(15 nodes) Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress network (Xiphophorus maculatus)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	LOC102231273	Tribbles pseudokinase 3. (351 aa)
	LOC102227508	CCAAT enhancer binding protein beta. (287 aa)
	tmem117	Transmembrane protein 117. (520 aa)
	LOC102216394	Protein kinase domain-containing protein. (344 aa)
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	ddit3	DNA-damage-inducible transcript 3. (311 aa)
	LOC102222042	Protein kinase domain-containing protein. (1036 aa)
	ern1	Endoplasmic reticulum to nucleus signaling 1. (1060 aa)
	LOC102238210	Zgc:153993. (189 aa)
	LOC102232234	Activating transcription factor 4a. (424 aa)
	BAX	BCL2 associated X, apoptosis regulator. (190 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (255 aa)
	LOC106700271	Uncharacterized protein. (207 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (650 aa)
	bag6	BCL2 associated athanogene 6. (1212 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	LOC102238210	ENSXMAP00000009256	ENSXMAP00000001536	BCL2 associated X, apoptosis regulator.	Zgc:153993.	0.987
BAX	LOC106700271	ENSXMAP00000009256	ENSXMAP00000009257	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.903
BAX	aifm1	ENSXMAP00000009256	ENSXMAP00000012380	BCL2 associated X, apoptosis regulator.	Apoptosis inducing factor mitochondrion associated 1.	0.923
BAX	bcl2	ENSXMAP00000009256	ENSXMAP00000034296	BCL2 associated X, apoptosis regulator.	BCL2 apoptosis regulator b.	0.995
LOC102222042	ern1	ENSXMAP00000035450	ENSXMAP00000001340	Protein kinase domain-containing protein.	Endoplasmic reticulum to nucleus signaling 1.	0.904
LOC102227508	LOC102231273	ENSXMAP00000019712	ENSXMAP00000006191	CCAAT enhancer binding protein beta.	Tribbles pseudokinase 3.	0.552
LOC102227508	LOC102232234	ENSXMAP00000019712	ENSXMAP00000008054	CCAAT enhancer binding protein beta.	Activating transcription factor 4a.	0.962
LOC102227508	ddit3	ENSXMAP00000019712	ENSXMAP00000017955	CCAAT enhancer binding protein beta.	DNA-damage-inducible transcript 3.	0.843
LOC102231273	LOC102227508	ENSXMAP00000006191	ENSXMAP00000019712	Tribbles pseudokinase 3.	CCAAT enhancer binding protein beta.	0.552
LOC102231273	LOC102232234	ENSXMAP00000006191	ENSXMAP00000008054	Tribbles pseudokinase 3.	Activating transcription factor 4a.	0.831
LOC102231273	ddit3	ENSXMAP00000006191	ENSXMAP00000017955	Tribbles pseudokinase 3.	DNA-damage-inducible transcript 3.	0.595
LOC102232234	LOC102227508	ENSXMAP00000008054	ENSXMAP00000019712	Activating transcription factor 4a.	CCAAT enhancer binding protein beta.	0.962
LOC102232234	LOC102231273	ENSXMAP00000008054	ENSXMAP00000006191	Activating transcription factor 4a.	Tribbles pseudokinase 3.	0.831
LOC102232234	ddit3	ENSXMAP00000008054	ENSXMAP00000017955	Activating transcription factor 4a.	DNA-damage-inducible transcript 3.	0.985
LOC102232234	ern1	ENSXMAP00000008054	ENSXMAP00000001340	Activating transcription factor 4a.	Endoplasmic reticulum to nucleus signaling 1.	0.515
LOC102238210	BAX	ENSXMAP00000001536	ENSXMAP00000009256	Zgc:153993.	BCL2 associated X, apoptosis regulator.	0.987
LOC102238210	LOC106700271	ENSXMAP00000001536	ENSXMAP00000009257	Zgc:153993.	Uncharacterized protein.	0.978
LOC102238210	aifm1	ENSXMAP00000001536	ENSXMAP00000012380	Zgc:153993.	Apoptosis inducing factor mitochondrion associated 1.	0.936
LOC102238210	bcl2	ENSXMAP00000001536	ENSXMAP00000034296	Zgc:153993.	BCL2 apoptosis regulator b.	0.983
LOC106700271	BAX	ENSXMAP00000009257	ENSXMAP00000009256	Uncharacterized protein.	BCL2 associated X, apoptosis regulator.	0.903