83 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (692 aa)
	LOC102224517	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa)
	ENSXMAP00000030259	HMG box domain-containing protein. (227 aa)
	lef1	Lymphoid enhancer-binding factor 1. (379 aa)
	LOC102228480	acidPPc domain-containing protein. (307 aa)
	LOC102232337	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
	scyl2	SCY1 like pseudokinase 2. (920 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	LOC102236316	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (399 aa)
	LOC102229158	Uncharacterized protein. (341 aa)
	LOC102235344	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	ENSXMAP00000026472	DIX domain-containing protein. (55 aa)
	LOC102238407	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
	pygo2	Pygopus homolog 2 (Drosophila). (583 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC102231203	DIX domain containing 1a. (462 aa)
	LOC102234982	Dickkopf WNT signaling pathway inhibitor 1a. (279 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC102234936	Uncharacterized protein. (768 aa)
	LOC106700021	Uncharacterized protein. (370 aa)
	M4B140_XIPMA	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (562 aa)
	LOC102237243	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	Fzd10	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	Fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
	sostdc1	Sclerostin domain containing 1a. (277 aa)
	LOC102233479	Dishevelled segment polarity protein 3a. (686 aa)
	LOC102233666	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	LOC102230049	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (420 aa)
	Fzd9	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
	KCTD15	Potassium channel tetramerization domain containing 15. (265 aa)
	edn1	Endothelin 1. (197 aa)
	dvl2	Dishevelled segment polarity protein 2. (763 aa)
	LOC102216940	Uncharacterized protein. (603 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	LOC102218641	HMG box domain-containing protein. (371 aa)
	wnt10b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (429 aa)
	plpp3	Phospholipid phosphatase 3. (312 aa)
	LOC102217780	DIX domain containing 1. (641 aa)
	fzd3	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family. (678 aa)
	sfrp1	Secreted frizzled-related protein 1a. (306 aa)
	LOC102228256	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	LOC102237039	Homeobox domain-containing protein. (192 aa)
	eda	Ectodysplasin A; Belongs to the tumor necrosis factor family. (368 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (444 aa)
	Wnt16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (240 aa)
	LOC102223878	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	LOC102229429	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	bcl9l	Bcl9 like. (1406 aa)
	WNT7A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (368 aa)
	frzb	Frizzled related protein. (313 aa)
	disc1	DISC1 scaffold protein. (704 aa)
	LOC102218548	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
	wnt9a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
	M3ZR57_XIPMA	Sizzled. (293 aa)
	LOC102222598	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (469 aa)
	wnt2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	LOC102229577	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	lrp6	Low density lipoprotein receptor-related protein 6. (1610 aa)
	sfrp5	Secreted frizzled-related protein 5. (318 aa)
	LOC102225926	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	LOC102234111	Transcription factor 7 like 1b. (582 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC102227689	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
	reck	Reversion-inducing-cysteine-rich protein with kazal motifs. (999 aa)
	LOC102226016	Junction plakoglobin a. (721 aa)
	wnt8b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
	KCTD15-2	Potassium channel tetramerization domain containing 15. (295 aa)
	ENSXMAP00000031276	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (382 aa)
	tcf7l2	Transcription factor 7 like 2. (637 aa)
	dvl1	Dishevelled segment polarity protein 1a. (720 aa)
	tcf7	Transcription factor 7. (528 aa)
	LOC102226870	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (417 aa)
	wnt3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	ENSXMAP00000035407	FZ domain-containing protein. (199 aa)
	LOC102238120	Uncharacterized protein. (917 aa)
	lrp5	Low density lipoprotein receptor-related protein 5. (1649 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	LOC102228510	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDNRA	LOC102222598	ENSXMAP00000027944	ENSXMAP00000004532	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.575
EDNRA	LOC102226870	ENSXMAP00000027944	ENSXMAP00000032282	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.573
EDNRA	LOC102230049	ENSXMAP00000027944	ENSXMAP00000017600	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.571
EDNRA	edn1	ENSXMAP00000027944	ENSXMAP00000016173	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.996
EDNRA	ednra	ENSXMAP00000027944	ENSXMAP00000009624	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.903
ENSXMAP00000026472	ENSXMAP00000035407	ENSXMAP00000026472	ENSXMAP00000035407	DIX domain-containing protein.	FZ domain-containing protein.	0.536
ENSXMAP00000026472	Fzd10	ENSXMAP00000026472	ENSXMAP00000020135	DIX domain-containing protein.	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	0.547
ENSXMAP00000026472	Fzd8	ENSXMAP00000026472	ENSXMAP00000019636	DIX domain-containing protein.	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.480
ENSXMAP00000026472	Fzd9	ENSXMAP00000026472	ENSXMAP00000017131	DIX domain-containing protein.	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.	0.547
ENSXMAP00000026472	LOC102218548	ENSXMAP00000026472	ENSXMAP00000005991	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.433
ENSXMAP00000026472	LOC102223878	ENSXMAP00000026472	ENSXMAP00000009222	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.453
ENSXMAP00000026472	LOC102225926	ENSXMAP00000026472	ENSXMAP00000002620	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.566
ENSXMAP00000026472	LOC102226016	ENSXMAP00000026472	ENSXMAP00000039861	DIX domain-containing protein.	Junction plakoglobin a.	0.598
ENSXMAP00000026472	LOC102227689	ENSXMAP00000026472	ENSXMAP00000001349	DIX domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.480
ENSXMAP00000026472	LOC102228256	ENSXMAP00000026472	ENSXMAP00000010484	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.508
ENSXMAP00000026472	LOC102228510	ENSXMAP00000026472	ENSXMAP00000037867	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.508
ENSXMAP00000026472	LOC102229158	ENSXMAP00000026472	ENSXMAP00000026505	DIX domain-containing protein.	Uncharacterized protein.	0.480
ENSXMAP00000026472	LOC102229429	ENSXMAP00000026472	ENSXMAP00000008141	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.433
ENSXMAP00000026472	LOC102229577	ENSXMAP00000026472	ENSXMAP00000004356	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.415
ENSXMAP00000026472	LOC102232337	ENSXMAP00000026472	ENSXMAP00000028307	DIX domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.475