(26 nodes) Protein K11-linked ubiquitination network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSXMAP00000032446	Ubiquitin-like domain-containing protein. (138 aa)
	anapc5	Anaphase promoting complex subunit 5. (773 aa)
	ENSXMAP00000038106	Parkin RBR E3 ubiquitin protein ligase. (257 aa)
	anapc13	Anaphase promoting complex subunit 13. (74 aa)
	ube2l3	Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	anapc4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (802 aa)
	anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (809 aa)
	ube2c	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
	ube2h	Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	Rnf26	Ring finger protein 26. (451 aa)
	ube2b	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	UBE2H	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	ube2s	Ubiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (236 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
	anapc1	Anaphase promoting complex subunit 1. (1822 aa)
	rnf4	Ring finger protein 4. (191 aa)
	AREL1	Apoptosis resistant E3 ubiquitin protein ligase 1. (1019 aa)
	ube2a	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
	cdc27	Cell division cycle 27. (803 aa)
	LOC102233900	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	cdc26	Cell division cycle 26 homolog. (94 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	LOC102223678	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	anapc10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000032446	LOC102223678	ENSXMAP00000032446	ENSXMAP00000001949	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.766
ENSXMAP00000032446	LOC102233900	ENSXMAP00000032446	ENSXMAP00000012151	Ubiquitin-like domain-containing protein.	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	0.435
ENSXMAP00000032446	ube2a	ENSXMAP00000032446	ENSXMAP00000013745	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.435
ENSXMAP00000032446	ube2b	ENSXMAP00000032446	ENSXMAP00000025360	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.435
ENSXMAP00000032446	ube2l3	ENSXMAP00000032446	ENSXMAP00000033046	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family.	0.766
ENSXMAP00000032446	ube2s	ENSXMAP00000032446	ENSXMAP00000024303	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family.	0.559
ENSXMAP00000038106	LOC102223678	ENSXMAP00000038106	ENSXMAP00000001949	Parkin RBR E3 ubiquitin protein ligase.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.766
ENSXMAP00000038106	LOC102233900	ENSXMAP00000038106	ENSXMAP00000012151	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	0.435
ENSXMAP00000038106	ube2a	ENSXMAP00000038106	ENSXMAP00000013745	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.435
ENSXMAP00000038106	ube2b	ENSXMAP00000038106	ENSXMAP00000025360	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.435
ENSXMAP00000038106	ube2l3	ENSXMAP00000038106	ENSXMAP00000033046	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family.	0.766
ENSXMAP00000038106	ube2s	ENSXMAP00000038106	ENSXMAP00000024303	Parkin RBR E3 ubiquitin protein ligase.	Ubiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family.	0.559
LOC102223678	ENSXMAP00000032446	ENSXMAP00000001949	ENSXMAP00000032446	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like domain-containing protein.	0.766
LOC102223678	ENSXMAP00000038106	ENSXMAP00000001949	ENSXMAP00000038106	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Parkin RBR E3 ubiquitin protein ligase.	0.766
LOC102223678	LOC102233900	ENSXMAP00000001949	ENSXMAP00000012151	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	0.471
LOC102223678	UBE2H	ENSXMAP00000001949	ENSXMAP00000024945	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.564
LOC102223678	anapc1	ENSXMAP00000001949	ENSXMAP00000017230	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Anaphase promoting complex subunit 1.	0.553
LOC102223678	anapc10	ENSXMAP00000001949	ENSXMAP00000001774	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	0.501
LOC102223678	anapc11	ENSXMAP00000001949	ENSXMAP00000018050	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	APC11 anaphase promoting complex subunit 11 homolog (yeast).	0.510
LOC102223678	anapc2	ENSXMAP00000001949	ENSXMAP00000031445	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Anaphase promoting complex subunit 2; Belongs to the cullin family.	0.521