(22 nodes) Barbed-end actin filament capping network (Xiphophorus maculatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	LOC102234185	Advillin. (816 aa)
	capzb	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
	flii	FLII actin remodeling protein. (1271 aa)
	gsn	Gelsolin a. (740 aa)
	LOC102218977	Scinderin like a. (704 aa)
	LOC102217170	Scinderin like b. (720 aa)
	add2	Adducin 2 (beta). (668 aa)
	svil	Supervillin a. (1686 aa)
	LOC102223273	HP domain-containing protein. (1683 aa)
	LOC102218227	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	M4A121_XIPMA	Uncharacterized protein. (373 aa)
	vill	Villin-like. (845 aa)
	LOC102225023	Adducin 3 (gamma) b. (694 aa)
	CAPZA2	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	capg	Capping protein (actin filament), gelsolin-like b. (344 aa)
	LOC102223222	Twinfilin actin-binding protein 2b. (368 aa)
	LOC102237670	Supervillin c. (1590 aa)
	add1	Adducin 1 (alpha). (900 aa)
	LOC102223302	Supervillin d. (1482 aa)
	LOC102216510	Adducin 3 (gamma) a. (685 aa)
	LOC102216475	Twinfilin actin-binding protein 1a. (429 aa)
	twf2	Twinfilin actin-binding protein 2a. (352 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAPZA2	LOC102216475	ENSXMAP00000014507	ENSXMAP00000039475	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Twinfilin actin-binding protein 1a.	0.588
CAPZA2	LOC102218227	ENSXMAP00000014507	ENSXMAP00000007625	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.901
CAPZA2	LOC102223222	ENSXMAP00000014507	ENSXMAP00000020517	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Twinfilin actin-binding protein 2b.	0.588
CAPZA2	capzb	ENSXMAP00000014507	ENSXMAP00000000225	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.987
CAPZA2	twf2	ENSXMAP00000014507	ENSXMAP00000041515	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Twinfilin actin-binding protein 2a.	0.588
LOC102216475	CAPZA2	ENSXMAP00000039475	ENSXMAP00000014507	Twinfilin actin-binding protein 1a.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.588
LOC102216475	LOC102218227	ENSXMAP00000039475	ENSXMAP00000007625	Twinfilin actin-binding protein 1a.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.588
LOC102216475	M4A121_XIPMA	ENSXMAP00000039475	ENSXMAP00000008165	Twinfilin actin-binding protein 1a.	Uncharacterized protein.	0.456
LOC102216475	capg	ENSXMAP00000039475	ENSXMAP00000015743	Twinfilin actin-binding protein 1a.	Capping protein (actin filament), gelsolin-like b.	0.456
LOC102216475	capzb	ENSXMAP00000039475	ENSXMAP00000000225	Twinfilin actin-binding protein 1a.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.844
LOC102216475	gsn	ENSXMAP00000039475	ENSXMAP00000001871	Twinfilin actin-binding protein 1a.	Gelsolin a.	0.456
LOC102216510	add1	ENSXMAP00000039019	ENSXMAP00000031952	Adducin 3 (gamma) a.	Adducin 1 (alpha).	0.596
LOC102216510	capzb	ENSXMAP00000039019	ENSXMAP00000000225	Adducin 3 (gamma) a.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.462
LOC102217170	LOC102218977	ENSXMAP00000004059	ENSXMAP00000003141	Scinderin like b.	Scinderin like a.	0.901
LOC102217170	gsn	ENSXMAP00000004059	ENSXMAP00000001871	Scinderin like b.	Gelsolin a.	0.901
LOC102218227	CAPZA2	ENSXMAP00000007625	ENSXMAP00000014507	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.901
LOC102218227	LOC102216475	ENSXMAP00000007625	ENSXMAP00000039475	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Twinfilin actin-binding protein 1a.	0.588
LOC102218227	LOC102223222	ENSXMAP00000007625	ENSXMAP00000020517	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Twinfilin actin-binding protein 2b.	0.588
LOC102218227	capzb	ENSXMAP00000007625	ENSXMAP00000000225	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.987
LOC102218227	twf2	ENSXMAP00000007625	ENSXMAP00000041515	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Twinfilin actin-binding protein 2a.	0.588