STRINGSTRING
LOC111608394 LOC111608394 LOC111608392 LOC111608392 LOC102218011 LOC102218011 rnf220 rnf220 ripor1 ripor1 clic2 clic2 LOC102235349 LOC102235349 LOC102237354 LOC102237354 ENSXMAP00000041362 ENSXMAP00000041362 tnfsf11 tnfsf11 LOC102237823 LOC102237823 LOC102231586 LOC102231586 LOC102234568 LOC102234568 LOC102216881 LOC102216881 LOC102232368 LOC102232368 LOC102225266 LOC102225266 LOC102229876 LOC102229876 LOC102230901 LOC102230901 LOC102230716 LOC102230716 M3ZJA3_XIPMA M3ZJA3_XIPMA poldip2 poldip2 abl2 abl2 ctsz ctsz gmnn gmnn ripor2 ripor2 dtnbp1 dtnbp1 LOC102235592 LOC102235592 il10 il10 grem2 grem2 LOC102226271 LOC102226271 e2f1 e2f1 c9orf72 c9orf72 LOC102228719 LOC102228719 myocd myocd dab2 dab2 pex19 pex19 lrpap1 lrpap1 sympk sympk sorl1 sorl1 LOC102231273 LOC102231273 LOC102232687 LOC102232687 psme3ip1 psme3ip1 gtpbp4 gtpbp4 disc1 disc1 spon1 spon1 rsf1 rsf1 gnl3l gnl3l zmpste24 zmpste24 LOC102219010 LOC102219010 ercc4 ercc4 men1 men1 itgb1bp1 itgb1bp1 kdm1a kdm1a sri sri derl1 derl1 BAX BAX LOC106700271 LOC106700271 bag2 bag2 gemin2 gemin2 LOC102226082 LOC102226082 LOC106699693 LOC106699693 smo smo frmd7 frmd7 pcsk9 pcsk9 gpsm1 gpsm1 dhx9 dhx9 edf1 edf1 mitd1 mitd1 dhrs7b dhrs7b ripor3 ripor3 LOC102231621 LOC102231621 tdg tdg LOC102223318 LOC102223318 pkd1 pkd1 LOC102234293 LOC102234293 gtf2f1 gtf2f1 LOC102216509 LOC102216509 ZNF462 ZNF462 LOC102226068 LOC102226068 LOC102225599 LOC102225599 nvl nvl LOC102237504 LOC102237504 pin1 pin1 M4ANT8_XIPMA M4ANT8_XIPMA LOC102232293 LOC102232293 hmga2 hmga2 LOC102231945 LOC102231945 ddit3 ddit3 wapl wapl M4AVN4_XIPMA M4AVN4_XIPMA LOC102216911 LOC102216911 taf10 taf10 cdk5 cdk5 M4AWS5_XIPMA M4AWS5_XIPMA ldlrap1 ldlrap1 LOC102225323 LOC102225323 ENSXMAP00000021456 ENSXMAP00000021456 RNF220 RNF220 abl1 abl1 ccpg1 ccpg1 ENSXMAP00000021832 ENSXMAP00000021832 LOC102234982 LOC102234982 lrrk2 lrrk2 igf1 igf1 ENSXMAP00000023172 ENSXMAP00000023172 snapin snapin rapgef2 rapgef2 LOC102232031 LOC102232031 styx styx ski ski LOC102233506 LOC102233506 spag8 spag8 LOC102234067 LOC102234067 cav1 cav1 LOC111608400 LOC111608400 pinx1 pinx1 znf618 znf618 pygo2 pygo2 msx1 msx1 ENSXMAP00000026839 ENSXMAP00000026839 nfatc4 nfatc4 ENSXMAP00000026989 ENSXMAP00000026989 LOC111608395 LOC111608395 TFAP4 TFAP4 ENSXMAP00000027405 ENSXMAP00000027405 ENSXMAP00000027674 ENSXMAP00000027674 pex14 pex14 sirt2 sirt2 gtf2b gtf2b LOC111608656 LOC111608656 lef1 lef1 dot1l dot1l LOC102221305 LOC102221305 ctnnbip1 ctnnbip1 LOC111608408 LOC111608408 rb1 rb1 LOC102234776 LOC102234776 SMAD4 SMAD4 adnp adnp ENSXMAP00000031706 ENSXMAP00000031706 Cldn5 Cldn5 vtn vtn LOC102218934 LOC102218934 ENSXMAP00000032446 ENSXMAP00000032446 LOC102235912 LOC102235912 LOC102230616 LOC102230616 cln5 cln5 LOC102230139 LOC102230139 ercc2 ercc2 larp6 larp6 LOC111608404 LOC111608404 HAND1 HAND1 ENSXMAP00000034376 ENSXMAP00000034376 nek2 nek2 ENSXMAP00000034569 ENSXMAP00000034569 HABP4 HABP4 LOC111605806 LOC111605806 ENSXMAP00000035630 ENSXMAP00000035630 ttbk1 ttbk1 LOC111608410 LOC111608410 Btaf1 Btaf1 LOC111608407 LOC111608407 LOC111608411 LOC111608411 ENSXMAP00000036380 ENSXMAP00000036380 LOC111607606 LOC111607606 LOC102233635 LOC102233635 cthrc1 cthrc1 pln pln LOC102231357 LOC102231357 ENSXMAP00000037404 ENSXMAP00000037404 LOC111608406 LOC111608406 sppl3 sppl3 bambi bambi ttbk2 ttbk2 ENSXMAP00000038106 ENSXMAP00000038106 LOC111608401 LOC111608401 ripk2 ripk2 bmp4 bmp4 LOC102229242 LOC102229242 znf593 znf593 cdt1 cdt1 LOC102223432 LOC102223432 efhb efhb ENSXMAP00000039101 ENSXMAP00000039101 ENSXMAP00000039114 ENSXMAP00000039114
