STRINGSTRING
LOC102224640 LOC102224640 LOC102230910 LOC102230910 dbh dbh LOC102229327 LOC102229327 insig1 insig1 acer1 acer1 insig2 insig2 mvd mvd LOC102237429 LOC102237429 fdft1 fdft1 idi1 idi1 ippk ippk LOC102222483 LOC102222483 nus1 nus1 pts pts GOT1 GOT1 acer2 acer2 LOC102231993 LOC102231993 pck2 pck2 lss lss hmgcr hmgcr LOC102234938 LOC102234938 itpkb itpkb LOC102237962 LOC102237962 mvk mvk ebp ebp nsdhl nsdhl gch1 gch1 ISYNA1 ISYNA1 pck1 pck1 spr spr dhcr24 dhcr24 prkaa2 prkaa2 LOC102225591 LOC102225591 M4ACM5_XIPMA M4ACM5_XIPMA SPHK1 SPHK1 LOC102225514 LOC102225514 LOC102223418 LOC102223418 LOC102227875 LOC102227875 M4AFP2_XIPMA M4AFP2_XIPMA dhdds dhdds ipmk ipmk LOC102232424 LOC102232424 LOC111609824 LOC111609824 sptlc1 sptlc1 fdps fdps asah2 asah2 prkaa1 prkaa1 LOC102229336 LOC102229336 impa1 impa1 LOC102218848 LOC102218848 acer3 acer3 qdpr qdpr tmem130 tmem130 sphk2 sphk2 itpka itpka srd5a3 srd5a3 asah1 asah1 LOC102238093 LOC102238093 sc5d sc5d CYP27A1 CYP27A1 LOC102221793 LOC102221793 HSD17B7 HSD17B7 r3hdm4 r3hdm4 got1 got1 dhcr7 dhcr7 tm7sf2 tm7sf2 park7 park7 ppip5k1 ppip5k1 dhfr dhfr pmvk pmvk SPHK1-2 SPHK1-2 LOC102224628 LOC102224628 rusc1 rusc1 impad1 impad1 itpkc itpkc gba gba LOC102226768 LOC102226768 PCBD2 PCBD2 lbr lbr
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC102224640Inositol-1-monophosphatase. (284 aa)
LOC102230910Si:dkey-91i10.3; Belongs to the cytochrome P450 family. (534 aa)
dbhDopamine beta-hydroxylase (dopamine beta-monooxygenase). (614 aa)
LOC102229327Kinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (275 aa)
acer1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (237 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
LOC102237429Monooxygenase, DBH-like 1, like. (543 aa)
fdft1Farnesyl-diphosphate farnesyltransferase 1. (417 aa)
idi1Isopentenyl-diphosphate delta isomerase 1. (285 aa)
ippkInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (496 aa)
LOC102222483Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (511 aa)
nus1NUS1 dehydrodolichyl diphosphate synthase subunit. (288 aa)
pts6-pyruvoyl tetrahydrobiopterin synthase. (148 aa)
GOT1Aspartate aminotransferase. (410 aa)
acer2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (277 aa)
LOC1022319933-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (515 aa)
pck2Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (635 aa)
lssTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (735 aa)
hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa)
LOC102234938Uncharacterized protein; Belongs to the cytochrome P450 family. (509 aa)
itpkbKinase; Belongs to the inositol phosphokinase (IPK) family. (787 aa)
LOC102237962Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. (519 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
ebpEBP cholestenol delta-isomerase. (229 aa)
nsdhlNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (345 aa)
gch1GTP cyclohydrolase 1. (255 aa)
ISYNA1Inositol-3-phosphate synthase 1. (555 aa)
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
sprSepiapterin reductase b. (265 aa)
dhcr2424-dehydrocholesterol reductase. (517 aa)
prkaa2Non-specific serine/threonine protein kinase. (629 aa)
LOC102225591Hydroxysteroid (17-beta) dehydrogenase 7. (375 aa)
M4ACM5_XIPMAKinase; Belongs to the inositol phosphokinase (IPK) family. (414 aa)
SPHK1Sphingosine kinase 1. (564 aa)
LOC102225514Uncharacterized protein; Belongs to the cytochrome P450 family. (536 aa)
LOC102223418Kinase; Belongs to the inositol phosphokinase (IPK) family. (391 aa)
LOC102227875Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1068 aa)
M4AFP2_XIPMAPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (360 aa)
dhddsAlkyl transferase; Belongs to the UPP synthase family. (335 aa)
ipmkKinase; Belongs to the inositol phosphokinase (IPK) family. (478 aa)
LOC102232424Cytochrome P450, family 51; Belongs to the cytochrome P450 family. (495 aa)
LOC111609824GTP cyclohydrolase 2. (236 aa)
sptlc1Serine palmitoyltransferase, long chain base subunit 1. (472 aa)
fdpsUncharacterized protein; Belongs to the FPP/GGPP synthase family. (358 aa)
asah2Neutral ceramidase. (725 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
LOC1022293363-hydroxy-3-methylglutaryl coenzyme A reductase. (859 aa)
impa1Inositol-1-monophosphatase. (279 aa)
LOC102218848Kinase; Belongs to the inositol phosphokinase (IPK) family. (489 aa)
acer3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
qdprQuinoid dihydropteridine reductase a. (235 aa)
tmem130PKD domain-containing protein. (417 aa)
sphk2Sphingosine kinase 2. (898 aa)
itpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (452 aa)
srd5a3Steroid 5 alpha-reductase 3. (315 aa)
asah1N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family. (355 aa)
LOC102238093GTP_cyclohydroI domain-containing protein. (164 aa)
sc5dSterol-C5-desaturase; Belongs to the sterol desaturase family. (292 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
LOC102221793Inositol-1-monophosphatase. (351 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (371 aa)
r3hdm4R3H domain containing 4. (255 aa)
got1Aspartate aminotransferase. (410 aa)
dhcr77-dehydrocholesterol reductase. (485 aa)
tm7sf2Transmembrane 7 superfamily member 2. (424 aa)
park7Parkinson protein 7. (189 aa)
ppip5k1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1416 aa)
dhfrDihydrofolate reductase. (208 aa)
pmvkPhosphomevalonate kinase. (202 aa)
SPHK1-2Sphingosine kinase 1. (548 aa)
LOC102224628Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha. (174 aa)
rusc1Uncharacterized protein. (1574 aa)
impad1Inositol monophosphatase domain containing 1. (344 aa)
itpkcKinase; Belongs to the inositol phosphokinase (IPK) family. (676 aa)
gbaGlucosylceramidase. (527 aa)
LOC102226768Kinase; Belongs to the inositol phosphokinase (IPK) family. (300 aa)
PCBD2Pterin-4 alpha-carbinolamine dehydratase 2. (136 aa)
lbrLamin B receptor. (684 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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