STRINGSTRING
smo smo nox4 nox4 ildr2 ildr2 nxnl1 nxnl1 gdf5 gdf5 immt immt mks1 mks1 cep290 cep290 sash3 sash3 LOC102222259 LOC102222259 LOC102224007 LOC102224007 nxnl2 nxnl2 clrn1 clrn1 mtf1 mtf1 pbld pbld rp2 rp2 M4ANT8_XIPMA M4ANT8_XIPMA LOC102224869 LOC102224869 tert tert LOC102229328 LOC102229328 LOC102233539 LOC102233539 nkiras1 nkiras1 sod1 sod1 ush2a ush2a LOC102217479 LOC102217479 LOC102230603 LOC102230603 dctn2 dctn2 KLHL10 KLHL10 LOC102228816 LOC102228816 prlh prlh ca7 ca7 stk11 stk11 Bbs12 Bbs12 M4B019_XIPMA M4B019_XIPMA M4B0G7_XIPMA M4B0G7_XIPMA ZNF830 ZNF830 lamp2 lamp2 bsg bsg SRF SRF rp1l1 rp1l1 LOC102231629 LOC102231629 csrp3 csrp3 prrc1 prrc1 LOC106700083 LOC106700083 LOC102237423 LOC102237423 LOC102217221 LOC102217221 LOC102224296 LOC102224296 LOC102232821 LOC102232821 SRC SRC LOC102235818 LOC102235818 cav1 cav1 bbs10 bbs10 LOC102216933 LOC102216933 LOC102221304 LOC102221304 ankrd11 ankrd11 fxn fxn ENSXMAP00000028313 ENSXMAP00000028313 LOC102235052 LOC102235052 shh shh bag3 bag3 LOC102221305 LOC102221305 LOC102231851 LOC102231851 p2rx1 p2rx1 rb1 rb1 LOC102224329 LOC102224329 ENSXMAP00000031595 ENSXMAP00000031595 ENSXMAP00000031631 ENSXMAP00000031631 ENSXMAP00000031874 ENSXMAP00000031874 cln8 cln8 strap strap ENSXMAP00000032037 ENSXMAP00000032037 crocc crocc Cldn5 Cldn5 ENSXMAP00000032446 ENSXMAP00000032446 LOC102230536 LOC102230536 LOC111610820 LOC111610820 tp53inp2 tp53inp2 fgf2 fgf2 LOC111610425 LOC111610425 LOC102233680 LOC102233680 bcl2 bcl2 CYTL1 CYTL1 LOC102229912 LOC102229912 cd34 cd34 ENSXMAP00000035767 ENSXMAP00000035767 Ezh2 Ezh2 LOC102227197 LOC102227197 fkbp14 fkbp14 LOC111610088 LOC111610088 lrrc45 lrrc45 hdac8 hdac8 pln pln ENSXMAP00000037484 ENSXMAP00000037484 LOC111610433 LOC111610433 ush1c ush1c vps54 vps54 ENSXMAP00000038106 ENSXMAP00000038106 cav3 cav3 LOC102237370 LOC102237370 tjp2 tjp2 LOC102223432 LOC102223432 LOC102227657 LOC102227657 gdf6 gdf6 LOC102234134 LOC102234134 vstm4 vstm4 LOC111610285 LOC111610285 lsr lsr LOC102233648 LOC102233648 dctn1 dctn1 LOC111606281 LOC111606281 mbp mbp M3ZRF2_XIPMA M3ZRF2_XIPMA nphp4 nphp4 acp5 acp5 ift172 ift172 trim32 trim32 mkks mkks usp45 usp45 crb2 crb2 LOC102232326 LOC102232326 LOC102229182 LOC102229182 ncdn ncdn bbs1 bbs1 ctsh ctsh crb1 crb1 ercc6 ercc6 LOC102217163 LOC102217163 itgb6 itgb6 emc3 emc3 LOC102225266 LOC102225266 ccnd1 ccnd1 lrrk1 lrrk1 LOC102225202 LOC102225202 LOC102216881 LOC102216881 ccdc66 ccdc66 M3ZFC9_XIPMA M3ZFC9_XIPMA cracd cracd whrn whrn LOC102222465 LOC102222465 tnfsf11 tnfsf11 ift57 ift57 disc1 disc1 ccn2 ccn2 ttk ttk LOC102229288 LOC102229288 uhrf1 uhrf1 cluap1 cluap1 nkiras2 nkiras2 LOC102224407 LOC102224407 EZH1 EZH1 BAX BAX Eys Eys LOC102233323 LOC102233323 tmem175 tmem175 prdm14 prdm14 LOC102231937 LOC102231937 bbs4 bbs4 LOC102228863 LOC102228863 nrf1 nrf1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
nox4FAD-binding FR-type domain-containing protein. (559 aa)
ildr2Immunoglobulin-like domain containing receptor 2. (627 aa)
nxnl1Nucleoredoxin like 1. (231 aa)
gdf5Growth differentiation factor 5. (524 aa)
immtMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (766 aa)
mks1MKS transition zone complex subunit 1. (562 aa)
cep290Centrosomal protein 290. (2250 aa)
sash3SAM and SH3 domain containing 3. (398 aa)
LOC102222259V-set and transmembrane domain containing 4a. (351 aa)
LOC102224007Lysophosphatidylcholine acyltransferase 1. (497 aa)
nxnl2Nucleoredoxin like 2. (156 aa)
clrn1Clarin 1. (232 aa)
mtf1Metal-regulatory transcription factor 1. (816 aa)
pbldPhenazine biosynthesis like protein domain containing. (287 aa)
rp2Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. (370 aa)
M4ANT8_XIPMAClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
