STRINGSTRING
jph1 jph1 LOC102234809 LOC102234809 LOC102234568 LOC102234568 jph2 jph2 LOC102232368 LOC102232368 LOC102225266 LOC102225266 LOC102238210 LOC102238210 LOC102229810 LOC102229810 STAC2 STAC2 trpc1 trpc1 LOC102233799 LOC102233799 LOC102227826 LOC102227826 LOC102216997 LOC102216997 M3ZNF2_XIPMA M3ZNF2_XIPMA LOC102226226 LOC102226226 calm3 calm3 LOC102233017 LOC102233017 wfs1 wfs1 spg11 spg11 htt htt jph3 jph3 CACNG1 CACNG1 LOC102229436 LOC102229436 SLC8B1 SLC8B1 selenon selenon pla2g6 pla2g6 sri sri LOC102227992 LOC102227992 pik3cg pik3cg BAX BAX cacnb4 cacnb4 LOC102217712 LOC102217712 stim2 stim2 LOC102223545 LOC102223545 grin3b grin3b il16 il16 LOC102217699 LOC102217699 ENSXMAP00000041362 ENSXMAP00000041362 LOC102235349 LOC102235349 clic2 clic2 LOC102218632 LOC102218632 LOC102218580 LOC102218580 saraf saraf REM1 REM1 gpr161 gpr161 f2 f2 efhb efhb LOC102233260 LOC102233260 r3hdm2 r3hdm2 drd3 drd3 LOC102230071 LOC102230071 LOC102221379 LOC102221379 LOC102231598 LOC102231598 LOC102222536 LOC102222536 cacng6 cacng6 plcg2 plcg2 LOC102220272 LOC102220272 LOC102220803 LOC102220803 p2rx5 p2rx5 LOC102223594 LOC102223594 LOC102234834 LOC102234834 LOC102227899 LOC102227899 gem gem LOC102226965 LOC102226965 tspan13 tspan13 LOC102234293 LOC102234293 orai1 orai1 LOC102237380 LOC102237380 LOC102219692 LOC102219692 LOC102228576 LOC102228576 F2RL3 F2RL3 plcg1 plcg1 rcvrn rcvrn LOC102227511 LOC102227511 LOC102222190 LOC102222190 LOC102233539 LOC102233539 LOC102227358 LOC102227358 HOMER1 HOMER1 LOC102236966 LOC102236966 cdk5 cdk5 LOC102228816 LOC102228816 rrad rrad M4AYC6_XIPMA M4AYC6_XIPMA LOC102227203 LOC102227203 ucn ucn LOC102238149 LOC102238149 cask cask calm1 calm1 LOC102225000 LOC102225000 atg5 atg5 LOC102224922 LOC102224922 nos1ap nos1ap LOC102220074 LOC102220074 LOC102218345 LOC102218345 LOC102220640 LOC102220640 LOC102226976 LOC102226976 LOC102220830 LOC102220830 cav1 cav1 ENSXMAP00000025589 ENSXMAP00000025589 gramd2a gramd2a ENSXMAP00000026658 ENSXMAP00000026658 LOC102219145 LOC102219145 akap6 akap6 LOC102217954 LOC102217954 LOC106699894 LOC106699894 LOC102229956 LOC102229956 pawr pawr LOC102227674 LOC102227674 LOC102231851 LOC102231851 p2rx1 p2rx1 LOC102225994 LOC102225994 LOC102218864 LOC102218864 LOC102226926 LOC102226926 slc30a1 slc30a1 LOC102232483 LOC102232483 LOC102232874 LOC102232874 homer3 homer3 LOC102235421 LOC102235421 LOC102222344 LOC102222344 fkbp1b fkbp1b bcl2 bcl2 HOMER2 HOMER2 LOC102227792 LOC102227792 LOC102220700 LOC102220700 LOC102237383 LOC102237383 LOC102226335 LOC102226335 LOC102230771 LOC102230771 LOC111611948 LOC111611948 cacnb1 cacnb1 stac3 stac3 cacnb2 cacnb2 pln pln stac stac LOC102216870 LOC102216870 cav3 cav3 RAMP3 RAMP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
jph1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (693 aa)
LOC102234809Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (489 aa)
LOC102234568Fragile X mental retardation 1. (602 aa)
jph2Junctophilin 2. (827 aa)
LOC102232368Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (522 aa)
LOC102225266Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
LOC102238210Zgc:153993. (189 aa)
LOC1022298101-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1309 aa)
STAC2SH3 and cysteine rich domain 2. (429 aa)
trpc1Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (765 aa)
LOC102233799Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (410 aa)
LOC102227826SH3 and cysteine rich domain 2. (399 aa)
