(7 nodes) Double-strand break repair via synthesis-dependent strand annealing network (Xiphophorus maculatus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	rad52	RAD52 homolog, DNA repair protein. (445 aa)
	dmc1	DNA meiotic recombinase 1; Belongs to the RecA family. (274 aa)
	helq	Helicase, POLQ like. (992 aa)
	fancm	Uncharacterized protein. (1911 aa)
	xrcc3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (364 aa)
	rad51c	RAD51 paralog C. (352 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dmc1	fancm	ENSXMAP00000012603	ENSXMAP00000007734	DNA meiotic recombinase 1; Belongs to the RecA family.	Uncharacterized protein.	0.930
dmc1	helq	ENSXMAP00000012603	ENSXMAP00000012584	DNA meiotic recombinase 1; Belongs to the RecA family.	Helicase, POLQ like.	0.406
dmc1	rad51	ENSXMAP00000012603	ENSXMAP00000000592	DNA meiotic recombinase 1; Belongs to the RecA family.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.969
dmc1	rad51c	ENSXMAP00000012603	ENSXMAP00000003353	DNA meiotic recombinase 1; Belongs to the RecA family.	RAD51 paralog C.	0.680
dmc1	rad52	ENSXMAP00000012603	ENSXMAP00000036981	DNA meiotic recombinase 1; Belongs to the RecA family.	RAD52 homolog, DNA repair protein.	0.872
dmc1	xrcc3	ENSXMAP00000012603	ENSXMAP00000007564	DNA meiotic recombinase 1; Belongs to the RecA family.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.974
fancm	dmc1	ENSXMAP00000007734	ENSXMAP00000012603	Uncharacterized protein.	DNA meiotic recombinase 1; Belongs to the RecA family.	0.930
fancm	helq	ENSXMAP00000007734	ENSXMAP00000012584	Uncharacterized protein.	Helicase, POLQ like.	0.846
fancm	rad51	ENSXMAP00000007734	ENSXMAP00000000592	Uncharacterized protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.996
fancm	rad51c	ENSXMAP00000007734	ENSXMAP00000003353	Uncharacterized protein.	RAD51 paralog C.	0.930
fancm	rad52	ENSXMAP00000007734	ENSXMAP00000036981	Uncharacterized protein.	RAD52 homolog, DNA repair protein.	0.997
fancm	xrcc3	ENSXMAP00000007734	ENSXMAP00000007564	Uncharacterized protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.935
helq	dmc1	ENSXMAP00000012584	ENSXMAP00000012603	Helicase, POLQ like.	DNA meiotic recombinase 1; Belongs to the RecA family.	0.406
helq	fancm	ENSXMAP00000012584	ENSXMAP00000007734	Helicase, POLQ like.	Uncharacterized protein.	0.846
helq	rad51	ENSXMAP00000012584	ENSXMAP00000000592	Helicase, POLQ like.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.584
helq	rad51c	ENSXMAP00000012584	ENSXMAP00000003353	Helicase, POLQ like.	RAD51 paralog C.	0.461
helq	rad52	ENSXMAP00000012584	ENSXMAP00000036981	Helicase, POLQ like.	RAD52 homolog, DNA repair protein.	0.466
helq	xrcc3	ENSXMAP00000012584	ENSXMAP00000007564	Helicase, POLQ like.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.427
rad51	dmc1	ENSXMAP00000000592	ENSXMAP00000012603	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	DNA meiotic recombinase 1; Belongs to the RecA family.	0.969
rad51	fancm	ENSXMAP00000000592	ENSXMAP00000007734	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	Uncharacterized protein.	0.996