(21 nodes) Definitive hemopoiesis network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102218172	Small ubiquitin-related modifier. (96 aa)
	LOC102224681	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	gar1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (236 aa)
	sae1	SUMO1 activating enzyme subunit 1. (345 aa)
	kri1	KRI1 homolog. (750 aa)
	SP3	Sp3a transcription factor. (699 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (1036 aa)
	LOC102236231	Sp3b transcription factor. (644 aa)
	adar	Adenosine deaminase RNA specific. (1359 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	LOC102218184	Ubiquitin-like domain-containing protein. (147 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (556 aa)
	LOC102236891	T-cell acute lymphocytic leukemia 1. (392 aa)
	LOC102237594	BHLH domain-containing protein. (458 aa)
	LOC111608133	Microfibril associated protein 5. (163 aa)
	rps24	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (201 aa)
	cbfb	Core-binding factor subunit beta. (188 aa)
	sumo1	Small ubiquitin like modifier 1. (150 aa)
	ENSXMAP00000039212	BHLH domain-containing protein. (116 aa)
	LOC102234345	Small ubiquitin-related modifier. (94 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000039212	cbfb	ENSXMAP00000039212	ENSXMAP00000036077	BHLH domain-containing protein.	Core-binding factor subunit beta.	0.673
LOC102218172	LOC102224681	ENSXMAP00000006717	ENSXMAP00000001129	Small ubiquitin-related modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.983
LOC102218172	LOC102234345	ENSXMAP00000006717	ENSXMAP00000041354	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.901
LOC102218172	sae1	ENSXMAP00000006717	ENSXMAP00000003975	Small ubiquitin-related modifier.	SUMO1 activating enzyme subunit 1.	0.920
LOC102218172	sumo1	ENSXMAP00000006717	ENSXMAP00000037164	Small ubiquitin-related modifier.	Small ubiquitin like modifier 1.	0.667
LOC102218172	sumo2	ENSXMAP00000006717	ENSXMAP00000014573	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.900
LOC102218172	ube2i	ENSXMAP00000006717	ENSXMAP00000018877	Small ubiquitin-related modifier.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.983
LOC102218184	LOC102224681	ENSXMAP00000015392	ENSXMAP00000001129	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.837
LOC102218184	sae1	ENSXMAP00000015392	ENSXMAP00000003975	Ubiquitin-like domain-containing protein.	SUMO1 activating enzyme subunit 1.	0.902
LOC102218184	sumo1	ENSXMAP00000015392	ENSXMAP00000037164	Ubiquitin-like domain-containing protein.	Small ubiquitin like modifier 1.	0.654
LOC102218184	ube2i	ENSXMAP00000015392	ENSXMAP00000018877	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.837
LOC102224681	LOC102218172	ENSXMAP00000001129	ENSXMAP00000006717	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.983
LOC102224681	LOC102218184	ENSXMAP00000001129	ENSXMAP00000015392	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like domain-containing protein.	0.837
LOC102224681	LOC102234345	ENSXMAP00000001129	ENSXMAP00000041354	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.983
LOC102224681	sae1	ENSXMAP00000001129	ENSXMAP00000003975	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	SUMO1 activating enzyme subunit 1.	0.960
LOC102224681	sumo1	ENSXMAP00000001129	ENSXMAP00000037164	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin like modifier 1.	0.976
LOC102224681	sumo2	ENSXMAP00000001129	ENSXMAP00000014573	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.983
LOC102224681	ube2i	ENSXMAP00000001129	ENSXMAP00000018877	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.900
LOC102234345	LOC102218172	ENSXMAP00000041354	ENSXMAP00000006717	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.901
LOC102234345	LOC102224681	ENSXMAP00000041354	ENSXMAP00000001129	Small ubiquitin-related modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.983