LOC102216997Uncharacterized protein. (640 aa)
M3ZNF2_XIPMASi:ch211-247i17.1. (119 aa)
LOC102226226Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (415 aa)
calm3Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC102233017Calcium channel, voltage-dependent, beta 4b subunit. (510 aa)
wfs1Wolfram syndrome 1b (wolframin). (964 aa)
spg11SPG11 vesicle trafficking associated, spatacsin. (2399 aa)
httHuntingtin. (2603 aa)
jph3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (786 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (230 aa)
LOC102229436Stromal interaction molecule 1b. (868 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (586 aa)
selenonSelenoprotein N. (554 aa)
pla2g6Phospholipase A2, group VI (cytosolic, calcium-independent). (821 aa)
sriUncharacterized protein. (260 aa)
LOC102227992WH1 domain-containing protein. (363 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1121 aa)
BAXBCL2 associated X, apoptosis regulator. (190 aa)
cacnb4Calcium channel, voltage-dependent, beta 4a subunit. (519 aa)
LOC102217712Uncharacterized protein. (452 aa)
stim2Stromal interaction molecule 2b. (753 aa)
LOC102223545Glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1337 aa)
grin3bGlutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1216 aa)
il16Uncharacterized protein. (614 aa)
LOC102217699C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (372 aa)
ENSXMAP00000041362Uncharacterized protein. (54 aa)
LOC102235349PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (570 aa)
clic2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (243 aa)
LOC102218632Stanniocalcin 1. (279 aa)
LOC102218580Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (942 aa)
sarafStore-operated calcium entry-associated regulatory factor. (374 aa)
REM1RRAD and GEM like GTPase 1. (307 aa)
gpr161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (542 aa)
f2Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (614 aa)
efhbUncharacterized protein. (557 aa)
LOC102233260Stromal interaction molecule 1a. (673 aa)
r3hdm2R3H domain containing 2. (1100 aa)
drd3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (455 aa)
LOC102230071Uncharacterized protein. (282 aa)
LOC102221379Calcium channel, voltage-dependent, beta 3b. (265 aa)
LOC102231598Calcium release activated channel regulator 2Ab. (655 aa)
LOC102222536Calcium binding protein 5b. (167 aa)
cacng6Calcium channel, voltage-dependent, gamma subunit 6b. (266 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1247 aa)
LOC102220272Tromal interaction molecule 2a. (1059 aa)
LOC102220803Wolfram syndrome 1a (wolframin). (1039 aa)
p2rx5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (457 aa)
LOC102223594Nitric oxide synthase 1 (neuronal) adaptor protein b. (517 aa)
LOC102234834Galectin. (402 aa)
LOC102227899G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (406 aa)
gemGTP binding protein overexpressed in skeletal muscle. (306 aa)
LOC102226965Uncharacterized protein. (464 aa)
tspan13Tetraspanin 13a; Belongs to the tetraspanin (TM4SF) family. (220 aa)
LOC102234293Grancalcin. (237 aa)
orai1ORAI calcium release-activated calcium modulator 1b. (223 aa)
LOC102237380Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (228 aa)
LOC102219692Galectin. (248 aa)
LOC102228576Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (375 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (395 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1306 aa)
