62 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	inha	Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (346 aa)
	LOC102233502	Growth differentiation factor 3. (377 aa)
	itgb6	Integrin beta; Belongs to the integrin beta chain family. (665 aa)
	LOC102218062	Inhibin subunit beta B. (393 aa)
	LOC102223630	Mothers against decapentaplegic homolog. (507 aa)
	LOC102223216	Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
	smad6	Mothers against decapentaplegic homolog. (492 aa)
	smad3	Mothers against decapentaplegic homolog. (425 aa)
	LOC102226271	JunE proto-oncogene, AP-1 transcription factor subunit. (324 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
	LOC102224322	Mothers against decapentaplegic homolog. (467 aa)
	LOC102228719	Mothers against decapentaplegic homolog. (503 aa)
	LOC102236757	Bone morphogenetic protein 10, like. (462 aa)
	LOC102227173	Bone morphogenetic protein 6. (428 aa)
	LOC102216611	Uncharacterized protein. (563 aa)
	smad9	Mothers against decapentaplegic homolog. (467 aa)
	LOC102224264	Growth differentiation factor 2. (415 aa)
	bmp3	Bone morphogenetic protein 3. (463 aa)
	LOC102223458	Uncharacterized protein. (348 aa)
	gdf5	Growth differentiation factor 5. (524 aa)
	LOC102218734	TGF_BETA_2 domain-containing protein. (386 aa)
	LOC102231897	TGF_BETA_2 domain-containing protein. (384 aa)
	LOC102235711	Left-right determination factor. (361 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	nodal	Nodal-related 2. (378 aa)
	slc33a1	Solute carrier family 33 member 1. (550 aa)
	LOC102237495	Southpaw. (408 aa)
	LOC102225600	Inhibin subunit beta Aa. (381 aa)
	smad2	Mothers against decapentaplegic homolog. (474 aa)
	LOC102225323	Mothers against decapentaplegic homolog. (563 aa)
	jade2	Jade family PHD finger 2. (877 aa)
	LOC102227900	Mothers against decapentaplegic homolog. (472 aa)
	ENSXMAP00000023172	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (288 aa)
	bmp7	Bone morphogenetic protein 7b. (449 aa)
	LOC102234096	Bone morphogenetic protein 7a. (452 aa)
	bmp5	Bone morphogenetic protein 5. (460 aa)
	ski	V-ski avian sarcoma viral oncogene homolog a. (718 aa)
	bmp10	Bone morphogenetic protein 10. (488 aa)
	LOC102235052	Growth differentiation factor 11. (389 aa)
	cited1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (152 aa)
	bmp15	Bone morphogenetic protein 15. (439 aa)
	SMAD4	Mothers against decapentaplegic homolog. (512 aa)
	ENSXMAP00000031631	Integrin_b_cyt domain-containing protein. (97 aa)
	smad1	Mothers against decapentaplegic homolog. (496 aa)
	ENSXMAP00000032374	TGF_BETA_2 domain-containing protein. (129 aa)
	ENSXMAP00000033320	TGFb_propeptide domain-containing protein. (144 aa)
	LOC102223193	RNA binding motif protein 4.3. (340 aa)
	LOC102237658	Myostatin a. (366 aa)
	INHBC	Inhibin subunit beta C. (383 aa)
	LOC102229905	TGF_BETA_2 domain-containing protein. (532 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1571 aa)
	LOC102223934	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1531 aa)
	smad7	Mothers against decapentaplegic homolog. (378 aa)
	bmp4	Bone morphogenetic protein 4. (399 aa)
	bmp8a	Bone morphogenetic protein 8a. (431 aa)
	ENSXMAP00000039114	Bone morphogenetic protein 16. (511 aa)
	gdf6	Growth differentiation factor 6a. (418 aa)
	LOC102222860	Uncharacterized protein. (346 aa)
	INHBB	Inhibin subunit beta B. (394 aa)
	gdf10	Growth differentiation factor 10b. (443 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	LOC102235035	BTB (POZ) domain containing 11a. (1107 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000023172	LOC102224322	ENSXMAP00000023172	ENSXMAP00000004510	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mothers against decapentaplegic homolog.	0.472
ENSXMAP00000023172	SMAD3	ENSXMAP00000023172	ENSXMAP00000041069	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mothers against decapentaplegic homolog.	0.660
ENSXMAP00000023172	smad2	ENSXMAP00000023172	ENSXMAP00000020548	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mothers against decapentaplegic homolog.	0.472
ENSXMAP00000023172	smad3	ENSXMAP00000023172	ENSXMAP00000003571	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mothers against decapentaplegic homolog.	0.659
ENSXMAP00000031631	LOC102223216	ENSXMAP00000031631	ENSXMAP00000003201	Integrin_b_cyt domain-containing protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.636
ENSXMAP00000031631	TGFB3	ENSXMAP00000031631	ENSXMAP00000003979	Integrin_b_cyt domain-containing protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.548
ENSXMAP00000031631	itgb6	ENSXMAP00000031631	ENSXMAP00000001797	Integrin_b_cyt domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.648
ENSXMAP00000031631	tgfb3	ENSXMAP00000031631	ENSXMAP00000014751	Integrin_b_cyt domain-containing protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.548
ENSXMAP00000032374	INHBB	ENSXMAP00000032374	ENSXMAP00000040138	TGF_BETA_2 domain-containing protein.	Inhibin subunit beta B.	0.901
ENSXMAP00000032374	INHBC	ENSXMAP00000032374	ENSXMAP00000034595	TGF_BETA_2 domain-containing protein.	Inhibin subunit beta C.	0.902
ENSXMAP00000032374	LOC102218062	ENSXMAP00000032374	ENSXMAP00000002123	TGF_BETA_2 domain-containing protein.	Inhibin subunit beta B.	0.901
ENSXMAP00000032374	LOC102231897	ENSXMAP00000032374	ENSXMAP00000014534	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.901
ENSXMAP00000032374	LOC102233502	ENSXMAP00000032374	ENSXMAP00000001284	TGF_BETA_2 domain-containing protein.	Growth differentiation factor 3.	0.751
ENSXMAP00000032374	LOC102235711	ENSXMAP00000032374	ENSXMAP00000014712	TGF_BETA_2 domain-containing protein.	Left-right determination factor.	0.959
ENSXMAP00000032374	LOC102237495	ENSXMAP00000032374	ENSXMAP00000017931	TGF_BETA_2 domain-containing protein.	Southpaw.	0.901
ENSXMAP00000032374	nodal	ENSXMAP00000032374	ENSXMAP00000015144	TGF_BETA_2 domain-containing protein.	Nodal-related 2.	0.901
ENSXMAP00000039114	LOC102223630	ENSXMAP00000039114	ENSXMAP00000002368	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.568
ENSXMAP00000039114	LOC102224322	ENSXMAP00000039114	ENSXMAP00000004510	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.523
ENSXMAP00000039114	LOC102225323	ENSXMAP00000039114	ENSXMAP00000021000	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.675
ENSXMAP00000039114	LOC102227173	ENSXMAP00000039114	ENSXMAP00000006033	Bone morphogenetic protein 16.	Bone morphogenetic protein 6.	0.600