31 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102227944	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
	traf3ip2	SEFIR domain-containing protein. (414 aa)
	prpf19	Pre-mRNA processing factor 19. (505 aa)
	hectd1	HECT domain containing 1. (2526 aa)
	BFAR	Bifunctional apoptosis regulator. (559 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
	LOC102219466	Si:ch211-81a5.1. (288 aa)
	rnf4	Ring finger protein 4. (191 aa)
	LOC102217271	TRAF3 interacting protein 2-like. (439 aa)
	rnf8	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (473 aa)
	traf3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (590 aa)
	Ube2v2	Ubiquitin-conjugating enzyme E2 variant 2. (181 aa)
	LOC102223019	Ring finger protein 126. (312 aa)
	arih2	RBR-type E3 ubiquitin transferase. (511 aa)
	rnf152	Ring finger protein 152. (172 aa)
	LOC102217350	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (597 aa)
	LOC102222761	E3 ubiquitin-protein ligase. (869 aa)
	rnf115	Ring finger protein 115. (314 aa)
	ube2g1	Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
	ube2n	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)
	LOC102231293	RING-type domain-containing protein. (325 aa)
	LOC102222460	Si:ch211-113e8.10. (763 aa)
	ENSXMAP00000032446	Ubiquitin-like domain-containing protein. (138 aa)
	LOC102233408	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
	UBE2O	Ubiquitin conjugating enzyme E2 O. (1396 aa)
	LOC102222270	UBIQUITIN_CONJUGAT_2 domain-containing protein. (197 aa)
	ENSXMAP00000038106	Parkin RBR E3 ubiquitin protein ligase. (257 aa)
	LOC102221826	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
	ube2v1	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	LOC102225258	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	LOC102233519	E3 ubiquitin-protein ligase. (880 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BFAR	LOC102222270	ENSXMAP00000011607	ENSXMAP00000035159	Bifunctional apoptosis regulator.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.443
BFAR	Ube2v2	ENSXMAP00000011607	ENSXMAP00000019078	Bifunctional apoptosis regulator.	Ubiquitin-conjugating enzyme E2 variant 2.	0.443
BFAR	rnf8	ENSXMAP00000011607	ENSXMAP00000017393	Bifunctional apoptosis regulator.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.522
BFAR	ube2v1	ENSXMAP00000011607	ENSXMAP00000041535	Bifunctional apoptosis regulator.	Ubiquitin-conjugating enzyme E2 variant 1.	0.469
ENSXMAP00000032446	LOC102221826	ENSXMAP00000032446	ENSXMAP00000039742	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.584
ENSXMAP00000032446	LOC102222270	ENSXMAP00000032446	ENSXMAP00000035159	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.591
ENSXMAP00000032446	LOC102225258	ENSXMAP00000032446	ENSXMAP00000004065	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.820
ENSXMAP00000032446	Ube2v2	ENSXMAP00000032446	ENSXMAP00000019078	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2 variant 2.	0.595
ENSXMAP00000032446	ube2g1	ENSXMAP00000032446	ENSXMAP00000025933	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.584
ENSXMAP00000032446	ube2n	ENSXMAP00000032446	ENSXMAP00000026888	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.	0.820
ENSXMAP00000032446	ube2v1	ENSXMAP00000032446	ENSXMAP00000041535	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2 variant 1.	0.966
ENSXMAP00000038106	LOC102221826	ENSXMAP00000038106	ENSXMAP00000039742	Parkin RBR E3 ubiquitin protein ligase.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.584
ENSXMAP00000038106	LOC102222270	ENSXMAP00000038106	ENSXMAP00000035159	Parkin RBR E3 ubiquitin protein ligase.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.591
ENSXMAP00000038106	LOC102225258	ENSXMAP00000038106	ENSXMAP00000004065	Parkin RBR E3 ubiquitin protein ligase.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.820
ENSXMAP00000038106	Ube2v2	ENSXMAP00000038106	ENSXMAP00000019078	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2 variant 2.	0.595
ENSXMAP00000038106	ube2g1	ENSXMAP00000038106	ENSXMAP00000025933	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.584
ENSXMAP00000038106	ube2n	ENSXMAP00000038106	ENSXMAP00000026888	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.	0.820
ENSXMAP00000038106	ube2v1	ENSXMAP00000038106	ENSXMAP00000041535	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2 variant 1.	0.966
LOC102217271	LOC102217350	ENSXMAP00000015925	ENSXMAP00000024198	TRAF3 interacting protein 2-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.420
LOC102217271	LOC102227944	ENSXMAP00000015925	ENSXMAP00000004922	TRAF3 interacting protein 2-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.420