(19 nodes) Mitochondrial calcium ion homeostasis network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	c4h19orf12	Si:ch211-260e23.8. (141 aa)
	disc1	DISC1 scaffold protein. (704 aa)
	maip1	Matrix AAA peptidase interacting protein 1. (241 aa)
	SLC8B1	Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (586 aa)
	letm1	Leucine zipper-EF-hand containing transmembrane protein 1. (769 aa)
	anxa6	Annexin. (666 aa)
	MCUB	Mitochondrial calcium uniporter dominant negative beta subunit. (336 aa)
	immt	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (766 aa)
	micu3	Mitochondrial calcium uptake family, member 3a. (513 aa)
	LOC102233143	Zgc:112052. (141 aa)
	mcu	Mitochondrial calcium uniporter. (467 aa)
	LOC102220931	Uncharacterized protein. (99 aa)
	LOC102219932	Uncharacterized protein. (312 aa)
	micu2	Mitochondrial calcium uptake 2. (423 aa)
	letm2	Leucine zipper-EF-hand containing transmembrane protein 2. (495 aa)
	LOC106699635	Uncharacterized protein. (313 aa)
	smdt1	Single-pass membrane protein with aspartate-rich tail 1a. (129 aa)
	LOC102228745	Mitochondrial calcium uptake family, member 3b. (452 aa)
	micu1	Mitochondrial calcium uptake 1. (485 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102219932	LOC102228745	ENSXMAP00000035272	ENSXMAP00000040320	Uncharacterized protein.	Mitochondrial calcium uptake family, member 3b.	0.485
LOC102219932	MCUB	ENSXMAP00000035272	ENSXMAP00000010219	Uncharacterized protein.	Mitochondrial calcium uniporter dominant negative beta subunit.	0.475
LOC102219932	mcu	ENSXMAP00000035272	ENSXMAP00000029190	Uncharacterized protein.	Mitochondrial calcium uniporter.	0.475
LOC102219932	micu1	ENSXMAP00000035272	ENSXMAP00000041652	Uncharacterized protein.	Mitochondrial calcium uptake 1.	0.656
LOC102219932	micu2	ENSXMAP00000035272	ENSXMAP00000036843	Uncharacterized protein.	Mitochondrial calcium uptake 2.	0.650
LOC102219932	micu3	ENSXMAP00000035272	ENSXMAP00000020686	Uncharacterized protein.	Mitochondrial calcium uptake family, member 3a.	0.485
LOC102220931	LOC102228745	ENSXMAP00000029334	ENSXMAP00000040320	Uncharacterized protein.	Mitochondrial calcium uptake family, member 3b.	0.723
LOC102220931	LOC106699635	ENSXMAP00000029334	ENSXMAP00000039104	Uncharacterized protein.	Uncharacterized protein.	0.587
LOC102220931	MCUB	ENSXMAP00000029334	ENSXMAP00000010219	Uncharacterized protein.	Mitochondrial calcium uniporter dominant negative beta subunit.	0.891
LOC102220931	maip1	ENSXMAP00000029334	ENSXMAP00000007219	Uncharacterized protein.	Matrix AAA peptidase interacting protein 1.	0.587
LOC102220931	mcu	ENSXMAP00000029334	ENSXMAP00000029190	Uncharacterized protein.	Mitochondrial calcium uniporter.	0.891
LOC102220931	micu1	ENSXMAP00000029334	ENSXMAP00000041652	Uncharacterized protein.	Mitochondrial calcium uptake 1.	0.969
LOC102220931	micu2	ENSXMAP00000029334	ENSXMAP00000036843	Uncharacterized protein.	Mitochondrial calcium uptake 2.	0.941
LOC102220931	micu3	ENSXMAP00000029334	ENSXMAP00000020686	Uncharacterized protein.	Mitochondrial calcium uptake family, member 3a.	0.723
LOC102228745	LOC102219932	ENSXMAP00000040320	ENSXMAP00000035272	Mitochondrial calcium uptake family, member 3b.	Uncharacterized protein.	0.485
LOC102228745	LOC102220931	ENSXMAP00000040320	ENSXMAP00000029334	Mitochondrial calcium uptake family, member 3b.	Uncharacterized protein.	0.723
LOC102228745	MCUB	ENSXMAP00000040320	ENSXMAP00000010219	Mitochondrial calcium uptake family, member 3b.	Mitochondrial calcium uniporter dominant negative beta subunit.	0.699
LOC102228745	mcu	ENSXMAP00000040320	ENSXMAP00000029190	Mitochondrial calcium uptake family, member 3b.	Mitochondrial calcium uniporter.	0.699
LOC102228745	micu1	ENSXMAP00000040320	ENSXMAP00000041652	Mitochondrial calcium uptake family, member 3b.	Mitochondrial calcium uptake 1.	0.859
LOC102228745	micu2	ENSXMAP00000040320	ENSXMAP00000036843	Mitochondrial calcium uptake family, member 3b.	Mitochondrial calcium uptake 2.	0.721