22 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	skil	SKI-like proto-oncogene a. (771 aa)
	LOC102226269	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (482 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC111612340	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (442 aa)
	LOC102220963	Uncharacterized protein. (646 aa)
	sirt1	Sirtuin 1. (694 aa)
	BAX	BCL2 associated X, apoptosis regulator. (190 aa)
	LOC106700271	Uncharacterized protein. (207 aa)
	LOC102236848	Uncharacterized protein. (472 aa)
	M4A916_XIPMA	Nuclear protein 1b. (85 aa)
	flcn	Folliculin. (551 aa)
	ddit3	DNA-damage-inducible transcript 3. (311 aa)
	fbh1	F-box DNA helicase 1. (1056 aa)
	LOC102219157	NK3 homeobox 1. (196 aa)
	gsdme	Gasdermin Eb. (461 aa)
	bad	BCL2 associated agonist of cell death b. (166 aa)
	msx1	Muscle segment homeobox 1a. (281 aa)
	nck1	Cytoplasmic protein. (394 aa)
	ENSXMAP00000035630	Muscle segment homeobox 3. (147 aa)
	nck2	Cytoplasmic protein. (396 aa)
	styxl1	Serine/threonine/tyrosine interacting-like 1. (333 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	LOC106700271	ENSXMAP00000009256	ENSXMAP00000009257	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.903
BAX	bad	ENSXMAP00000009256	ENSXMAP00000025380	BCL2 associated X, apoptosis regulator.	BCL2 associated agonist of cell death b.	0.751
LOC106700271	BAX	ENSXMAP00000009257	ENSXMAP00000009256	Uncharacterized protein.	BCL2 associated X, apoptosis regulator.	0.903
LOC106700271	bad	ENSXMAP00000009257	ENSXMAP00000025380	Uncharacterized protein.	BCL2 associated agonist of cell death b.	0.806
bad	BAX	ENSXMAP00000025380	ENSXMAP00000009256	BCL2 associated agonist of cell death b.	BCL2 associated X, apoptosis regulator.	0.751
bad	LOC106700271	ENSXMAP00000025380	ENSXMAP00000009257	BCL2 associated agonist of cell death b.	Uncharacterized protein.	0.806
nck1	nck2	ENSXMAP00000027526	ENSXMAP00000038600	Cytoplasmic protein.	Cytoplasmic protein.	0.901
nck2	nck1	ENSXMAP00000038600	ENSXMAP00000027526	Cytoplasmic protein.	Cytoplasmic protein.	0.901