STRINGSTRING
klhdc3 klhdc3 piwil1 piwil1 rad51 rad51 mos mos MCMDC2 MCMDC2 fancd2 fancd2 espl1 espl1 SGO1 SGO1 rad51c rad51c LOC102224556 LOC102224556 KIF18A KIF18A incenp incenp mre11 mre11 M3ZPQ6_XIPMA M3ZPQ6_XIPMA Terb1 Terb1 smc2 smc2 LOC102224900 LOC102224900 ncapd3 ncapd3 rbbp8 rbbp8 bub1b bub1b sycp3 sycp3 brca2 brca2 nbn nbn smc3 smc3 ttk ttk fancm fancm Meioc Meioc ercc4 ercc4 tdrd1 tdrd1 majin majin M4A3H1_XIPMA M4A3H1_XIPMA Atrx Atrx LOC102220833 LOC102220833 ednra ednra EME2 EME2 mus81 mus81 ncaph ncaph LOC102226637 LOC102226637 RPA1 RPA1 C1orf146 C1orf146 smc1a smc1a LOC102218059 LOC102218059 top2a top2a ncapd2 ncapd2 rad51d rad51d LOC102236202 LOC102236202 eme1 eme1 meiob meiob LOC102233674 LOC102233674 Cenpx Cenpx dmc1 dmc1 stk35 stk35 ndc1 ndc1 hus1 hus1 sirt7 sirt7 msh5 msh5 LOC102221997 LOC102221997 bag6 bag6 LOC102217509 LOC102217509 tubg1 tubg1 trip13 trip13 exd1 exd1 asz1 asz1 LOC102222551 LOC102222551 tubgcp2 tubgcp2 tdrkh tdrkh rmi1 rmi1 ercc1 ercc1 tubgcp5 tubgcp5 spire2 spire2 edn1 edn1 bub3 bub3 LOC102221752 LOC102221752 atm atm top2b top2b LOC102224555 LOC102224555 pld6 pld6 spo11 spo11 tubgcp4 tubgcp4 tdrd9 tdrd9 smc4 smc4 psmd13 psmd13 slc4a1ap slc4a1ap pkmyt1 pkmyt1 LOC102223278 LOC102223278 terb2 terb2 ENSXMAP00000021046 ENSXMAP00000021046 ENSXMAP00000021083 ENSXMAP00000021083 LOC111608004 LOC111608004 ENSXMAP00000021866 ENSXMAP00000021866 ccne2 ccne2 LOC102231624 LOC102231624 ENSXMAP00000022343 ENSXMAP00000022343 ENSXMAP00000023613 ENSXMAP00000023613 ENSXMAP00000023735 ENSXMAP00000023735 FBXO43 FBXO43 ENSXMAP00000024369 ENSXMAP00000024369 ENSXMAP00000025155 ENSXMAP00000025155 ENSXMAP00000025425 ENSXMAP00000025425 ENSXMAP00000025468 ENSXMAP00000025468 slx4 slx4 ENSXMAP00000025960 ENSXMAP00000025960 ENSXMAP00000025991 ENSXMAP00000025991 mns1 mns1 ankle1 ankle1 mlh1 mlh1 EDNRA EDNRA piwil2 piwil2 ENSXMAP00000028253 ENSXMAP00000028253 LOC102224158 LOC102224158 ENSXMAP00000028709 ENSXMAP00000028709 ENSXMAP00000028786 ENSXMAP00000028786 MARF1 MARF1 LOC102217065 LOC102217065 LOC111611385 LOC111611385 psmc3ip psmc3ip rec8 rec8 rad1 rad1 ENSXMAP00000030751 ENSXMAP00000030751 numa1 numa1 hsf2bp hsf2bp syce3 syce3 ENSXMAP00000031216 ENSXMAP00000031216 ENSXMAP00000031223 ENSXMAP00000031223 msh4 msh4 ENSXMAP00000031754 ENSXMAP00000031754 ENSXMAP00000031814 ENSXMAP00000031814 LOC111607145 LOC111607145 LOC111610367 LOC111610367 mlh3 mlh3 ENSXMAP00000032264 ENSXMAP00000032264 ENSXMAP00000032514 ENSXMAP00000032514 ENSXMAP00000032676 ENSXMAP00000032676 ENSXMAP00000032679 ENSXMAP00000032679 ENSXMAP00000032715 ENSXMAP00000032715 ENSXMAP00000032734 ENSXMAP00000032734 ENSXMAP00000033187 ENSXMAP00000033187 ENSXMAP00000033576 ENSXMAP00000033576 ccnb1ip1 ccnb1ip1 YTHDC2 YTHDC2 ENSXMAP00000035484 ENSXMAP00000035484 Ncaph2 Ncaph2 ENSXMAP00000035974 ENSXMAP00000035974 ENSXMAP00000036521 ENSXMAP00000036521 ENSXMAP00000036593 ENSXMAP00000036593 rpa1 rpa1 ENSXMAP00000036808 ENSXMAP00000036808 ENSXMAP00000036829 ENSXMAP00000036829 fkbp6 fkbp6 LOC102219904 LOC102219904 ENSXMAP00000038311 ENSXMAP00000038311 LOC102221792 LOC102221792 LOC102228467 LOC102228467 ENSXMAP00000038993 ENSXMAP00000038993 mnd1 mnd1 ENSXMAP00000039404 ENSXMAP00000039404 fbxo5 fbxo5 rad50 rad50 ENSXMAP00000039864 ENSXMAP00000039864 ENSXMAP00000039893 ENSXMAP00000039893 ENSXMAP00000040204 ENSXMAP00000040204 ENSXMAP00000040306 ENSXMAP00000040306 Tubgcp3 Tubgcp3 Bub1 Bub1 ENSXMAP00000040970 ENSXMAP00000040970 pdik1l pdik1l bcl2l11 bcl2l11 LOC102222899 LOC102222899 ENSXMAP00000041423 ENSXMAP00000041423