LOC102224869Uncharacterized protein. (1469 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1097 aa)
LOC102229328RP1 axonemal microtubule associated. (269 aa)
LOC102233539Purinergic receptor P2X, ligand-gated ion channel, 7. (622 aa)
nkiras1NFKB inhibitor interacting Ras-like 1. (192 aa)
sod1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
ush2aUsher syndrome 2A (autosomal recessive, mild). (5058 aa)
LOC102217479Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
LOC102230603Calbindin 2a. (270 aa)
dctn2Dynactin 2 (p50). (400 aa)
KLHL10Kelch like family member 10. (591 aa)
LOC102228816Zgc:171965; Belongs to the G-protein coupled receptor 1 family. (431 aa)
prlhProlactin releasing hormone 2. (122 aa)
ca7Carbonic anhydrase VII; Belongs to the alpha-carbonic anhydrase family. (262 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
Bbs12Bardet-Biedl syndrome 12. (622 aa)
M4B019_XIPMAUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1501 aa)
M4B0G7_XIPMAUncharacterized protein. (408 aa)
ZNF830Zinc finger protein 830. (335 aa)
lamp2Lysosomal-associated membrane protein 2. (416 aa)
bsgBasigin. (388 aa)
SRFSerum response factor. (597 aa)
rp1l1Uncharacterized protein. (2407 aa)
LOC102231629Fibroblast growth factor receptor. (831 aa)
csrp3Cysteine and glycine-rich protein 3 (cardiac LIM protein). (210 aa)
prrc1Proline-rich coiled-coil 1. (438 aa)
LOC106700083Fibronectin type-III domain-containing protein. (614 aa)
LOC102237423Uncharacterized protein. (128 aa)
LOC102217221Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
LOC102224296Tight junction protein 1b; Belongs to the MAGUK family. (1922 aa)
LOC102232821Nucleoredoxin like 1. (232 aa)
SRCTyrosine-protein kinase. (550 aa)
LOC102235818Peptidylprolyl isomerase. (207 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
bbs10Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (635 aa)
LOC102216933Tight junction protein 1a; Belongs to the MAGUK family. (1779 aa)
LOC102221304Lebercilin LCA5. (806 aa)
ankrd11Ankyrin repeat domain 11. (2826 aa)
fxnFrataxin. (213 aa)
ENSXMAP00000028313Uncharacterized protein. (445 aa)
LOC102235052Growth differentiation factor 11. (389 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
bag3BCL2 associated athanogene 3. (513 aa)
LOC102221305GATA binding protein 1a. (438 aa)
LOC102231851Homer scaffold protein 1b. (402 aa)
p2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (432 aa)
rb1Retinoblastoma susceptibility protein. (912 aa)
LOC102224329Innate immunity activator b. (613 aa)
ENSXMAP00000031595Doublecortin domain-containing protein. (4422 aa)
ENSXMAP00000031631Integrin_b_cyt domain-containing protein. (97 aa)
ENSXMAP00000031874Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1535 aa)
cln8CLN8 transmembrane ER and ERGIC protein. (288 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
ENSXMAP00000032037PDZ domain-containing protein. (120 aa)
croccUncharacterized protein. (2009 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (165 aa)
ENSXMAP00000032446Ubiquitin-like domain-containing protein. (138 aa)
LOC102230536BTB domain-containing protein. (579 aa)
LOC111610820C-type lectin domain-containing protein. (254 aa)
tp53inp2Uncharacterized protein. (320 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC111610425C-type lectin domain-containing protein. (245 aa)
LOC102233680Whirlin b. (978 aa)
bcl2BCL2 apoptosis regulator b. (229 aa)
CYTL1Cytokine like 1. (146 aa)
LOC102229912MADS-box domain-containing protein. (469 aa)
cd34Si:ch211-286o17.1. (318 aa)
ENSXMAP00000035767Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (414 aa)
Ezh2Uncharacterized protein. (92 aa)
LOC102227197Tyrosine-protein kinase. (542 aa)
