(28 nodes) Late endosome to vacuole transport network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tmem50a	Transmembrane protein 50A. (160 aa)
	pik3r4	Phosphoinositide-3-kinase, regulatory subunit 4. (1325 aa)
	LOC102227507	Charged multivesicular body protein 5b. (220 aa)
	LOC102231495	Charged multivesicular body protein 4C. (233 aa)
	TMEM50B	Transmembrane protein 50B. (159 aa)
	chmp2b	Charged multivesicular body protein 2Bb. (216 aa)
	becn1	Beclin 1, autophagy related. (448 aa)
	chmp1b	Chromatin modifying protein 1B. (199 aa)
	LOC102226311	Charged multivesicular body protein 6a. (207 aa)
	LEPROT	Leptin receptor overlapping transcript. (130 aa)
	chmp6	Charged multivesicular body protein 6. (197 aa)
	chmp2a	Charged multivesicular body protein 2A. (221 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (514 aa)
	LOC102238033	Charged multivesicular body protein 5a. (220 aa)
	ptpn23	Protein tyrosine phosphatase, non-receptor type 23, a. (1872 aa)
	LOC102220940	Charged multivesicular body protein 4Bb. (221 aa)
	LOC102228592	Uncharacterized protein. (229 aa)
	chmp3	Charged multivesicular body protein 3. (221 aa)
	snf8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
	vps25	Vacuolar protein sorting 25 homolog. (175 aa)
	vta1	Vesicle (multivesicular body) trafficking 1. (320 aa)
	leprotl1	Leptin receptor overlapping transcript like 1. (131 aa)
	vps36	Vacuolar protein sorting 36 homolog. (382 aa)
	LOC102231110	Uncharacterized protein. (522 aa)
	chmp7	Charged multivesicular body protein 7. (522 aa)
	LOC102220112	Uncharacterized protein. (223 aa)
	chmp1a	Charged multivesicular body protein 1A. (181 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LEPROT	TMEM50B	ENSXMAP00000041082	ENSXMAP00000007418	Leptin receptor overlapping transcript.	Transmembrane protein 50B.	0.871
LEPROT	tmem50a	ENSXMAP00000041082	ENSXMAP00000036765	Leptin receptor overlapping transcript.	Transmembrane protein 50A.	0.920
LOC102220112	LOC102220940	ENSXMAP00000037259	ENSXMAP00000019207	Uncharacterized protein.	Charged multivesicular body protein 4Bb.	0.901
LOC102220112	LOC102226311	ENSXMAP00000037259	ENSXMAP00000012767	Uncharacterized protein.	Charged multivesicular body protein 6a.	0.847
LOC102220112	LOC102227507	ENSXMAP00000037259	ENSXMAP00000002117	Uncharacterized protein.	Charged multivesicular body protein 5b.	0.834
LOC102220112	LOC102228592	ENSXMAP00000037259	ENSXMAP00000020670	Uncharacterized protein.	Uncharacterized protein.	0.687
LOC102220112	LOC102231110	ENSXMAP00000037259	ENSXMAP00000032079	Uncharacterized protein.	Uncharacterized protein.	0.973
LOC102220112	LOC102231495	ENSXMAP00000037259	ENSXMAP00000002318	Uncharacterized protein.	Charged multivesicular body protein 4C.	0.911
LOC102220112	LOC102238033	ENSXMAP00000037259	ENSXMAP00000016866	Uncharacterized protein.	Charged multivesicular body protein 5a.	0.834
LOC102220112	chmp1a	ENSXMAP00000037259	ENSXMAP00000035886	Uncharacterized protein.	Charged multivesicular body protein 1A.	0.687
LOC102220112	chmp1b	ENSXMAP00000037259	ENSXMAP00000012135	Uncharacterized protein.	Chromatin modifying protein 1B.	0.687
LOC102220112	chmp2a	ENSXMAP00000037259	ENSXMAP00000014922	Uncharacterized protein.	Charged multivesicular body protein 2A.	0.947
LOC102220112	chmp2b	ENSXMAP00000037259	ENSXMAP00000008804	Uncharacterized protein.	Charged multivesicular body protein 2Bb.	0.825
LOC102220112	chmp3	ENSXMAP00000037259	ENSXMAP00000023425	Uncharacterized protein.	Charged multivesicular body protein 3.	0.955
LOC102220112	chmp6	ENSXMAP00000037259	ENSXMAP00000014509	Uncharacterized protein.	Charged multivesicular body protein 6.	0.847
LOC102220112	chmp7	ENSXMAP00000037259	ENSXMAP00000033282	Uncharacterized protein.	Charged multivesicular body protein 7.	0.973
LOC102220112	ptpn23	ENSXMAP00000037259	ENSXMAP00000019184	Uncharacterized protein.	Protein tyrosine phosphatase, non-receptor type 23, a.	0.893
LOC102220112	snf8	ENSXMAP00000037259	ENSXMAP00000023973	Uncharacterized protein.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.877
LOC102220112	vps25	ENSXMAP00000037259	ENSXMAP00000024265	Uncharacterized protein.	Vacuolar protein sorting 25 homolog.	0.857
LOC102220112	vps28	ENSXMAP00000037259	ENSXMAP00000015796	Uncharacterized protein.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.754