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
klhdc3Kelch domain containing 3. (382 aa)
piwil1Piwi-like RNA-mediated gene silencing 1; Belongs to the argonaute family. (833 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
mosV-mos Moloney murine sarcoma viral oncogene homolog; Belongs to the protein kinase superfamily. (337 aa)
MCMDC2Minichromosome maintenance domain containing 2. (649 aa)
fancd2FA complementation group D2. (1235 aa)
espl1Extra spindle pole bodies like 1, separase. (2165 aa)
SGO1Shugoshin_C domain-containing protein. (636 aa)
rad51cRAD51 paralog C. (352 aa)
LOC102224556Uncharacterized protein. (192 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (876 aa)
incenpUncharacterized protein. (752 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (743 aa)
M3ZPQ6_XIPMAHelicase for meiosis 1. (869 aa)
Terb1Uncharacterized protein. (337 aa)
smc2Structural maintenance of chromosomes protein. (1200 aa)
LOC102224900Wee1-like protein kinase. (526 aa)
ncapd3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1404 aa)
rbbp8Uncharacterized protein. (638 aa)
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (430 aa)
sycp3Synaptonemal complex protein 3. (238 aa)
brca2BRCA2 DNA repair associated. (3052 aa)
nbnNibrin. (831 aa)
smc3Structural maintenance of chromosomes protein. (1217 aa)
ttkTtk protein kinase. (916 aa)
fancmUncharacterized protein. (1911 aa)
MeiocUncharacterized protein. (219 aa)
ercc4Excision repair cross-complementation group 4. (893 aa)
tdrd1Tudor domain containing 1. (1095 aa)
majinMembrane anchored junction protein. (241 aa)
M4A3H1_XIPMAHORMA domain containing 1. (241 aa)
AtrxATRX chromatin remodeler. (1195 aa)
LOC102220833Structural maintenance of chromosomes protein. (1237 aa)
ednraEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (444 aa)
EME2ERCC4 domain-containing protein. (438 aa)
mus81MUS81 structure-specific endonuclease subunit. (617 aa)
ncaphCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (726 aa)
LOC102226637EGF-like domain-containing protein. (153 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (700 aa)
C1orf146Chromosome 1 open reading frame 146. (172 aa)
smc1aStructural maintenance of chromosomes protein. (1231 aa)
LOC102218059Baculoviral IAP repeat containing 5a. (142 aa)
top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1536 aa)
ncapd2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1370 aa)
rad51dRAD51 paralog D. (339 aa)
LOC102236202Bromodomain, testis-specific. (916 aa)
eme1Essential meiotic structure-specific endonuclease 1. (536 aa)
meiobMethionine sulfoxide reductase B1b. (425 aa)
LOC102233674Uncharacterized protein. (1901 aa)
CenpxUncharacterized protein. (63 aa)
dmc1DNA meiotic recombinase 1; Belongs to the RecA family. (274 aa)
stk35Serine/threonine kinase 35; Belongs to the protein kinase superfamily. (421 aa)
ndc1NDC1 transmembrane nucleoporin. (669 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (271 aa)
