(17 nodes) Cholesterol transfer activity network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSXMAP00000030405	Uncharacterized protein. (401 aa)
	mttp	Microsomal triglyceride transfer protein. (888 aa)
	stard5	StAR-related lipid transfer (START) domain containing 5. (193 aa)
	gramd1c	GRAM domain containing 1c. (657 aa)
	LOC102226285	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (541 aa)
	pltp	Phospholipid transfer protein. (554 aa)
	star	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (286 aa)
	abcg8	ATP-binding cassette, sub-family G (WHITE), member 8. (666 aa)
	abcg5	ATP-binding cassette, sub-family G (WHITE), member 5. (657 aa)
	gramd1b	GRAM domain containing 1Bb. (918 aa)
	cetp	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (505 aa)
	ENSXMAP00000026053	Vitellogenin domain-containing protein. (816 aa)
	gramd1a	GRAM domain containing 1A. (905 aa)
	podn	Podocan. (587 aa)
	apob	Apolipoprotein Ba. (4378 aa)
	LOC102234016	Apolipoprotein Bb, tandem duplicate 2. (3542 aa)
	stard3	StAR-related lipid transfer (START) domain containing 3. (455 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000026053	ENSXMAP00000030405	ENSXMAP00000026053	ENSXMAP00000030405	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.400
ENSXMAP00000026053	cetp	ENSXMAP00000026053	ENSXMAP00000022609	Vitellogenin domain-containing protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.665
ENSXMAP00000026053	mttp	ENSXMAP00000026053	ENSXMAP00000005807	Vitellogenin domain-containing protein.	Microsomal triglyceride transfer protein.	0.883
ENSXMAP00000026053	pltp	ENSXMAP00000026053	ENSXMAP00000012289	Vitellogenin domain-containing protein.	Phospholipid transfer protein.	0.475
ENSXMAP00000030405	ENSXMAP00000026053	ENSXMAP00000030405	ENSXMAP00000026053	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.400
ENSXMAP00000030405	cetp	ENSXMAP00000030405	ENSXMAP00000022609	Uncharacterized protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.665
ENSXMAP00000030405	mttp	ENSXMAP00000030405	ENSXMAP00000005807	Uncharacterized protein.	Microsomal triglyceride transfer protein.	0.883
ENSXMAP00000030405	pltp	ENSXMAP00000030405	ENSXMAP00000012289	Uncharacterized protein.	Phospholipid transfer protein.	0.475
LOC102234016	cetp	ENSXMAP00000039703	ENSXMAP00000022609	Apolipoprotein Bb, tandem duplicate 2.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.665
LOC102234016	mttp	ENSXMAP00000039703	ENSXMAP00000005807	Apolipoprotein Bb, tandem duplicate 2.	Microsomal triglyceride transfer protein.	0.883
LOC102234016	pltp	ENSXMAP00000039703	ENSXMAP00000012289	Apolipoprotein Bb, tandem duplicate 2.	Phospholipid transfer protein.	0.475
abcg5	abcg8	ENSXMAP00000018188	ENSXMAP00000018173	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.998
abcg5	mttp	ENSXMAP00000018188	ENSXMAP00000005807	ATP-binding cassette, sub-family G (WHITE), member 5.	Microsomal triglyceride transfer protein.	0.450
abcg8	abcg5	ENSXMAP00000018173	ENSXMAP00000018188	ATP-binding cassette, sub-family G (WHITE), member 8.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.998
abcg8	pltp	ENSXMAP00000018173	ENSXMAP00000012289	ATP-binding cassette, sub-family G (WHITE), member 8.	Phospholipid transfer protein.	0.410
apob	cetp	ENSXMAP00000038969	ENSXMAP00000022609	Apolipoprotein Ba.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.665
apob	mttp	ENSXMAP00000038969	ENSXMAP00000005807	Apolipoprotein Ba.	Microsomal triglyceride transfer protein.	0.883
apob	pltp	ENSXMAP00000038969	ENSXMAP00000012289	Apolipoprotein Ba.	Phospholipid transfer protein.	0.475
cetp	ENSXMAP00000026053	ENSXMAP00000022609	ENSXMAP00000026053	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	Vitellogenin domain-containing protein.	0.665
cetp	ENSXMAP00000030405	ENSXMAP00000022609	ENSXMAP00000030405	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	Uncharacterized protein.	0.665