STRINGSTRING
suclg1 suclg1 idh3a idh3a suclg2 suclg2 DLST DLST LOC102220845 LOC102220845 OGDH OGDH idh3g idh3g Fh Fh ogdh ogdh mrps36 mrps36 dld dld dbt dbt bckdha bckdha bckdhb bckdhb idh3b idh3b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
DLSTDihydrolipoamide S-succinyltransferase. (430 aa)
LOC102220845Dihydrolipoamide S-succinyltransferase. (539 aa)
OGDHOxoglutarate dehydrogenase. (1036 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (396 aa)
FhFumarate hydratase. (494 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1022 aa)
mrps36Mitochondrial ribosomal protein S36. (151 aa)
dldDihydrolipoyl dehydrogenase. (508 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (508 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (447 aa)
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (387 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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