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| | ascc3 | Activating signal cointegrator 1 complex subunit 3. (2200 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (886 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | M3ZFE3_XIPMA | Excision repair cross-complementation group 6-like. (1042 aa) |
| | LOC102227958 | Chromodomain helicase DNA binding protein 4a. (1585 aa) |
| | dhx36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1065 aa) |
| | MCMDC2 | Minichromosome maintenance domain containing 2. (649 aa) |
| | gtf2f2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (252 aa) |
| | ruvbl1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | chd2 | Chromodomain helicase DNA binding protein 2. (1812 aa) |
| | gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa) |
| | LOC102218810 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (260 aa) |
| | ercc3 | Excision repair cross-complementation group 3. (783 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1023 aa) |
| | ighmbp2 | Immunoglobulin mu DNA binding protein 2. (980 aa) |
| | LOC102237263 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (629 aa) |
| | ddx11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (897 aa) |
| | M3ZPQ6_XIPMA | Helicase for meiosis 1. (869 aa) |
| | top3b | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (858 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (695 aa) |
| | ddx1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1. (740 aa) |
| | rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1165 aa) |
| | LOC102223095 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (503 aa) |
| | brip1 | BRCA1 interacting protein C-terminal helicase 1. (1188 aa) |
| | ruvbl2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (459 aa) |
| | chtf8 | CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (133 aa) |
| | nbn | Nibrin. (831 aa) |
| | chtf18 | AAA domain-containing protein. (922 aa) |
| | fancm | Uncharacterized protein. (1911 aa) |
| | zranb3 | Zinc finger, RAN-binding domain containing 3. (1095 aa) |
| | Atrx | ATRX chromatin remodeler. (1195 aa) |
| | M4A5A7_XIPMA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (586 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (700 aa) |
| | dhx9 | DEAH (Asp-Glu-Ala-His) box helicase 9. (1246 aa) |
| | LOC102236567 | Uncharacterized protein. (1780 aa) |
| | top2a | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1536 aa) |
| | LOC102233674 | Uncharacterized protein. (1901 aa) |
| | recql5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (992 aa) |
| | helq | Helicase, POLQ like. (992 aa) |
| | LOC102228555 | DEAH (Asp-Glu-Ala-His) box polypeptide 32b. (682 aa) |
| | supv3l1 | SUV3-like helicase. (773 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa) |
| | recql4 | RecQ helicase-like 4. (1385 aa) |
| | LOC102230723 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (687 aa) |
| | smarcad1 | Uncharacterized protein. (1090 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (722 aa) |
| | gins3 | GINS complex subunit 3. (211 aa) |
| | aire | PHD-type domain-containing protein. (353 aa) |
| | chd3 | Chromodomain helicase DNA binding protein 3. (1540 aa) |
| | chd9 | Chromodomain helicase DNA binding protein 9. (3004 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (724 aa) |
| | wrnip1 | WRN helicase interacting protein 1. (595 aa) |
| | LOC102229556 | DEAH (Asp-Glu-Ala-His) box polypeptide 32a. (733 aa) |
| | top2b | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1589 aa) |
| | twnk | Twinkle mtDNA helicase. (721 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (816 aa) |
| | chd7 | Chromodomain helicase DNA binding protein 7. (3279 aa) |
| | fbh1 | F-box DNA helicase 1. (1056 aa) |
| | LOC111609624 | ATP-dependent DNA helicase; Belongs to the helicase family. (2786 aa) |
| | gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa) |
| | ENSXMAP00000024871 | MCM domain-containing protein; Belongs to the MCM family. (351 aa) |
| | chd1 | Chromodomain helicase DNA binding protein 1. (1672 aa) |
| | ENSXMAP00000025202 | Uncharacterized protein. (105 aa) |
| | ENSXMAP00000025754 | ATP-dependent DNA helicase; Belongs to the helicase family. (2816 aa) |
| | ENSXMAP00000026410 | ATP-dependent DNA helicase; Belongs to the helicase family. (2248 aa) |
| | blm | BLM RecQ like helicase. (1398 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (357 aa) |
| | recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (642 aa) |
| | ENSXMAP00000032345 | ATP-dependent DNA helicase; Belongs to the helicase family. (2302 aa) |
| | ENSXMAP00000032469 | Chromo domain-containing protein. (485 aa) |
| | xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa) |
| | ENSXMAP00000033369 | Uncharacterized protein. (486 aa) |
| | ercc2 | Excision repair cross-complementation group 2. (760 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (846 aa) |
| | dna2 | Uncharacterized protein. (1324 aa) |
| | Mcm9 | Uncharacterized protein. (158 aa) |
| | chd5 | Uncharacterized protein. (2001 aa) |
| | ENSXMAP00000035797 | annotation not available (2248 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa) |
| | dqx1 | DEAQ box RNA-dependent ATPase 1. (850 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (836 aa) |
| | pot1 | Telo_bind domain-containing protein. (889 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (868 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | chd1l | Chromodomain helicase DNA binding protein 1-like. (1013 aa) |
