENSXMAP00000025385	Apolipoprotein Eb.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.414
LOC102216911	cav3	ENSXMAP00000018640	ENSXMAP00000038231	Apolipoprotein Eb.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.422
LOC102216911	hmgcr	ENSXMAP00000018640	ENSXMAP00000006510	Apolipoprotein Eb.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.469
LOC102216911	sorl1	ENSXMAP00000018640	ENSXMAP00000005928	Apolipoprotein Eb.	Sortilin-related receptor, L(DLR class) A repeats containing.	0.782
LOC102225266	cav3	ENSXMAP00000001534	ENSXMAP00000038231	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.593
LOC102229336	hmgcr	ENSXMAP00000019034	ENSXMAP00000006510	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.901
LOC102232293	sorl1	ENSXMAP00000016138	ENSXMAP00000005928	Apolipoprotein Ea.	Sortilin-related receptor, L(DLR class) A repeats containing.	0.721
LOC102235604	spry1	ENSXMAP00000020980	ENSXMAP00000020024	Sprouty RTK signaling antagonist 2.	Sprouty homolog 1, antagonist of FGF signaling (Drosophila).	0.629
SPRY3	spry1	ENSXMAP00000020435	ENSXMAP00000020024	Sprouty RTK signaling antagonist 3.	Sprouty homolog 1, antagonist of FGF signaling (Drosophila).	0.568
agt	LOC102216911	ENSXMAP00000022683	ENSXMAP00000018640	Angiotensinogen; Belongs to the serpin family.	Apolipoprotein Eb.	0.508
cav1	LOC102216911	ENSXMAP00000025385	ENSXMAP00000018640	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Apolipoprotein Eb.	0.414
cav1	cav3	ENSXMAP00000025385	ENSXMAP00000038231	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.573
cav3	LOC102216911	ENSXMAP00000038231	ENSXMAP00000018640	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Apolipoprotein Eb.	0.422
cav3	LOC102225266	ENSXMAP00000038231	ENSXMAP00000001534	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.593
cav3	cav1	ENSXMAP00000038231	ENSXMAP00000025385	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.573
gba	smpd1	ENSXMAP00000037324	ENSXMAP00000038735	Glucosylceramidase.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.939
hmgcr	LOC102216911	ENSXMAP00000006510	ENSXMAP00000018640	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Apolipoprotein Eb.	0.469
hmgcr	LOC102229336	ENSXMAP00000006510	ENSXMAP00000019034	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.901
smpd1	gba	ENSXMAP00000038735	ENSXMAP00000037324	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Glucosylceramidase.	0.939