fkbp14Peptidylprolyl isomerase. (211 aa)
LOC111610088C-type lectin domain-containing protein. (242 aa)
lrrc45Leucine rich repeat containing 45. (674 aa)
hdac8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (391 aa)
plnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (53 aa)
ENSXMAP00000037484Uncharacterized protein. (227 aa)
LOC111610433C-type lectin domain-containing protein. (242 aa)
ush1cUsher syndrome 1C. (551 aa)
vps54VPS54 subunit of GARP complex. (994 aa)
ENSXMAP00000038106Parkin RBR E3 ubiquitin protein ligase. (257 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
LOC102237370Colony stimulating factor 1b (macrophage). (271 aa)
tjp2Uncharacterized protein; Belongs to the MAGUK family. (1269 aa)
LOC102223432Uncharacterized protein. (309 aa)
LOC102227657Tight junction protein 3; Belongs to the MAGUK family. (1332 aa)
gdf6Growth differentiation factor 6a. (418 aa)
LOC102234134Occludin a. (506 aa)
vstm4V-set and transmembrane domain containing 4b. (351 aa)
LOC111610285Mannose binding lectin 2. (251 aa)
lsrLipolysis stimulated lipoprotein receptor. (606 aa)
LOC102233648Uncharacterized protein. (309 aa)
dctn1Dynactin 1b. (1249 aa)
LOC111606281Uncharacterized protein. (2379 aa)
mbpMyelin basic protein b. (144 aa)
M3ZRF2_XIPMAUncharacterized protein. (676 aa)
nphp4Uncharacterized protein. (1441 aa)
acp5Tartrate-resistant acid phosphatase type 5. (335 aa)
ift172Intraflagellar transport 172. (1718 aa)
trim32Tripartite motif containing 32. (622 aa)
mkksMcKusick-Kaufman syndrome. (564 aa)
usp45Ubiquitin carboxyl-terminal hydrolase. (810 aa)
crb2Crumbs cell polarity complex component 2b. (1458 aa)
LOC102232326BTB domain-containing protein. (586 aa)
LOC102229182Ciliary rootlet coiled-coil, rootletin family member 2. (1434 aa)
ncdnNeurochondrin. (764 aa)
bbs1Bardet-Biedl syndrome 1. (583 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (325 aa)
crb1Crumbs cell polarity complex component 1. (1338 aa)
ercc6Excision repair cross-complementation group 6. (1470 aa)
LOC102217163IG domain-containing protein. (542 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (665 aa)
emc3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
LOC102225266Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
lrrk1Uncharacterized protein. (2017 aa)
LOC102225202Uncharacterized protein. (270 aa)
LOC102216881Transforming growth factor beta; Belongs to the TGF-beta family. (394 aa)
ccdc66CCDC66 domain-containing protein. (850 aa)
M3ZFC9_XIPMAUncharacterized protein. (629 aa)
cracdSi:dkeyp-117h8.2. (1028 aa)
whrnWhirlin a. (476 aa)
LOC102222465C-type lectin domain-containing protein. (333 aa)
tnfsf11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
ift57Intraflagellar transport 57 homolog (Chlamydomonas). (415 aa)
disc1DISC1 scaffold protein. (704 aa)
ccn2Cellular communication network factor 2a. (346 aa)
ttkTtk protein kinase. (916 aa)
LOC102229288Secretagogin, EF-hand calcium binding protein. (272 aa)
uhrf1Ubiquitin-like with PHD and ring finger domains 1. (780 aa)
cluap1Clusterin associated protein 1. (421 aa)
nkiras2NFKB inhibitor interacting Ras-like 2. (192 aa)
LOC102224407Dynactin 1a. (1265 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (770 aa)
BAXBCL2 associated X, apoptosis regulator. (190 aa)
EysUncharacterized protein. (350 aa)
LOC102233323BTB domain-containing protein. (591 aa)
tmem175Transmembrane protein 175. (520 aa)
prdm14PR domain containing 14. (514 aa)
LOC102231937Innate immunity activator a. (566 aa)
bbs4Bardet-Biedl syndrome 4. (537 aa)
LOC102228863Calbindin 2b. (271 aa)
nrf1Nuclear respiratory factor 1. (500 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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