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111608394Uncharacterized protein. (222 aa)
LOC111608392Phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein-like. (222 aa)
LOC102218011Uncharacterized protein. (2410 aa)
rnf220Ring finger protein 220a. (366 aa)
ripor1RHO family interacting cell polarization regulator 1. (1039 aa)
clic2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (243 aa)
LOC102235349PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (570 aa)
LOC102237354Ankyrin repeat domain 33Aa. (450 aa)
ENSXMAP00000041362Uncharacterized protein. (54 aa)
tnfsf11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
LOC102237823Low density lipoprotein receptor adaptor protein 1a. (310 aa)
LOC102231586Ankyrin repeat domain 33ba. (533 aa)
LOC102234568Fragile X mental retardation 1. (602 aa)
LOC102216881Transforming growth factor beta; Belongs to the TGF-beta family. (394 aa)
LOC102232368Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (522 aa)
LOC102225266Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
LOC102229876Thioredoxin; Belongs to the thioredoxin family. (107 aa)
LOC102230901Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
LOC102230716Ankyrin repeat domain 33Ab. (441 aa)
M3ZJA3_XIPMAEpidermal growth factor. (946 aa)
poldip2Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
abl2Tyrosine-protein kinase. (1187 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
gmnnGeminin DNA replication inhibitor. (216 aa)
ripor2RHO family interacting cell polarization regulator 2. (1072 aa)
dtnbp1Dystrobrevin binding protein 1b. (227 aa)
LOC102235592E1A binding protein p300 b. (2751 aa)
il10Interleukin 10. (181 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (192 aa)
LOC102226271JunE proto-oncogene, AP-1 transcription factor subunit. (324 aa)
e2f1E2F transcription factor 1. (456 aa)
c9orf72Zgc:100846. (462 aa)
LOC102228719Mothers against decapentaplegic homolog. (503 aa)
myocdSAP domain-containing protein. (967 aa)
dab2DAB adaptor protein 2. (758 aa)
pex19Peroxisomal biogenesis factor 19. (292 aa)
lrpap1Low density lipoprotein receptor-related protein associated protein 1. (347 aa)
sympkSymplekin. (1214 aa)
sorl1Sortilin-related receptor, L(DLR class) A repeats containing. (2131 aa)
LOC102231273Tribbles pseudokinase 3. (351 aa)
LOC102232687Uncharacterized protein. (493 aa)
psme3ip1Family with sequence similarity 192 member A. (252 aa)
gtpbp4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (637 aa)
disc1DISC1 scaffold protein. (704 aa)
spon1Spondin 1a. (806 aa)
rsf1PHD-type domain-containing protein. (1371 aa)
gnl3lGuanine nucleotide binding protein-like 3 (nucleolar)-like. (557 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
LOC102219010Vitronectin b. (444 aa)
ercc4Excision repair cross-complementation group 4. (893 aa)
men1Multiple endocrine neoplasia I. (626 aa)
itgb1bp1Integrin beta 1 binding protein 1. (198 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (830 aa)
sriUncharacterized protein. (260 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (255 aa)
BAXBCL2 associated X, apoptosis regulator. (190 aa)
LOC106700271Uncharacterized protein. (207 aa)
bag2BCL2 associated athanogene 2. (208 aa)