sirt7Sirtuin 7. (408 aa)
msh5MutS homolog 5. (787 aa)
LOC102221997Testis expressed 11. (807 aa)
bag6BCL2 associated athanogene 6. (1212 aa)
LOC102217509Uncharacterized protein. (177 aa)
tubg1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa)
trip13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (420 aa)
exd13'-5' exonuclease domain-containing protein. (481 aa)
asz1Ankyrin repeat, SAM and basic leucine zipper domain containing 1. (421 aa)
LOC102222551Marker of proliferation Ki-67. (1766 aa)
tubgcp2Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (870 aa)
tdrkhTudor and KH domain containing. (539 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (680 aa)
ercc1Excision repair cross-complementation group 1. (350 aa)
tubgcp5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (984 aa)
spire2Spire-type actin nucleation factor 2. (771 aa)
edn1Endothelin 1. (197 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
LOC102221752Fork-head domain-containing protein. (601 aa)
atmATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2875 aa)
top2bDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1589 aa)
LOC102224555Forkhead box J3. (604 aa)
pld6Phospholipase D family, member 6. (216 aa)
spo11SPO11 initiator of meiotic double stranded breaks. (387 aa)
tubgcp4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (667 aa)
tdrd9Tudor domain containing 9. (1268 aa)
smc4Structural maintenance of chromosomes protein. (1326 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
slc4a1apSolute carrier family 4 member 1 adaptor protein. (751 aa)
pkmyt1Protein kinase, membrane associated tyrosine/threonine 1. (577 aa)
LOC102223278Spire-type actin nucleation factor 1a. (789 aa)
terb2Telomere repeat binding bouquet formation protein 2. (211 aa)
ENSXMAP00000021046DDE_3 domain-containing protein. (158 aa)
ENSXMAP00000021083Histone H2A; Belongs to the histone H2A family. (133 aa)
LOC111608004Uncharacterized protein. (329 aa)
ENSXMAP00000021866DDE_3 domain-containing protein. (145 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (394 aa)
LOC102231624SUN domain-containing protein. (597 aa)
ENSXMAP00000022343Histone H2A; Belongs to the histone H2A family. (137 aa)
ENSXMAP00000023613Uncharacterized protein. (333 aa)
ENSXMAP00000023735Uncharacterized protein. (366 aa)
FBXO43F-box protein 43. (692 aa)
ENSXMAP00000024369Uncharacterized protein. (387 aa)
ENSXMAP00000025155Uncharacterized protein. (331 aa)
ENSXMAP00000025425Tudor domain containing 12. (989 aa)
ENSXMAP00000025468Uncharacterized protein. (223 aa)
slx4BTB domain-containing protein. (1245 aa)
ENSXMAP00000025960Histone H2A; Belongs to the histone H2A family. (135 aa)
ENSXMAP00000025991annotation not available (331 aa)
mns1Meiosis-specific nuclear structural 1. (487 aa)
ankle1Zgc:85936. (1142 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (754 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (475 aa)
piwil2Piwi-like RNA-mediated gene silencing 2; Belongs to the argonaute family. (1054 aa)
ENSXMAP00000028253Si:dkey-40g16.5. (135 aa)
LOC102224158Baculoviral IAP repeat containing 5b. (148 aa)
ENSXMAP00000028709Uncharacterized protein. (78 aa)
ENSXMAP00000028786annotation not available (331 aa)
