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bckdhb bckdhb bckdha bckdha sucla2 sucla2 dbt dbt mrps36 mrps36 ogdh ogdh Fh Fh idh3g idh3g suclg1 suclg1 OGDH OGDH LOC102220845 LOC102220845 DLST DLST suclg2 suclg2 idh3a idh3a
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (387 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (447 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (478 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (508 aa)
mrps36Mitochondrial ribosomal protein S36. (151 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1022 aa)
FhFumarate hydratase. (494 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (396 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
OGDHOxoglutarate dehydrogenase. (1036 aa)
LOC102220845Dihydrolipoamide S-succinyltransferase. (539 aa)
DLSTDihydrolipoamide S-succinyltransferase. (430 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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