gemin2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (258 aa)
LOC102226082E1A binding protein p300 a. (2737 aa)
LOC106699693Zgc:66440. (368 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
frmd7FERM domain containing 7. (297 aa)
pcsk9Proprotein convertase subtilisin/kexin type 9. (671 aa)
gpsm1G protein signaling modulator 1b. (662 aa)
dhx9DEAH (Asp-Glu-Ala-His) box helicase 9. (1246 aa)
edf1Endothelial differentiation-related factor 1. (148 aa)
mitd1MIT, microtubule interacting and transport, domain containing 1. (246 aa)
dhrs7bDehydrogenase/reductase (SDR family) member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (307 aa)
ripor3RIPOR family member 3. (974 aa)
LOC102231621WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b. (575 aa)
tdgThymine DNA glycosylase, tandem duplicate 1. (492 aa)
LOC102223318Thymine DNA glycosylase, tandem duplicate 2. (411 aa)
pkd1Polycystic kidney disease 1a. (4563 aa)
LOC102234293Grancalcin. (237 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (497 aa)
LOC102216509Info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a. (573 aa)
ZNF462Zinc finger protein 462. (2545 aa)
LOC102226068WAPL cohesin release factor b. (1230 aa)
LOC102225599Protein S100; Belongs to the S-100 family. (100 aa)
nvlNuclear VCP like. (815 aa)
LOC102237504Uncharacterized protein. (782 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (208 aa)
M4ANT8_XIPMAClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
LOC102232293Apolipoprotein Ea. (251 aa)
hmga2Uncharacterized protein. (114 aa)
LOC102231945Tau tubulin kinase 2b. (425 aa)
ddit3DNA-damage-inducible transcript 3. (311 aa)
waplWAPL cohesin release factor a. (1176 aa)
M4AVN4_XIPMARing finger protein 220b. (217 aa)
LOC102216911Apolipoprotein Eb. (265 aa)
taf10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
M4AWS5_XIPMAUncharacterized protein. (602 aa)
ldlrap1Low density lipoprotein receptor adaptor protein 1b. (312 aa)
LOC102225323Mothers against decapentaplegic homolog. (563 aa)
ENSXMAP00000021456RING-type domain-containing protein. (380 aa)
RNF220Uncharacterized protein. (233 aa)
abl1Tyrosine-protein kinase. (1152 aa)
ccpg1Uncharacterized protein. (854 aa)
ENSXMAP00000021832RING-type domain-containing protein. (313 aa)
LOC102234982Dickkopf WNT signaling pathway inhibitor 1a. (279 aa)
lrrk2Leucine-rich repeat kinase 2. (2328 aa)
igf1Insulin-like growth factor 1. (186 aa)
ENSXMAP00000023172Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (288 aa)
snapinSNAP associated protein. (129 aa)
rapgef2Rap guanine nucleotide exchange factor (GEF) 2. (1621 aa)
LOC102232031Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (300 aa)
styxSerine/threonine/tyrosine interacting protein. (202 aa)
skiV-ski avian sarcoma viral oncogene homolog a. (718 aa)
LOC102233506Si:dkey-3h3.3. (432 aa)
spag8Sperm associated antigen 8. (181 aa)
LOC102234067Remodeling and spacing factor 1b, tandem duplicate 1. (1856 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
LOC111608400Uncharacterized protein. (218 aa)
pinx1PIN2 (TERF1) interacting telomerase inhibitor 1. (419 aa)
znf618Zinc finger protein 618. (917 aa)
pygo2Pygopus homolog 2 (Drosophila). (583 aa)
msx1Muscle segment homeobox 1a. (281 aa)
ENSXMAP00000026839PWWP domain-containing protein. (143 aa)
nfatc4Nuclear factor of activated T cells 4. (842 aa)
ENSXMAP00000026989Uncharacterized protein. (206 aa)