MARF1Meiosis regulator and mRNA stability factor 1. (1769 aa)
LOC102217065RRM domain-containing protein. (335 aa)
LOC111611385Uncharacterized protein. (612 aa)
psmc3ipPSMC3 interacting protein. (220 aa)
rec8Uncharacterized protein. (541 aa)
rad1RAD1 homolog (S. pombe). (289 aa)
ENSXMAP00000030751Histone H2A; Belongs to the histone H2A family. (139 aa)
numa1Calponin-homology (CH) domain-containing protein. (2533 aa)
hsf2bpHeat shock transcription factor 2 binding protein. (338 aa)
syce3Uncharacterized protein. (98 aa)
ENSXMAP00000031216DDE_3 domain-containing protein. (165 aa)
ENSXMAP00000031223Histone H2A; Belongs to the histone H2A family. (122 aa)
msh4DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (912 aa)
ENSXMAP00000031754Uncharacterized protein. (244 aa)
ENSXMAP00000031814Uncharacterized protein. (331 aa)
LOC111607145Uncharacterized protein. (362 aa)
LOC111610367ANK_REP_REGION domain-containing protein. (488 aa)
mlh3MutL homolog 3 (E. coli). (1151 aa)
ENSXMAP00000032264Uncharacterized protein. (331 aa)
ENSXMAP00000032514Uncharacterized protein. (331 aa)
ENSXMAP00000032676Uncharacterized protein. (272 aa)
ENSXMAP00000032679Uncharacterized protein. (387 aa)
ENSXMAP00000032715Uncharacterized protein. (297 aa)
ENSXMAP00000032734Uncharacterized protein. (331 aa)
ENSXMAP00000033187Uncharacterized protein. (331 aa)
ENSXMAP00000033576Histone H2A; Belongs to the histone H2A family. (141 aa)
ccnb1ip1Cyclin B1 interacting protein 1. (264 aa)
YTHDC2YTH domain containing 2. (1398 aa)
ENSXMAP00000035484Zebrafish testis-expressed 38. (263 aa)
Ncaph2CNDH2_N domain-containing protein. (56 aa)
ENSXMAP00000035974annotation not available (331 aa)
ENSXMAP00000036521DDE_3 domain-containing protein. (201 aa)
ENSXMAP00000036593Histone H2A; Belongs to the histone H2A family. (139 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
ENSXMAP00000036808HTH_Tnp_Tc3_2 domain-containing protein. (260 aa)
ENSXMAP00000036829Uncharacterized protein. (329 aa)
fkbp6Peptidylprolyl isomerase. (328 aa)
LOC102219904Spire-type actin nucleation factor 1b. (883 aa)
ENSXMAP00000038311Uncharacterized protein. (297 aa)
LOC102221792UF2 component of NDC80 kinetochore complex. (449 aa)
LOC102228467SUN domain-containing protein. (853 aa)
ENSXMAP00000038993Uncharacterized protein. (335 aa)
mnd1Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (199 aa)
ENSXMAP00000039404HTH_Tnp_Tc3_2 domain-containing protein. (238 aa)
fbxo5F-box protein 5. (409 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
ENSXMAP00000039864annotation not available (331 aa)
ENSXMAP00000039893Si:ch1073-75f15.2. (113 aa)
ENSXMAP00000040204HTH_Tnp_Tc3_2 domain-containing protein. (181 aa)
ENSXMAP00000040306Uncharacterized protein. (102 aa)
Tubgcp3Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (351 aa)
Bub1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (210 aa)
ENSXMAP00000040970Uncharacterized protein. (331 aa)
pdik1lPDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily. (354 aa)
bcl2l11Uncharacterized protein. (250 aa)
LOC102222899Sad1 and UNC84 domain containing 1. (1039 aa)
ENSXMAP00000041423PR domain containing 9. (740 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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