(48 nodes) Chromosome organization involved in meiotic cell cycle network (Xiphophorus maculatus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	smc4	Structural maintenance of chromosomes protein. (1326 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
	fancd2	FA complementation group D2. (1235 aa)
	SGO1	Shugoshin_C domain-containing protein. (636 aa)
	rad51c	RAD51 paralog C. (352 aa)
	LOC102224556	Uncharacterized protein. (192 aa)
	Terb1	Uncharacterized protein. (337 aa)
	smc2	Structural maintenance of chromosomes protein. (1200 aa)
	ncapd3	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1404 aa)
	bub1b	BUB1 mitotic checkpoint serine/threonine kinase Bb. (430 aa)
	Meioc	Uncharacterized protein. (219 aa)
	majin	Membrane anchored junction protein. (241 aa)
	M4A3H1_XIPMA	HORMA domain containing 1. (241 aa)
	Atrx	ATRX chromatin remodeler. (1195 aa)
	ncaph	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (726 aa)
	C1orf146	Chromosome 1 open reading frame 146. (172 aa)
	ncapd2	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1370 aa)
	meiob	Methionine sulfoxide reductase B1b. (425 aa)
	LOC102233674	Uncharacterized protein. (1901 aa)
	dmc1	DNA meiotic recombinase 1; Belongs to the RecA family. (274 aa)
	ndc1	NDC1 transmembrane nucleoporin. (669 aa)
	sirt7	Sirtuin 7. (408 aa)
	msh5	MutS homolog 5. (787 aa)
	LOC102221997	Testis expressed 11. (807 aa)
	bag6	BCL2 associated athanogene 6. (1212 aa)
	trip13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (420 aa)
	atm	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2875 aa)
	spo11	SPO11 initiator of meiotic double stranded breaks. (387 aa)
	terb2	Telomere repeat binding bouquet formation protein 2. (211 aa)
	ccne2	Cyclin E2; Belongs to the cyclin family. (394 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (754 aa)
	ENSXMAP00000028253	Si:dkey-40g16.5. (135 aa)
	ENSXMAP00000028709	Uncharacterized protein. (78 aa)
	LOC111611385	Uncharacterized protein. (612 aa)
	psmc3ip	PSMC3 interacting protein. (220 aa)
	rec8	Uncharacterized protein. (541 aa)
	syce3	Uncharacterized protein. (98 aa)
	msh4	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (912 aa)
	ENSXMAP00000031754	Uncharacterized protein. (244 aa)
	LOC111610367	ANK_REP_REGION domain-containing protein. (488 aa)
	mlh3	MutL homolog 3 (E. coli). (1151 aa)
	ccnb1ip1	Cyclin B1 interacting protein 1. (264 aa)
	ENSXMAP00000035484	Zebrafish testis-expressed 38. (263 aa)
	Ncaph2	CNDH2_N domain-containing protein. (56 aa)
	ENSXMAP00000036829	Uncharacterized protein. (329 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1312 aa)
	Bub1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (210 aa)
	ENSXMAP00000041423	PR domain containing 9. (740 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atrx	atm	ENSXMAP00000009158	ENSXMAP00000016978	ATRX chromatin remodeler.	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.507
Atrx	bub1b	ENSXMAP00000009158	ENSXMAP00000006577	ATRX chromatin remodeler.	BUB1 mitotic checkpoint serine/threonine kinase Bb.	0.479
Atrx	rad51	ENSXMAP00000009158	ENSXMAP00000000592	ATRX chromatin remodeler.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.815
Atrx	rad51c	ENSXMAP00000009158	ENSXMAP00000003353	ATRX chromatin remodeler.	RAD51 paralog C.	0.447
Bub1	LOC111611385	ENSXMAP00000040519	ENSXMAP00000029398	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.949
Bub1	SGO1	ENSXMAP00000040519	ENSXMAP00000003254	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Shugoshin_C domain-containing protein.	0.921
Bub1	bub1b	ENSXMAP00000040519	ENSXMAP00000006577	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	BUB1 mitotic checkpoint serine/threonine kinase Bb.	0.949
Bub1	dmc1	ENSXMAP00000040519	ENSXMAP00000012603	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA meiotic recombinase 1; Belongs to the RecA family.	0.539
Bub1	ncapd2	ENSXMAP00000040519	ENSXMAP00000011504	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.509
Bub1	ncapd3	ENSXMAP00000040519	ENSXMAP00000005730	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.	0.403
Bub1	ncaph	ENSXMAP00000040519	ENSXMAP00000010225	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	0.766
Bub1	rad51	ENSXMAP00000040519	ENSXMAP00000000592	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.679
Bub1	rad51c	ENSXMAP00000040519	ENSXMAP00000003353	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	RAD51 paralog C.	0.539
Bub1	smc2	ENSXMAP00000040519	ENSXMAP00000004592	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Structural maintenance of chromosomes protein.	0.541
Bub1	smc4	ENSXMAP00000040519	ENSXMAP00000018365	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Structural maintenance of chromosomes protein.	0.584
Bub1	trip13	ENSXMAP00000040519	ENSXMAP00000014092	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.	0.566
C1orf146	LOC102221997	ENSXMAP00000010783	ENSXMAP00000013251	Chromosome 1 open reading frame 146.	Testis expressed 11.	0.416
C1orf146	msh4	ENSXMAP00000010783	ENSXMAP00000031743	Chromosome 1 open reading frame 146.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.539
C1orf146	msh5	ENSXMAP00000010783	ENSXMAP00000013099	Chromosome 1 open reading frame 146.	MutS homolog 5.	0.465
ENSXMAP00000028709	LOC111611385	ENSXMAP00000028709	ENSXMAP00000029398	Uncharacterized protein.	Uncharacterized protein.	0.949