LOC111608395Uncharacterized protein. (222 aa)
TFAP4Transcription factor AP-4. (334 aa)
ENSXMAP00000027405DUF4939 domain-containing protein. (149 aa)
ENSXMAP00000027674Uncharacterized protein. (273 aa)
pex14Peroxisomal biogenesis factor 14. (374 aa)
sirt2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (413 aa)
gtf2bGeneral transcription factor IIB. (318 aa)
LOC111608656Zgc:113363. (223 aa)
lef1Lymphoid enhancer-binding factor 1. (379 aa)
dot1lHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1583 aa)
LOC102221305GATA binding protein 1a. (438 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
LOC111608408Uncharacterized protein. (218 aa)
rb1Retinoblastoma susceptibility protein. (912 aa)
LOC102234776RING-type domain-containing protein. (198 aa)
SMAD4Mothers against decapentaplegic homolog. (512 aa)
adnpActivity-dependent neuroprotector homeobox b. (1055 aa)
ENSXMAP00000031706Uncharacterized protein. (190 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (165 aa)
vtnVitronectin a. (567 aa)
LOC102218934Nuclear receptor binding SET domain protein 1a. (2166 aa)
ENSXMAP00000032446Ubiquitin-like domain-containing protein. (138 aa)
LOC102235912Ankyrin repeat domain 33Bb. (529 aa)
LOC102230616Uncharacterized protein. (345 aa)
cln5CLN5 intracellular trafficking protein. (294 aa)
LOC102230139Thioredoxin; Belongs to the thioredoxin family. (108 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
larp6La ribonucleoprotein domain family, member 6a. (716 aa)
LOC111608404Uncharacterized protein. (204 aa)
HAND1Heart and neural crest derivatives expressed 1. (194 aa)
ENSXMAP00000034376RING-type domain-containing protein. (328 aa)
nek2NIMA-related kinase 2. (438 aa)
ENSXMAP00000034569Uncharacterized protein. (208 aa)
HABP4Hyaluronan binding protein 4. (393 aa)
LOC111605806RING-type domain-containing protein. (260 aa)
ENSXMAP00000035630Muscle segment homeobox 3. (147 aa)
ttbk1Tau tubulin kinase 1a. (1280 aa)
LOC111608410Uncharacterized protein. (218 aa)
Btaf1Uncharacterized protein. (216 aa)
LOC111608407Uncharacterized protein. (175 aa)
LOC111608411Uncharacterized LOC111608411. (218 aa)
ENSXMAP00000036380PL48 domain-containing protein. (312 aa)
LOC111607606Uncharacterized protein. (323 aa)
LOC102233635Inhibitor of DNA binding 1, HLH protein. (127 aa)
cthrc1Collagen triple helix repeat containing 1b. (229 aa)
plnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (53 aa)
LOC102231357Transcription factor AP-4 (activating enhancer binding protein 4). (329 aa)
ENSXMAP00000037404Uncharacterized protein. (166 aa)
LOC111608406Uncharacterized protein. (200 aa)
sppl3Signal peptide peptidase 3. (391 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
ttbk2Tau tubulin kinase 2a. (1220 aa)
ENSXMAP00000038106Parkin RBR E3 ubiquitin protein ligase. (257 aa)
LOC111608401Uncharacterized protein. (217 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (584 aa)
bmp4Bone morphogenetic protein 4. (399 aa)
LOC102229242Uncharacterized protein. (296 aa)
znf593Zinc finger protein 593. (129 aa)
cdt1Chromatin licensing and DNA replication factor 1. (761 aa)
LOC102223432Uncharacterized protein. (309 aa)
efhbUncharacterized protein. (557 aa)
ENSXMAP00000039101UPAR/Ly6 domain-containing protein. (150 aa)
ENSXMAP00000039114Bone morphogenetic protein 16. (511 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
Server load: low (22%) [HD]