(51 nodes) Sm-like protein family complex network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	ENSXMAP00000030333	SEC63 domain-containing protein. (134 aa)
	lsm2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (93 aa)
	strap	Serine/threonine kinase receptor associated protein. (329 aa)
	lsm4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (188 aa)
	txnl4b	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (175 aa)
	lsm5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	rbmx2	RRM domain-containing protein. (304 aa)
	txnl4a	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	LOC102216861	Survival of motor neuron 1, telomeric. (283 aa)
	ENSXMAP00000037817	Ig-like domain-containing protein. (165 aa)
	prpf8	Pre-mRNA processing factor 8. (2341 aa)
	sf3b2	Splicing factor 3b, subunit 2. (860 aa)
	lsm11	LSM11, U7 small nuclear RNA associated. (304 aa)
	ddx20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (766 aa)
	sf3b1	Splicing factor 3b, subunit 1. (1315 aa)
	rnpc3	RNA-binding region (RNP1, RRM) containing 3. (508 aa)
	kiaa2026	Bromo domain-containing protein. (2238 aa)
	clns1a	Chloride channel, nucleotide-sensitive, 1A. (250 aa)
	snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	prpf4	PRP4 pre-mRNA processing factor 4 homolog (yeast). (463 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (1903 aa)
	snrpa1	Small nuclear ribonucleoprotein polypeptide A. (268 aa)
	gemin8	Gem (nuclear organelle) associated protein 8. (194 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	htatsf1	HIV-1 Tat specific factor 1. (434 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	gemin2	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (258 aa)
	lsm6	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
	trmt13	tRNA methyltransferase 13 homolog. (445 aa)
	gemin6	Gem (nuclear organelle) associated protein 6. (191 aa)
	prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae). (969 aa)
	prpf3	PRP3 pre-mRNA processing factor 3 homolog (yeast). (691 aa)
	inpp5d	Inositol polyphosphate-5-phosphatase D. (1083 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (805 aa)
	usp39	Ubiquitin specific peptidase 39. (499 aa)
	cd2bp2	CD2 (cytoplasmic tail) binding protein 2. (381 aa)
	snrpb2	Small nuclear ribonucleoprotein polypeptide B2. (220 aa)
	gemin4	Gem (nuclear organelle) associated protein 4. (1121 aa)
	c18h19orf54	Zgc:153119. (303 aa)
	snrpa	Small nuclear ribonucleoprotein polypeptide A. (273 aa)
	gemin7	Gem (nuclear organelle) associated protein 7. (128 aa)
	sf3b5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	lsm7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (109 aa)
	ppih	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
	ENSXMAP00000022713	Small nuclear ribonucleoprotein-associated protein. (234 aa)
	gemin5	Gem (nuclear organelle) associated protein 5. (1445 aa)
	lsm8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	prpf18	PRP18 pre-mRNA processing factor 18 homolog (yeast). (385 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000022713	LOC102216861	ENSXMAP00000022713	ENSXMAP00000037183	Small nuclear ribonucleoprotein-associated protein.	Survival of motor neuron 1, telomeric.	0.579
ENSXMAP00000022713	ddx20	ENSXMAP00000022713	ENSXMAP00000007598	Small nuclear ribonucleoprotein-associated protein.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.474
ENSXMAP00000022713	ddx23	ENSXMAP00000022713	ENSXMAP00000017438	Small nuclear ribonucleoprotein-associated protein.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	0.412
ENSXMAP00000022713	gemin2	ENSXMAP00000022713	ENSXMAP00000009560	Small nuclear ribonucleoprotein-associated protein.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.401
ENSXMAP00000022713	gemin4	ENSXMAP00000022713	ENSXMAP00000040514	Small nuclear ribonucleoprotein-associated protein.	Gem (nuclear organelle) associated protein 4.	0.451
ENSXMAP00000022713	gemin5	ENSXMAP00000022713	ENSXMAP00000023967	Small nuclear ribonucleoprotein-associated protein.	Gem (nuclear organelle) associated protein 5.	0.526
ENSXMAP00000022713	gemin7	ENSXMAP00000022713	ENSXMAP00000019603	Small nuclear ribonucleoprotein-associated protein.	Gem (nuclear organelle) associated protein 7.	0.488
ENSXMAP00000022713	gemin8	ENSXMAP00000022713	ENSXMAP00000027460	Small nuclear ribonucleoprotein-associated protein.	Gem (nuclear organelle) associated protein 8.	0.475
ENSXMAP00000022713	lsm11	ENSXMAP00000022713	ENSXMAP00000008254	Small nuclear ribonucleoprotein-associated protein.	LSM11, U7 small nuclear RNA associated.	0.670
ENSXMAP00000022713	lsm7	ENSXMAP00000022713	ENSXMAP00000020542	Small nuclear ribonucleoprotein-associated protein.	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.417
ENSXMAP00000022713	ppih	ENSXMAP00000022713	ENSXMAP00000022660	Small nuclear ribonucleoprotein-associated protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.438
ENSXMAP00000022713	prpf3	ENSXMAP00000022713	ENSXMAP00000016388	Small nuclear ribonucleoprotein-associated protein.	PRP3 pre-mRNA processing factor 3 homolog (yeast).	0.424
ENSXMAP00000022713	prpf4	ENSXMAP00000022713	ENSXMAP00000002749	Small nuclear ribonucleoprotein-associated protein.	PRP4 pre-mRNA processing factor 4 homolog (yeast).	0.409
ENSXMAP00000022713	prpf6	ENSXMAP00000022713	ENSXMAP00000015630	Small nuclear ribonucleoprotein-associated protein.	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).	0.519
ENSXMAP00000022713	prpf8	ENSXMAP00000022713	ENSXMAP00000008559	Small nuclear ribonucleoprotein-associated protein.	Pre-mRNA processing factor 8.	0.479
ENSXMAP00000022713	rnpc3	ENSXMAP00000022713	ENSXMAP00000006534	Small nuclear ribonucleoprotein-associated protein.	RNA-binding region (RNP1, RRM) containing 3.	0.523
ENSXMAP00000022713	sf3b1	ENSXMAP00000022713	ENSXMAP00000007412	Small nuclear ribonucleoprotein-associated protein.	Splicing factor 3b, subunit 1.	0.557
ENSXMAP00000022713	sf3b2	ENSXMAP00000022713	ENSXMAP00000008493	Small nuclear ribonucleoprotein-associated protein.	Splicing factor 3b, subunit 2.	0.494
ENSXMAP00000022713	sf3b5	ENSXMAP00000022713	ENSXMAP00000020018	Small nuclear ribonucleoprotein-associated protein.	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.473
ENSXMAP00000022713	snrpa	ENSXMAP00000022713	ENSXMAP00000018628	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein polypeptide A.	0.740