rcvrnRecoverin a. (203 aa)
LOC102227511Calcium channel, voltage-dependent, beta 2b. (610 aa)
LOC102222190Peptidylprolyl isomerase. (108 aa)
LOC102233539Purinergic receptor P2X, ligand-gated ion channel, 7. (622 aa)
LOC102227358Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (386 aa)
HOMER1Homer scaffold protein 1. (356 aa)
LOC102236966Calcium binding protein 2a. (277 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
LOC102228816Zgc:171965; Belongs to the G-protein coupled receptor 1 family. (431 aa)
rradRas-related associated with diabetes. (309 aa)
M4AYC6_XIPMAG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (413 aa)
LOC102227203Apelin receptor b; Belongs to the G-protein coupled receptor 1 family. (356 aa)
ucnUrotensin 1. (148 aa)
LOC102238149Recoverin 3. (192 aa)
caskUncharacterized protein; Belongs to the MAGUK family. (940 aa)
calm1Calmodulin 1. (149 aa)
LOC102225000Si:dkey-70p6.1. (468 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (326 aa)
LOC102224922Uncharacterized protein. (224 aa)
nos1apPID domain-containing protein. (753 aa)
LOC102220074Uncharacterized protein. (566 aa)
LOC102218345Uncharacterized protein. (997 aa)
LOC102220640Calcium binding protein 1a. (434 aa)
LOC102226976Calcium release activated channel regulator 2A. (720 aa)
LOC102220830Si:dkey-211g8.9. (262 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
ENSXMAP00000025589Uncharacterized protein. (97 aa)
gramd2aGRAM domain containing 2A. (362 aa)
ENSXMAP00000026658Uncharacterized protein. (104 aa)
LOC102219145Cytochrome b-245, alpha polypeptide. (194 aa)
akap6A kinase (PRKA) anchor protein 6. (2530 aa)
LOC102217954C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (345 aa)
LOC106699894C-C motif chemokine. (151 aa)
LOC102229956R3H domain containing 1. (1024 aa)
pawrPRKC, apoptosis, WT1, regulator. (341 aa)
LOC102227674Si:dkey-34e4.1. (663 aa)
LOC102231851Homer scaffold protein 1b. (402 aa)
p2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (432 aa)
LOC102225994Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1103 aa)
LOC102218864SCY domain-containing protein. (141 aa)
LOC102226926Calcium channel, voltage-dependent, gamma subunit 6a. (287 aa)
slc30a1Solute carrier family 30 member 1a. (477 aa)
LOC102232483Calcium binding protein 5a. (162 aa)
LOC102232874Calcium channel, voltage-dependent, beta 3a. (567 aa)
homer3Homer scaffold protein 3b. (366 aa)
LOC102235421C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (374 aa)
LOC102222344Recoverin 2. (193 aa)
fkbp1bPeptidylprolyl isomerase. (110 aa)
bcl2BCL2 apoptosis regulator b. (229 aa)
HOMER2Homer scaffold protein 2. (353 aa)
LOC102227792Galectin. (348 aa)
LOC102220700Si:ch211-146m13.3. (857 aa)
LOC102237383Calcium binding protein 2b. (167 aa)
LOC102226335Peptidylprolyl isomerase. (177 aa)
LOC102230771CACN subunit beta associated regulatory protein b. (899 aa)
LOC111611948Uncharacterized protein. (551 aa)
cacnb1Calcium channel, voltage-dependent, beta 1 subunit. (670 aa)
stac3SH3 and cysteine rich domain 3. (351 aa)
cacnb2Calcium channel, voltage-dependent, beta 2a. (697 aa)
plnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (53 aa)
stacSH3 and cysteine rich domain. (446 aa)
LOC102216870Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (503 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
RAMP3Receptor activity modifying protein 3. (165 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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